Xamfloglip 500mg/2.5mg Tablet
Prescription Required
Product introduction
Xamfloglip 500mg/2.5mg Tablet is a combination of two medicines that control high blood sugar levels in people with type 2 diabetes mellitus. This helps prevent serious complications of diabetes such as kidney damage and blindness and may reduce your chance of having a heart attack or stroke.
Xamfloglip 500mg/2.5mg Tablet can be prescribed alone or together with other diabetes medications. All diabetes medicines work best when used along with a healthy diet and regular exercise. The dose you are given will depend on your condition, blood sugar levels and what other medicines you are taking. Taking it with meals helps to reduce the chances of developing an upset stomach.
You should take it regularly, at the same time each day, to get the most benefit and you should not stop unless your doctor recommends it. It is controlling your blood sugar levels and helping to prevent serious complications in the future. It is important to stay on the diet and exercise program recommended by your doctor while taking this medicine. Your lifestyle plays a big part in controlling diabetes.
The most common side effects of taking this medicine include diarrhea, nausea, vomiting, upset stomach, headache, blocked nose, and sore throat. Low blood sugar level (hypoglycemia) is a possible side effect if you are also taking other diabetes medicines like insulin or sulphonylurea, so you need to know how to recognize and deal with it.
This medicine is not suitable for everyone. Before taking it, you should let your doctor know if you have ever had kidney, liver or heart disease, problems with your pancreas, or if you drink a lot of alcohol. Pregnant or breastfeeding women should also consult their doctor before taking this medicine. Some other medicines can affect this one so tell your doctor about all the medicines you are taking to make sure you are safe. You should try to avoid drinking alcohol as it lowers blood glucose. Your doctor will check your kidney function and blood sugar levels before and during treatment.
Uses of Xamfloglip Tablet
Benefits of Xamfloglip Tablet
In Treatment of Type 2 diabetes mellitus
Xamfloglip 500mg/2.5mg Tablet has two active substances in it i.e. metformin and linagliptin. Metformin belongs to a class of medicines called biguanides. Linagliptin belongs to a group called DPP-4 inhibitors. They work together in different ways to lower your blood glucose levels.
Lowering blood glucose levels is an essential part of managing diabetes. If you can control your blood glucose level, your risk of getting any of the serious complications of diabetes such as kidney damage, eye damage, nerve problems, and loss of limbs is also lowered. Additionally, proper control of diabetes can also reduce the risk of heart disease and stroke. Taking this medicine regularly along with a proper program of diet and exercise will help you live a normal, healthy life. You should keep using this medicine for as long as it is prescribed because it is protecting your future health.
Lowering blood glucose levels is an essential part of managing diabetes. If you can control your blood glucose level, your risk of getting any of the serious complications of diabetes such as kidney damage, eye damage, nerve problems, and loss of limbs is also lowered. Additionally, proper control of diabetes can also reduce the risk of heart disease and stroke. Taking this medicine regularly along with a proper program of diet and exercise will help you live a normal, healthy life. You should keep using this medicine for as long as it is prescribed because it is protecting your future health.
Side effects of Xamfloglip Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Xamfloglip
- Nausea
- Headache
- Hypoglycemia (low blood glucose level)
- Tremors
- Dizziness
How to use Xamfloglip Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Xamfloglip 500mg/2.5mg Tablet is to be taken with food.
How Xamfloglip Tablet works
Xamfloglip 500mg/2.5mg Tablet is a combination of two antidiabetic medicines:.
Safety advice
Alcohol
UNSAFE
It is unsafe to consume alcohol with Xamfloglip 500mg/2.5mg Tablet.
Pregnancy
CONSULT YOUR DOCTOR
Xamfloglip 500mg/2.5mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
UNSAFE
Xamfloglip 500mg/2.5mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
CAUTION
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
Kidney
UNSAFE
Xamfloglip 500mg/2.5mg Tablet is probably unsafe to use in patients with kidney disease and should be avoided. Please consult your doctor.
Liver
UNSAFE
Xamfloglip 500mg/2.5mg Tablet is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.
What if you forget to take Xamfloglip Tablet?
If you miss a dose of Xamfloglip 500mg/2.5mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
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For informational purposes only. Consult a doctor before taking any medicines.
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Quick tips
- Xamfloglip 500mg/2.5mg Tablet should be taken with food to lower the chances of having an upset stomach.
- Take it in addition to regular exercise and a healthy diet to lower the levels of blood sugar.
- Chances of weight gain and low blood sugar are lesser as compared to other diabetes medicines.
- Hypoglycemia (low blood sugar level) may occur when taken along with other antidiabetic medicines, alcohol or on delaying/skipping a meal. Carry a sugar source with you for immediate relief.
- Monitor your blood sugar level regularly while you are taking this medicine.
- Inform your doctor about your diabetes treatment if you are due to have any surgery under a general anaesthetic.
- Tell your doctor immediately if you experience any deep or rapid breathing, persistent nausea, vomiting or stomach pain as Xamfloglip 500mg/2.5mg Tablet may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood.
Fact Box
Habit Forming
No
Therapeutic Class
ANTI DIABETIC
Patient concerns
FAQs
Can the use of Xamfloglip 500mg/2.5mg Tablet cause lactic acidosis?
Yes, the use of Xamfloglip 500mg/2.5mg Tablet can lead to lactic acidosis which is also known as MALA (Metformin-associated lactic acidosis). It is caused by increased levels of lactic acid in the blood. It is a very rare side effect associated with the use of metformin and therefore it is avoided in patients with underlying kidney disease, old age patients or who take large amounts of alcohol. Symptoms of lactic acidosis may include muscle pain or weakness, dizziness, tiredness, feeling of cold in arms and legs, difficulty in breathing, nausea, vomiting, stomach pain or slow heart rate. If you have these symptoms, stop taking Xamfloglip 500mg/2.5mg Tablet and immediately consult your doctor.
What are the possible side effects of Xamfloglip 500mg/2.5mg Tablet?
The use of Xamfloglip 500mg/2.5mg Tablet may cause some common side effects like hypoglycemia (low blood sugar level), altered taste, nausea, stomach pain, diarrhea, and headache. It can also lead to a serious but rare side effect known as lactic acidosis. Additionally, its long-term use can also lead to vitamin B12 deficiency.
Are there any specific conditions in which Xamfloglip 500mg/2.5mg Tablet should not be taken?
The use of Xamfloglip 500mg/2.5mg Tablet should be avoided in patients with known allergy to any of the components of this medicine. The use of this medicine should be avoided in patients with severe kidney impairment, liver impairment, congestive heart failure, lactic acidosis or diabetic ketoacidosis. Therefore, consult your doctor before using Xamfloglip 500mg/2.5mg Tablet.
Is it safe to take alcohol while I am also taking Xamfloglip 500mg/2.5mg Tablet?
No, it is not safe to take Xamfloglip 500mg/2.5mg Tablet along with alcohol. Doing so can increase the chances of lactic acidosis, particularly in cases of fasting, malnutrition or kidney dysfunction. However, if you are not sure, consult your doctor.
What are the instructions for the storage and disposal of Xamfloglip 500mg/2.5mg Tablet?
Keep this medicine in the packet or the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
Can the use of Xamfloglip 500mg/2.5mg Tablet cause hypoglycemia?
The use of Xamfloglip 500mg/2.5mg Tablet does not usually cause hypoglycemia (low blood sugar level) on its own. But, it could occur if there is insufficient supplementation of calories while taking this medicine. Symptoms of hypoglycemia include nausea, headache, irritability, hunger, sweating, dizziness, fast heart rate, and feeling anxious or shaky. The symptoms are more likely to be noticed if you miss or delay your food, drink alcohol, over-exercise or take any other antidiabetic medicine along with it. Hence, regular monitoring of blood sugar level is important. It is recommended to always carry glucose tablets, honey or fruit juice with you.
Can the use of Xamfloglip 500mg/2.5mg Tablet lead to vitamin B12 deficiency?
Yes, long-term use of Xamfloglip 500mg/2.5mg Tablet can cause vitamin B12 deficiency as it interferes with absorption of vitamin B12 in the stomach. If untreated, it may cause anemia and nerve problems. These may further cause a tingling sensation and numbness in hands and feet, weakness, urinary problems, change in mental status and difficulty in maintaining balance (ataxia). Consult your doctor if you experience these symptoms. Your doctor may advise monitoring of B12 levels and prescribe a vitamin B12 supplement if required.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Linagliptin/metformin hydrochloride. Koropi, Greece: Boehringer Ingelheim Ellas A.E.; 2018. [Accessed 28 Jan. 2019] (online) Available from:
- Linagliptin and metformin hydrochloride. Ridgefield, Connecticut: Boehringer Ingelheim Pharmaceuticals, Inc.; 2012. [Accessed 28 Jan. 2019] (online) Available from:
- Metformin hydrochloride. Princeton, New Jersey: Bristol-Myers Squibb Company. [Accessed 08 Apr. 2019] (online) Available from:
- Linagliptin. Ridgefield, Connecticut: Boehringer Ingelheim Pharmaceuticals, Inc.; 2014. (online) [Accessed 08 Apr. 2019] Available from:
- Linagliptin/Metformin hydrochloride tablets [Product monograph]. Ontario, Canada: Boehringer Ingelheim (Canada) Ltd.; 2021. [Accessed 20 Oct. 2021] (online) Available from:
- Linagliptin/Metformin hydrochloride tablets [Product monograph]. Ontario, Canada: Boehringer Ingelheim (Canada) Ltd.; 2019. [Accessed 20 Oct. 2021]. (online) Available from:
- Linagliptin and Metformin Hydrochloride tablets [patient Information Sheet]. Gangtok, Sikkim: TORRENT PHARMACEUTICALS LTD.; 2022. [Accessed 28th Sept. 2023] (online) Available from:
Marketer details
Name: Zenni Pharmaceutical Private Limited
Address: VPO RIRI, TEHSIL JASWAN KOTLA (KANGRA), DISTT. HIMACHAL PRADESH
Country of origin: India
The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.
The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.
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