Trombopag 50 Tablet is used to treat low platelet count due to chronic immune (idiopathic) thrombocytopenic purpura (ITP) or chronic hepatitis C virus (HCV) infection. It is also used to treat severe aplastic anemia.

Trombopag 50 Tablet is a thrombopoietin agonist. It works by stimulating the formation of new platelets in the blood. The function of platelets is to help reduce bleeding.

Take it in the exact dose and duration as advised by the doctor. You may take it on an empty stomach. This medicine is to be swallowed as a whole. Do not chew, crush or break it. Inform your doctor if you have any known allergies to this medication.

The common side effects include nausea, vomiting, diarrhea, upper respiratory tract infection, and urinary tract infection. Let your doctor know if any of these side effects bother you. They may be able able to suggest ways to reduce or treat the symptoms.

Before you take this medicine, inform your doctor if you have any preexisting medical conditions. Let your doctor also know about all the other medicines you are taking. Dose adjustments may be required in patients with liver diseases, inform your doctor.

Uses of Trombopag Tablet

Chronic idiopathic thrombocytopenia
Low platelet count due to ITP or HCV infection
Treatment of Severe Aplastic Anemia

Benefits of Trombopag Tablet

In Low platelet count due to ITP or HCV infection

Trombopag 50 Tablet is used to increase the number of platelets (cells that help the blood clot) to decrease the risk of bleeding in adults and children 1 year of age and older who have chronic idiopathic thrombocytopenic purpura (ITP, an ongoing condition that may cause unusual bruising or bleeding due to an abnormally low number of platelets in the blood). It is used in patients who have not benefited or cannot be treated with other treatments, including medications or surgery to remove the spleen. Trombopag 50 Tablet is also used to increase the number of platelets in people who have hepatitis C (a viral infection that may damage the liver). It is usually given along with other medicines.

In Treatment of Severe Aplastic Anemia

Trombopag 50 Tablet is also used in combination with other medications to treat aplastic anemia, a condition in which the body does not make enough new blood cells, in adults and children 2 years of age and above. Take it as advised by the doctor to get the most benefits.

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Side effects of Trombopag Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Trombopag

Nausea
Diarrhea
Upper respiratory tract infection
Vomiting
Increased liver enzymes
Muscle pain
Urinary tract infection

How to use Trombopag Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Trombopag 50 Tablet is to be taken empty stomach.

How Trombopag Tablet works

Trombopag 50 Tablet is a thrombopoietin agonist. It works by stimulating the formation of new platelets in the blood. Platelets help to reduce or prevent bleeding.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Trombopag 50 Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Trombopag 50 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Trombopag 50 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

UNSAFE

Trombopag 50 Tablet may cause side effects which could affect your ability to drive.
Trombopag 50 Tablet can make you dizzy and have other side effects that make you less alert. This may affect your driving ability.

Kidney

SAFE IF PRESCRIBED

Trombopag 50 Tablet is safe to use in patients with kidney disease. No dose adjustment of Trombopag 50 Tablet is recommended.
However, inform your doctor if you have a kidney disease. Regular monitoring of kidney function tests may is advisable while you are taking this medicine.

Liver

CAUTION

Trombopag 50 Tablet should be used with caution in patients with liver disease. Dose adjustment of Trombopag 50 Tablet may be needed. Please consult your doctor.

What if you forget to take Trombopag Tablet?

If you miss a dose of Trombopag 50 Tablet, skip it and continue with your normal schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Trombopag 50 Tablet

₹484.71/Tablet

Revolade 50mg Tablet

Novartis India Ltd

₹1910.14/tablet

294% costlier

Elborom 50mg Tablet

BDR Pharmaceuticals Internationals Pvt

₹198.9/tablet

59% cheaper

Eltropag 50mg Tablet

Medicamen Biotech Ltd

₹305/tablet

37% cheaper

Cadeltro 50mg Tablet

Cadila Pharmaceuticals Ltd

₹394.29/tablet

19% cheaper

Celbopag 50 Tablet

Celon Laboratories Ltd

₹289.71/tablet

40% cheaper

View all substitutes

Quick tips

Take Trombopag 50 Tablet on an empty stomach, either 1 hour before or 2 hours after meals.
Take Trombopag 50 Tablet at least 2 hours before or 4 hours after eating dairy products and calcium-fortified juices.

Fact Box

Chemical Class

Biphenyls Derivatives

Habit Forming

Therapeutic Class

BLOOD RELATED

Action Class

Thrombopoietin Receptor Agonists (TPO-RAs)

Interaction with drugs

Taking Trombopag with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Atorvastatin (Oral Route) Moderate

Eltrombopag may raise blood levels of Atorvastatin. watch out for symptoms of rhabdomyolysis and myopathy like, abdominal pain, nausea, vomiting, fever, increased heartbeats, conf... More

Tenofovir disoproxil fumarate (Oral Route) Moderate

Eltrombopag may raise blood levels of Tenofovir disoproxil fumarate. watch out for symptoms of Tenofovir disoproxil fumarate side effects such as headache, diarrhea, nausea, fatig... More

Pitavastatin (Oral Route) Moderate

Eltrombopag may raise blood levels of Pitavastatin. watch out for symptoms such as unexplained muscle pain, tenderness or weakness and consult your doctor if you experience them. ... More

Simvastatin (Oral Route) Moderate

Eltrombopag may raise blood levels of Simvastatin. watch out for symptoms of rhabdomyolysis and myopathy like, abdominal pain, nausea, vomiting, fever, increased heartbeats, confu... More

Rosuvastatin (Oral Route) Moderate

Eltrombopag may raise blood levels of Rosuvastatin. watch out for symptoms of rhabdomyolysis and myopathy like, abdominal pain, nausea, vomiting, fever, increased heartbeats, conf... More

View all drug interactions

Patient concerns

Low platelet count ( ITP) since 2013 about 20000 only

Dr. Manju Singh

Homeopathy

Are you taking any medicine for this.

ITP CASE What the best medicine to get out of it Sir I am an ITP case Suffering from low platelet count

Dr. Manju Singh

Homeopathy

Please share your reports.

Patient having Thrombocytopenia and Purpura along vt Altered Sensorium and Loss of eye vision for a day.CT Brain normal.All Blood test including Sr.Sodium,Potasium,BS,Urine Is th Manifestation associated vt Thrombocytopenia and what is th tretment for that? Now Patient is Normal But Thrombocytopenia is still present He had mild oedema over face and upper limbs for a day.But now everything is OK what's the Diagnosis and Treatment ?

Dr. Sunil Sekhri

Diabetology

Patient has low platelet count which could be because of many causes. For diagnosis patient has to be assessed in the clinic and only then a diagnosis can be ascerteiend

My son's platelet count is consistently low. Latest report done two days back shows 1.3 lakh platelet count. I am worried. Does it indicate something serious? What can I do to increase his platelet count.

Dr. Gopal Bansilal Samdani

Paediatrics

Please consult me or any other Paediatrician. will take detail history and will examine your child in detail. At time may ask you relevant investigations if necessary. All information will be used to determine exact underlying cause of problem. Depending upon cause will prescribe you treatment. Your child may need antibiotics. It is mandatory for the customer to have a prescription for the prescription medicines he/she is procuring. Valid prescription cannot be given without diagnosis.

FAQs

Can Trombopag 50 Tablet be crushed?

Trombopag 50 Tablet is a medicine which is used to increase the number of platelets in your blood. This medicine should be taken just as advised by the doctor. You should take this medicine as a whole with a glass of water without crushing or chewing it.

How do you take Trombopag 50 Tablet?

Trombopag 50 Tablet should be taken exactly as prescribed by your doctor. You should take the medicine on an empty stomach either 1 hour before or 2 hours after eating food. Do not alter the dosage or schedule of the medicine unless your prescribing doctor has advised it to do so.

How long does Trombopag 50 Tablet take to work?

Trombopag 50 Tablet prevents the occurrence of bleeding episodes by increasing the number of platelets in the blood. The time taken by this medicine to start working may vary from person to person. Usually, it takes about 2 weeks for the patients to respond to Trombopag 50 Tablet.

Should I avoid any specific foods while taking Trombopag 50 Tablet?

Yes, you may need to avoid certain dairy foods such as cheese, butter, etc. and mineral and vitamin supplements while taking this medicine. Avoid taking these foods four hours before and two hours after taking Trombopag 50 Tablet. If you take these food items or supplements, the medicine may not get absorbed into your body, thereby not acting properly.

How should I store Trombopag 50 Tablet?

This medicine can be stored at room temperature between 20°C to 25°C. Close the bottle tightly and do not remove the desiccant pack if present inside the bottle as it helps to keep the medicine dry.

Can Trombopag 50 Tablet cause serious side effects?

Trombopag 50 Tablet can cause serious side effects like liver problems. The symptoms of liver disease include yellowing of the skin or the whites of the eyes, pain in the upper right area of the stomach, unusual darkening of the urine, and unusual tiredness. The risk of liver problems increases if the patient is infected with hepatitis C virus or is being treated for it. Taking this medicine may also increase the platelet count in the blood, increasing the risk of developing blood clots. This in turn increases your risk of getting a heart attack or stroke and may prove fatal in some cases. Ideally, regular blood tests are done to monitor the liver functions and platelet count while taking Trombopag 50 Tablet. Its use can also worsen cataract, leading to blurring of vision. Consult your doctor immediately if you notice any of the side effects.

What should I do if I miss a dose of Trombopag 50 Tablet?

If you miss a dose of Trombopag 50 Tablet, you should wait and take your next scheduled dose. Do not take more than one dose of this medicine in a single day. Taking a double dose of this medicine in a single day can increase the risk of side effects.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Eltrombopag. East Hanover, New Jersey: Novartis Pharmaceuticals Corporation; 2008 [revised Nov. 2018]. [Accessed 25 Jan. 2019] (online) Available from:
Eltrombopag. Research Triangle Park, NC: GlaxoSmithKline; 2014. [Accessed 07 Apr. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 07 Apr. 2019] (online) Available from:

Marketer details

Name: Natco Pharma Ltd

Address: Natco House, Road No.2, Banjara Hills, Hyderabad-500 034, India

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.