Overview
Uses and benefits
Side effects
How to use
How drug works
Safety advice
Missed dose
All substitutes
Quick tips
Fact box
Interaction with drugs
Patient concerns
User feedback
FAQs

Author Details

Written By

Dr. Anuj Saini

MMST, MBBS

Reviewed By

Dr. Mekhala Chandra

MD, MBBS

Last updated

13 Jan 2026 | 09:26 PM (IST)

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VIBOLIV 300 MG INJECTION

Prescription Required

Marketer

Dr Reddy's Laboratories Ltd

SALT COMPOSITION

Metadoxine (300mg)

Storage

Store below 30°C

Product introduction

VIBOLIV 300 MG INJECTION is an antioxidant medicine used to treat alcoholic fatty liver. It works by protecting the liver from harmful chemical substances and also increases the alcohol elimination from blood and tissues.

VIBOLIV 300 MG INJECTION should be given by the healthcare professional. The dose will depend on what you are being treated for and your body weight. This medicine needs to be taken regularly to get the most benefit and you may have to take it for several months or longer, so try to get into a routine. Keep using it as prescribed even if your symptoms disappear.

The most common side effects are nausea, upset stomach, and diarrhea. Not everyone gets side effects. If you are worried about them, or they do not go away, let your doctor know. If you have problems with diarrhea your doctor may reduce the dose or stop the treatment. Drink enough water or fluids to stay hydrated in case of severe diarrhea.

Before taking this medicine, you should tell your doctor if you are pregnant, planning pregnancy or breastfeeding. Using this medicine can reduce or increase the effect of some other medicines so tell your doctor, all other medicines you are taking.

Uses of Viboliv Injection

Alcoholic fatty liver disease

Benefits of Viboliv Injection

In Alcoholic fatty liver disease

VIBOLIV 300 MG INJECTION belongs to a class of drugs known as hepatoprotectives. It fastens clearance of alcohol from the blood and therefore helps in the treatment of fatty liver due to alcoholism. In the long term, it protects the liver from damage against harmful chemicals known as free radicals, thereby improving the overall health of the liver.

It is given as an injection by your doctor or healthcare provider. Take it in the dose and duration advised by the doctor. To make the medicine more effective and for general health benefits, stop smoking, maintain a healthy weight, and do not drink too much alcohol.

Side effects of Viboliv Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Viboliv

Nausea
Upset stomach
Diarrhea

How to use Viboliv Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Viboliv Injection works

VIBOLIV 300 MG INJECTION is an antioxidant. It works by protecting the liver from harmful chemical substances (free radicals). It also works by increasing alcohol elimination from the blood and tissues, thus preventing liver damage.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with VIBOLIV 300 MG INJECTION. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

The safety of VIBOLIV 300 MG INJECTION during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of VIBOLIV 300 MG INJECTION during breastfeeding is not available. Please consult your doctor.

Driving

CONSULT YOUR DOCTOR

It is not known whether VIBOLIV 300 MG INJECTION alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.

Kidney

CONSULT YOUR DOCTOR

There is limited data available on the use of VIBOLIV 300 MG INJECTION in patients with kidney disease. Please consult your doctor.

Liver

CONSULT YOUR DOCTOR

There is limited data available on the use of VIBOLIV 300 MG INJECTION in patients with liver disease.

What if you forget to take Viboliv Injection?

If you miss a dose of VIBOLIV 300 MG INJECTION, please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

No substitutes found for this medicine

Quick tips

It protects the liver cells from toxins and helps the liver to perform its normal functions.
It is given as an injection under the supervision of a healthcare professional.
Diarrhea may occur as a side effect. Drink plenty of fluids and inform your doctor if diarrhea persists or if you find blood in your stools.

Fact Box

Chemical Class

Pyridoxine derivative

Habit Forming

Therapeutic Class

NEURO CNS

Action Class

Hepatoprotective Agents

Interaction with drugs

Taking Viboliv with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Altretamine (Oral Route) Severe

Do not consume Altretamine with Metadoxine. Metadoxine may reduce the efficacy of Altretamine. It may also reduce Altretamine side effects on the nervous system.

Phenytoin (Oral Route) Moderate

Talk to your doctor if you notice any unusual symptoms.Doctor may monitor your liver function. Metadoxine may raise blood levels of Phenytoin.

Phenytoin (Injection Route) Moderate

Talk to your doctor if you notice any unusual symptoms.Doctor may monitor your liver function. Metadoxine may raise blood levels of Phenytoin.

Levodopa (Oral Route) Moderate

Talk to your doctor if you notice any unusual symptoms. Metadoxine may slow down the removal of Levodopa from the body.

Nitrofurantoin (Oral Route) Mild

Talk to your doctor if you notice any unusual symptoms. Metadoxine may reduce blood levels of Nitrofurantoin.

View all drug interactions

Patient concerns

Fatty liver disease with enlarged liver

Dr. Aanchal Maheshwari

Ayurveda

Take cytozen capsule twice, lavanbhasksr churan half spoon twice

Liver disease due to fatty liver

Dr. Deepak Kumar Soni

Ayurveda

Hi kindly share your reports

I am suffering from liver disorder . Sgpt and sgot is increasing day by day plzz provide solution

Dr. Anshul Varshney

Physician

Hello, Welcome to 1mg. I am Anshul Varshney for your help. Yes your liver enzymes are raised which requires evaluation of the cause. Most common causes of such liver derangement's are Alcohol, Viral hepatitis, Non alcoholic fatty liver disease, Drugs. Since you don't consume any alcohol, so alcohol induced hepatitis is ruled out. So, we should evaluate the other causes, and if no other cause is found, you would require to discuss with your doctor about stopping this drug. I would advise you to get following investigations done: 1. HBsAg for Hepatitis B. 2. Anti HCV Antibody for Hepatitis C. 3. Ultrasound Abdomen. A lot many times, the liver dysfunction is due to Non Alcoholic Fatty Liver Disease (NAFLD). So, if you have any evidence of fatty liver in Ultrasound and your other tests are negative, this rise is liver enzyme would be attributed to NAFLD. For this you need to reduce your weight, reduce fat in diet and if required your doctor may prescribe you Ursedeoxycolic Acid for the same. Make sure that you don't take any pain killers without your doctor's advise. I hope it helps. Stay Healthy

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FAQs

What is VIBOLIV 300 MG INJECTION? What is it used for?

VIBOLIV 300 MG INJECTION belongs to a class of medicines known as hepatoprotective medicines which means that they protect the liver. It is used to treat chronic and acute alcohol intoxication. VIBOLIV 300 MG INJECTION accelerates alcohol clearance from the blood and therefore, also helps in the treatment of fatty liver due to alcoholism.

How does VIBOLIV 300 MG INJECTION work?

VIBOLIV 300 MG INJECTION works by increasing the rate of alcohol clearance from blood and tissues, which leads to faster recovery from alcohol intoxication. This in long term protects the liver from damage against harmful chemicals known as free radicals, thereby improving overall health of the liver.

How to use VIBOLIV 300 MG INJECTION?

VIBOLIV 300 MG INJECTION is given by or under the supervision of a healthcare professional. It should not be self administered. The dose will depend on the condition you are being treated for and your total body weight. Hence it may vary from person to person. Follow your doctor’s instructions carefully to get maximum benefit of VIBOLIV 300 MG INJECTION.

What are the side effects of VIBOLIV 300 MG INJECTION?

The most common side effects associated with VIBOLIV 300 MG INJECTION include nausea, upset stomach and diarrhea. However, these effects are not observed in all patients. If you are worried about them or they do not go away, let your doctor know. If you have problems with diarrhea your doctor may reduce the dose or stop the treatment. Drink enough water or fluids to stay hydrated in case of severe diarrhea.

Can VIBOLIV 300 MG INJECTION be used in pregnancy and lactation?

VIBOLIV 300 MG INJECTION is not advised to be taken by pregnant and breastfeeding women. Consult your doctor before taking VIBOLIV 300 MG INJECTION if you are planning to conceive, pregnant or breastfeeding to prevent harmful effects on the baby.

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Related lab tests

Bilirubin Total

Liver Function Test

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Stefanini GF, Addolorato G, Caputo F, et al. Treatment of alcoholic fatty liver: is the metabolic effect of metadoxine the only reason for improved liver function? J Hepatol. 1999 Apr;30(4):739-40. [Accessed 13 Jan. 2026]. Available from: