Valprol 499.50mg/217.50mg Tablet CR is a combination of two medicines used to treat epilepsy, a neurological disorder in which there are recurrent episodes of seizures or fits. It controls the abnormal activity of the brain, relaxes the nerves and hence, prevents seizures or fits.
Valprol 499.50mg/217.50mg Tablet CR should be taken with food. Your doctor will decide the correct dose for you. This may increase gradually until your condition is stable. This medicine may take several weeks to work but it is important to take it regularly to get the benefit. Do not stop taking it, even if you feel fine unless your doctor advises you to. You may have more seizures, or your bipolar disorder may get worse.
The most common side effects of this medicine are nausea and tremor. In some people, it may also cause other side effetcs like vomiting, headache, liver injury, and upper abdominal pain. Most side effects wear off, but if they bother you or do not go away, tell your doctor. There may be ways of preventing or reducing these effects.
Before taking this medicine, tell your doctor if you have kidney or liver problems, meningitis or depression or suicidal thoughts. Also let your doctor know about all other medications you are using as some may affect, or be affected by, this medicine, including contraceptive pills. If you are pregnant or breastfeeding, Valprol 499.50mg/217.50mg Tablet CR can be taken if it is clearly needed but the dose may be adjusted. You should avoid driving or riding a bicycle if this medicine makes you drowsy or dizzy. You may need frequent blood tests to check how you are responding to this medicine.
You should avoid alcohol while taking Valprol 499.50mg/217.50mg Tablet CR, as it may worsen certain side effects. This medicine can also lead to weight gain, eat a healthy balanced diet, avoid snacking with high-calorie food, and exercise regularly. Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts or behavior.
Valprol 499.50mg/217.50mg Tablet CR slows down electrical signals in the brain which cause seizures (fits). It can also help reduce symptoms such as confusion, uncontrollable jerking movements, loss of awareness, and fear or anxiety. The medicine can allow you to do some activities that you would otherwise be forbidden or scared to do (such as swimming and driving). It can take a few weeks for this medicine to work (because the dose has to be increased slowly) and during this time you may still have seizures. Do not stop using this medicine even if you feel well, until your doctor advises you to. Missing doses may trigger a seizure.
Side effects of Valprol Tablet CR
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Valprol
Nausea
Tremors
How to use Valprol Tablet CR
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Valprol 499.50mg/217.50mg Tablet CR is to be taken with food.
How Valprol Tablet CR works
Valprol 499.50mg/217.50mg Tablet CR is a combination of two antiepileptic medicines: Sodium Valproate and Valproic Acid.
Safety advice
Alcohol
UNSAFE
It is unsafe to consume alcohol with Valprol 499.50mg/217.50mg Tablet CR.
Pregnancy
CONSULT YOUR DOCTOR
Valprol 499.50mg/217.50mg Tablet CR is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
SAFE IF PRESCRIBED
Valprol 499.50mg/217.50mg Tablet CR is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Driving
UNSAFE
Valprol 499.50mg/217.50mg Tablet CR may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
SAFE IF PRESCRIBED
Valprol 499.50mg/217.50mg Tablet CR is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Valprol 499.50mg/217.50mg Tablet CR may not be needed in these patients. Please consult your doctor. However, talk to your doctor if you have any underlying kidney disease.
Liver
CAUTION
Valprol 499.50mg/217.50mg Tablet CR should be used with caution in patients with liver disease. Dose adjustment of Valprol 499.50mg/217.50mg Tablet CR may be needed. Please consult your doctor. Use of Valprol 499.50mg/217.50mg Tablet CR is not recommended in patients with severe liver disease and active liver disease.
What if you forget to take Valprol Tablet CR?
If you miss a dose of Valprol 499.50mg/217.50mg Tablet CR, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine
Quick tips
You have been prescribed Valprol 499.50mg/217.50mg Tablet CR for treatment and prevention of seizures.
Take it at the same time every day to maintain consistent levels in your body.
Do not drive or do anything that requires mental focus until you know how Valprol 499.50mg/217.50mg Tablet CR affects you.
Avoid consuming alcohol when taking Valprol 499.50mg/217.50mg Tablet CR, as it may cause excessive sleepiness or drowsiness.
Monitor your weight during the treatment as Valprol 499.50mg/217.50mg Tablet CR can cause weight gain.
Your doctor may monitor Valprol 499.50mg/217.50mg Tablet CR level, blood counts and liver function regularly throughout your treatment. Inform your doctor if you develop fever, stomach pain, nausea or yellowing of your eyes or skin.
Do not take Valprol 499.50mg/217.50mg Tablet CR if you are pregnant or planning to conceive or breastfeeding.
Do not stop taking the medication suddenly without talking to your doctor as it may increase the seizure frequency.
Fact Box
Habit Forming
No
Therapeutic Class
NEURO CNS
Patient concerns
My brother is suffering from conversion disorder what medicine is good for him. Is valprol cr 300 tablets is good for him. Valprol is for epilepsy, can i give this tablets in this problem
Dr. Jyoti Kapoor Madan
Psychiatry
Treatment is based on a number of factors including diagnosis, comorbid condition, severity and duration of symptoms and physiological factors. Please see a psychiatrist for prescription. Usually conversion disorder is due to high levels of anxiety and treatment is for anxiety.
I had epilepsy. Last siezure came on dec 2010 then i consult to a neurologist. He advise me to take VALPROL CR 500 BD n LOBAZAM 10 BD after years dose slowly decreased. Now i m taking valprol cr 200 OD at night. EEG is normal since last 5 years. Please suggest me treatment in ayurveda. Is epilepsy fully treatable in Ayurveda
Dr. Aanchal Maheshwari
Ayurveda
epileptic patient has to be seen personnaly and as per body constitution medicine is adviced, panchkaram is good therapy in ayurveda
I am a epileptic patient, and i have no seizures from hte last 4 years as i am properly following valprol-av-300mg and 500mg medicine, i want to be on gm 7 days diet plan to reduce my weight, can i ? The medicine is valprol-cr-300 and valprol-cr-500 I am a epileptic patient, and i have no seizures from hte last 4 years as i am properly following valprol-cr-300mg and valprol-cr-500mg medicine, i want to be on gm 7 days diet plan to reduce my weight, can i ?
Sunaina Khetarpal
Dietetics/Nutrition
Hi PATIENT weight you loose from GM diet will come back so better to avoid it go for a proper diet plan and walk you can consult me personally at sunainakhetarpal.zest.md
I suffered an epileptic attack about 6 years back. The doctor suggested me take VALPROL CR 750 mg tablet daily twice a day. I am taking the tablets continuously since then and haven't faced any problem till date. I again visited a different doctor 2 years back, he also suggested me to continue with same medicine. I want to ask that should I continue with medicine. If yes then can I take TORVATE 750 MG TABLET in place of Valprol CR 750 because as it is of half price and same composition.
I have ceaser (fit ) problem since 06072014 , Since then I have got one fit and one mild unconsciousness two years back . Since then I am taking medical treatment from PGI Chandigarh. Firstly I was taking Valprol CR and Cloba and Now for the last few months I am taking Valprol Cr 500+300 and Lamictal 200 daily. Is it the Right dose ? And How long I have take the medicine? Please guide.
i am attaching my thyroid test reportt.my t3 and t4 are in high state and tsh in low state.i am on valprol cr 300 for last 3 years .please advice for controlling thyroid.
Dr. Vikas Sharma
Neurology
Start tab neomercazole 5 mg bd Follow with endocrine or physician
Can the use of Valprol 499.50mg/217.50mg Tablet CR cause sleepiness or drowsiness?
Yes, Valprol 499.50mg/217.50mg Tablet CR may make you feel drowsy or sleepy. Avoid driving, operating machinery, working at heights or participating in potentially dangerous activities. Inform your doctor if you experience such an episode while taking this medicine.
Can I drink alcohol while taking Valprol 499.50mg/217.50mg Tablet CR?
No, avoid drinking alcohol while taking Valprol 499.50mg/217.50mg Tablet CR. Drinking alcohol will increase the side effects caused by Valprol 499.50mg/217.50mg Tablet CR.
Can Valprol 499.50mg/217.50mg Tablet CR be stopped when epilepsy symptoms are relieved?
No, Valprol 499.50mg/217.50mg Tablet CR should be continued as advised by the doctor. Stopping Valprol 499.50mg/217.50mg Tablet CR suddenly may cause the symptoms to reappear that too with increased frequency. If any problems are experienced due to Valprol 499.50mg/217.50mg Tablet CR, consult the doctor for re-evaluation.
Will a higher than the recommended dose of Valprol 499.50mg/217.50mg Tablet CR be more effective?
No, taking a higher than the recommended dose may not be more effective, rather it may increase the chances of having serious side effects and toxicity. If the recommended doses do not relieve your symptoms or there is an increased severity of your symptoms, please consult your doctor.
What are the instructions for the storage and disposal of Valprol 499.50mg/217.50mg Tablet CR?
Keep this medicine in the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
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References
Linde M, Mulleners WM, Chronicle EP, et al. Valproate (valproic acid or sodium valproate or a combination of the two) for the prophylaxis of episodic migraine in adults. Cochrane Database Syst Rev. 2013;(6):CD010611. [Accessed 23 Apr. 2019] (online) Available from:
Drugs.com. Sodium Valporate. [Accessed 23 Apr. 2019] (online) Available from:
Drugs.com. Valporic acid. [Accessed 23 Apr. 2019] (online) Available from:
Sodium Valproate and Valproic Acid [Package Information]. Gangtok, Sikkim: TORRENT PHARMACEUTICALS LTD.; 2022. [Accessed 28th Sept. 2023] (online) Available from:
Marketer details
Name: Intas Pharmaceuticals Ltd
Address: Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.