Twin-GM 300mg/500mcg Tablet is a combination medicine used for the treatment of neuropathic pain. This medicine decreases pain by modulating calcium channel activity of the nerve cells.

Twin-GM 300mg/500mcg Tablet is taken by mouth with or without food, preferably at bedtime. It is advised to take medicine at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration advised by your doctor. If you miss a dose of this medicine, take it as soon as you remember. Finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to the doctor.

Some common side effects of this medicine are nausea, peripheral edema, ataxia, blurred vision, fever and nystagmus (involuntary eye movement). It may also cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. It is important to inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts.

Before taking the medicine you should tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding. It can usually be mixed safely with other medicines but some drugs (including antacids and alcohol) do affect the way it works and can increase the chance of side effects.

Uses of Twin-GM Tablet

Treatment of Neuropathic pain

Benefits of Twin-GM Tablet

In Treatment of Neuropathic pain

Twin-GM 300mg/500mcg Tablet is a combination of medicines used to treat long-lasting (chronic) pain caused by nerve damage due to diabetes, shingles or spinal cord injury. It reduces pain and its associated symptoms such as mood changes, sleep problems, and tiredness. It is thought to work by interfering with pain signals that travel through the damaged nerves and the brain. Using this medicine regularly will improve your physical and social functioning and overall quality of life. It takes a few weeks to work so you need to use it regularly even if you feel it is not doing any good. Once your symptoms have gone you should still keep using the medicine until your doctor advises you to stop.

Side effects of Twin-GM Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Twin-GM

Dizziness
Sleepiness
Tiredness

How to use Twin-GM Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Twin-GM 300mg/500mcg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Twin-GM Tablet works

Twin-GM 300mg/500mcg Tablet is a combination of two medicines: Gabapentin and Methylcobalamin. Gabapentin is an alpha 2 delta ligand which decreases pain by modulating calcium channel activity of the nerve cells. Methylcobalamin is a form of vitamin B which helps in the production of myelin, a substance that protects nerve fibers and rejuvenates damaged nerve cells. Together, they relieve neuropathic pain (pain from damaged nerves).

Safety advice

Alcohol

UNSAFE

Twin-GM 300mg/500mcg Tablet may cause excessive drowsiness with alcohol.

Pregnancy

CONSULT YOUR DOCTOR

Twin-GM 300mg/500mcg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Twin-GM 300mg/500mcg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

UNSAFE

Twin-GM 300mg/500mcg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Twin-GM 300mg/500mcg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Twin-GM 300mg/500mcg Tablet may be needed. Please consult your doctor.

Liver

CONSULT YOUR DOCTOR

There is limited information available on the use of Twin-GM 300mg/500mcg Tablet in patients with liver disease. Please consult your doctor.

What if you forget to take Twin-GM Tablet?

If you miss a dose of Twin-GM 300mg/500mcg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Twin-GM 300mg/500mcg Tablet

₹15.0/Tablet

Gabantin Forte Tablet

Sun Pharmaceutical Industries Ltd

₹23/tablet

53% costlier

Acegaba ME 300mg/500mcg Tablet

Emcure Pharmaceuticals Ltd

₹21.83/tablet

46% costlier

Nerwita G 300mg/500mcg Tablet

Saksham Pharmaceuticals India Ltd

₹12.7/tablet

15% cheaper

Gabanyl-M Tablet

Leeford Healthcare Ltd

₹9.3/tablet

38% cheaper

Gabaneuron Tablet

Aristo Pharmaceuticals Pvt Ltd

₹21.2/tablet

41% costlier

View all substitutes

Quick tips

You have been prescribed Twin-GM 300mg/500mcg Tablet for treating and preventing nerve pain.
Its side effects are usually mild and temporary.
It may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
To lower the chances of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
Avoid consuming alcohol when taking Twin-GM 300mg/500mcg Tablet, as it may cause excessive sleepiness.
Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression or suicidal thoughts or behavior.
Do not stop taking the medication suddenly without talking to your doctor.

Fact Box

Habit Forming

Therapeutic Class

NEURO CNS

Patient concerns

I want twin baby which medicine i give to my wife

Dr. Suman Rao

Obstetrics and Gynaecology

There is no med which can guarantee a twin pregnancy

I have so much pain in my head for last 8 years I consult so many but not getting relief ,I am very restless,full of anxiety my brain nerves become so hard please. Please write a medicine

Dr. Aanchal Maheshwari

Ayurveda

mix 100 gm brahmi , 100 gm jatamansi ,50 gm mulethi, 20 gm giloy say10 gm godanti bhasm, 5 gm praval bhasm . 5take above powder 1 spoon twice, Tablet sirah sooll adi vsvati with pathyadi kwath. Tablet cephagrain 2 tablet twice. Pour 1-2 drops of almomd oil in each of your nostril

FAQs

What is Twin-GM 300mg/500mcg Tablet?

Twin-GM 300mg/500mcg Tablet is a combination of two medicines: Gabapentin and Methylcobalamin. This medication is useful in the treatment of pain due to nerve damage (peripheral neuropathy). This medication works by regenerating damaged nerves in the body and decreasing the pain sensation.

What is peripheral neuropathy?

The nerves in the periphery of your body, such as the nerves in your toes and fingertip are called peripheral nerves and any damage to one or more of these nerves is called peripheral neuropathy. These nerves carry messages to/from the brain and spinal cord from/to the rest of the body. A damage caused to these nerves stops them from functioning properly and the messages traveling between your central and peripheral nervous system get disrupted.

Can I stop taking Twin-GM 300mg/500mcg Tablet when my pain is relieved?

No, take Twin-GM 300mg/500mcg Tablet for the full prescribed length of time. Your symptoms may improve before the nerves are completely regenerated and healed.

Can the use of Twin-GM 300mg/500mcg Tablet cause sleepiness?

Yes, the most common side effect of Twin-GM 300mg/500mcg Tablet is sleepiness. Do not drive, operate heavy machinery or engage in other activities that need your full attention. Do not drink alcohol while taking Twin-GM 300mg/500mcg Tablet as it can lead to severe sleepiness , causing falls or accidents.

Can I take a higher than the recommended dose of this medicine?

No, taking a higher than the recommended dose of Twin-GM 300mg/500mcg Tablet can lead to increased chances of side effects and toxicity. If you are experiencing increased severity of your symptoms that are not relieved by the recommended doses, please consult your doctor for re-evaluation.

What is the recommended storage condition for the Twin-GM 300mg/500mcg Tablet?

Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Stahl SM, editor. Gabapentin. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 275-77.
McNamara JO. Pharmacotherapy of the Epilepsies. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 599.
Porters RJ, Meldrum BS. Antiseizure Drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 410.
Combs Jr. GF, McClung JP. The Vitamins: Fundamental Aspects in Nutrition and Health. 5th ed. Westborough, MA: Academic Press; 2017.
PubChem. Methylcobalamin hydrate. [Accessed 22 Apr. 2019] (online) Available from:
Arlak Biotech. Methylcobalamin+gabapentin [Product Information]. [Accessed 14 Aug. 2024] (online) Available from:

Marketer details

Name: Matins Pharma

Address: Office Number 4 & 21 SCO. 3, Sector - 11, Panchkula -134112 Haryana

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.