Trypza KP 50mg/325mg Tablet is a pain-relieving medicine. It is used to treat pain and inflammation in conditions like rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis. It may also be used to relieve muscle pain, back pain, toothache, or pain in the ear and throat.

Trypza KP 50mg/325mg Tablet should be taken with food. This will prevent you from getting an upset stomach. The dose and duration will depend on what you are taking it for and how well it helps your symptoms. You should take it as advised by your doctor. Do not take more or use it for a longer duration than recommended by the doctor.

The most common side effects of this medicine include nausea, vomiting, diarrhea, heartburn, stomach pain, and indigestion. If any of these side effects do not resolve with time or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing them.

Before taking it, you should let your doctor know if you have a history of ulcer or bleeding in your stomach, high blood pressure, or have any problems with your heart, kidneys, or liver. Let your doctor also know about all the other medicines you are taking to make sure it is safe for you.

Pregnant or breastfeeding women should consult their doctor before starting treatment. You should also avoid drinking alcohol while you are taking this medicine, as alcohol can cause excessive drowsiness.

Uses of Trypza KP Tablet

Pain relief

Benefits of Trypza KP Tablet

In Pain relief

Trypza KP 50mg/325mg Tablet is a combination of medicines that is used for short term relief of pain, inflammation and swelling. It inhibits release of those chemical messengers in the brain that tell us that we have pain. It effectively relieves back pain, earache, throat pain, toothache, periods pain and pain due to arthritis too.
Take Trypza KP 50mg/325mg Tablet as prescribed by the doctor to get the most benefit. Do not take more or for longer than needed as that can be dangerous. In general, you should take the lowest dose that works, for the shortest possible time. This will help you to go about your daily activities more easily and have a better, more active, quality of life.

Side effects of Trypza KP Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Trypza KP

Nausea
Vomiting
Diarrhea
Heartburn
Stomach pain
Indigestion
Loss of appetite

How to use Trypza KP Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Trypza KP 50mg/325mg Tablet is to be taken with food.

How Trypza KP Tablet works

Trypza KP 50mg/325mg Tablet is a combination of three medicines: Diclofenac, Paracetamol and Trypsin Chymotrypsin which relieve pain. Diclofenac is a non-steroidal antiinflammatory drug (NSAID) and Paracetamol is an antipyretic (fever reducer). They work by blocking the release of certain chemical messengers in the brain that cause pain and fever. Trypsin Chymotrypsin is a combination of enzymes which break down proteins into smaller fragments, thereby making them available for absorption into the blood. They increase blood supply in the affected area and reduce swelling.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Trypza KP 50mg/325mg Tablet.

Pregnancy

CONSULT YOUR DOCTOR

Trypza KP 50mg/325mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Trypza KP 50mg/325mg Tablet during breastfeeding is not available. Please consult your doctor.

Driving

UNSAFE

Trypza KP 50mg/325mg Tablet may cause side effects which could affect your ability to drive.

Kidney

CAUTION

Trypza KP 50mg/325mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Trypza KP 50mg/325mg Tablet may be needed. Please consult your doctor.

Liver

CAUTION

Trypza KP 50mg/325mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Trypza KP 50mg/325mg Tablet may be needed. Please consult your doctor.
However, the use of Trypza KP 50mg/325mg Tablet is not recommended in patients with severe liver disease and active liver disease.

What if you forget to take Trypza KP Tablet?

If you miss a dose of Trypza KP 50mg/325mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Trypza KP 50mg/325mg Tablet

₹15.0/Tablet

Nacrophyl Plus Tablet

Zatropha Pharma

₹8.4/tablet

44% cheaper

Gesicare Plus 50mg/325mg Tablet

Rowlinges Life Science

₹8.5/tablet

43% cheaper

Decoript TC 50mg/325mg Tablet

Kript Pharmaceuticals Private Limited

₹15/tablet

same price

Chymovex Plus 50mg/325mg Tablet

Vexilla Healthcare

₹17.1/tablet

14% costlier

Dipsyn Plus Tablet

Sweadish Lifesciences

₹11/tablet

27% cheaper

View all substitutes

Quick tips

You have been prescribed this combination medicine for relieving pain and inflammation.
Take it with food to avoid getting an upset stomach.
It may cause dizziness and sleepiness. Don't drive or do anything that requires mental focus until you know how it affects you.
Avoid consuming alcohol when taking Trypza KP 50mg/325mg Tablet as it may cause excessive drowsiness and increase the risk of liver damage.
Do not take it with any other medicine containing acetaminophen (drugs for pain/fever or cough-and-cold) without asking your doctor first.

Fact Box

Habit Forming

Therapeutic Class

PAIN ANALGESICS

Patient concerns

One of my teeth is sensitive. It some times pains

Dr. Abhijit Gambhir

Dental Surgery

sensitivity has many causative factors for relief of pain you can take pain killers it will give temporary relief

fever and 2 months pregnant can take combiflan

Dr. Sonu Balhara Ahlawat

Obstetrics and Gynaecology

No take Crocin for pain relief

FAQs

What is Trypza KP 50mg/325mg Tablet?

Trypza KP 50mg/325mg Tablet is a combination of four medicines: Diclofenac, Paracetamol, Trypsin and Chymotrypsin. This medicine helps in decreasing pain and swelling. It lowers the levels of chemical substances in the body that cause pain and swelling.

Can I get addicted to Trypza KP 50mg/325mg Tablet?

No, there are no reports of any patient getting addicted to Trypza KP 50mg/325mg Tablet.

Can I stop taking Trypza KP 50mg/325mg Tablet when my pain is relieved?

Trypza KP 50mg/325mg Tablet is usually used for short term and can be discontinued when your pain is relieved. However, Trypza KP 50mg/325mg Tablet should be continued if your doctor has advised you to do so.

Can the use of Trypza KP 50mg/325mg Tablet cause dizziness?

Yes, the use of Trypza KP 50mg/325mg Tablet can cause dizziness (feeling faint, weak, unsteady or lightheaded) in some patients. If you feel dizzy or lightheaded, it is better to rest for some time and resume once you feel better.

Can the use of Trypza KP 50mg/325mg Tablet cause damage to kidneys?

Yes, long-term use of Trypza KP 50mg/325mg Tablet can cause damage to the kidneys. Normal kidneys produce a chemical called prostaglandins that protects them from damage. Use of painkillers lowers the levels of prostaglandins in the body leading to kidney damage on long-term use. Use of painkillers is not recommended to patients with underlying kidney disease.

Can the use of Trypza KP 50mg/325mg Tablet cause damage to liver?

Trypza KP 50mg/325mg Tablet contains Paracetamol. This medicine is known to cause harm to the liver especially in the doses above the recommended level. Also, avoid drinking alcohol while taking this medicine, as it may further increase your risk of liver damage. Use of this medicine should preferably be avoided in patients with the underlying liver disease. Contact your doctor immediately if you notice any early signs and symptoms of liver damage. These symptoms may include fever, rash, loss of appetite, nausea, vomiting, fatigue, stomach pain, dark urine, yellow skin or eyes and abnormal liver enzymes.

How long will Trypza KP 50mg/325mg Tablet take to act?

It may take about an hour to see the initial benefits of pain relief after taking Trypza KP 50mg/325mg Tablet.

What if I forget to take Trypza KP 50mg/325mg Tablet?

If you forget to take the scheduled dose of Trypza KP 50mg/325mg Tablet and it is almost time for your next dose, skip the dose you missed and take your next dose at the scheduled time. Otherwise, take it as soon as you remember, and then go back to taking your medicine as you would normally. Do not take a double dose to make up for the dose you missed because this may increase the risk of unwanted side effects. If you are not sure what to do, consult your doctor about how to manage situation like this.

Will a higher than the recommended dose of Trypza KP 50mg/325mg Tablet be more effective?

No, taking a higher than the recommended dose may not be more effective, rather it may increase the chances of having some serious side effects and toxicity. If you experience increased severity of your symptoms that are not relieved by the recommended doses, please consult your doctor for re-evaluation.

Are there any specific contraindications associated with the use of Trypza KP 50mg/325mg Tablet?

The use of Trypza KP 50mg/325mg Tablet is considered to be harmful for patients with known allergy to any of the components or excipients of this medicine. The use of this medicine should preferably be avoided in patients with a history of stomach ulcers or in patients with active, recurrent stomach ulcer / bleeding. It should also be avoided in patients with a history of heart failure, high blood pressure, and liver or kidney disease.

What are the instructions for storage and disposal of Trypza KP 50mg/325mg Tablet?

Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Diclofenac sodium [Patient Information Leaflet]. Daventry, Northamptonshire: Dexcel-Pharma Ltd.; 2019. [Accessed 06 Feb. 2020] (online) Available from:
National Health Service. Paracetamol for adults. [Accessed 06 Feb. 2020] (online) Available from:

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