Xeldrin Injection
Prescription Required
Product introduction
Xeldrin Injection is a medicine that reduces the amount of acid produced in your stomach. It is used for treating acid-related diseases of the stomach and intestine such as acid reflux, peptic ulcer disease, and Zollinger-Ellison syndrome. It provides relief from symptoms and promotes healing.
Xeldrin Injection is also used to prevent stress ulcers in seriously ill patients and is administered before anesthetic medication to help prevent aspiration-related complications. It belongs to a class of medicines known as proton pump inhibitors (PPIs). This medicine is administered into a vein by a healthcare professional and will only be given to you if your doctor thinks that an injection is more suitable for you at the moment than a tablet. The dose will depend on your underlying condition and how you respond to the medicine. Your doctor will decide the duration of treatment but you should keep on taking it as prescribed, even if your symptoms disappear quickly. You can increase the efficiency of the treatment by eating smaller meals more often and avoiding caffeinated drinks (like tea and coffee), and spicy or fatty foods.
The most common side effects observed with this medicine include nausea, headache, flatulence, diarrhea, stomach pain, and injection site reactions (pain, swelling, redness). These symptoms are generally mild but if they bother you or do not go away, consult your doctor. Long-term use of this medicine may lead to an increased risk of side effects. For instance, using this medicine for more than 1 year may increase your risk for bone fractures, especially with higher doses. Talk to your doctor about ways to prevent bone loss (osteoporosis), like taking calcium and vitamin D supplements.
Xeldrin Injection is not suitable for some people. Before taking this medicine, you need to tell your doctor if you have severe liver problems, or have ever had an allergic reaction to similar medicines in the past or suffer from bone loss (osteoporosis).
Many other medicines may affect, or be affected by, this medicine so let your doctor know about all other medicines you are taking, to make sure it is safe. This is particularly important if you are taking medicines for HIV, fungal infections, tuberculosis, epilepsy (fits), or some types of blood thinners.
Pregnant or breastfeeding women should also consult their doctor before taking it. Avoid drinking alcohol as it makes your stomach produce excessive acid and can worsen your symptoms. Do not drive or use machinery or tools, if this medicine makes you feel dizzy or sleepy.
Xeldrin Injection is also used to prevent stress ulcers in seriously ill patients and is administered before anesthetic medication to help prevent aspiration-related complications. It belongs to a class of medicines known as proton pump inhibitors (PPIs). This medicine is administered into a vein by a healthcare professional and will only be given to you if your doctor thinks that an injection is more suitable for you at the moment than a tablet. The dose will depend on your underlying condition and how you respond to the medicine. Your doctor will decide the duration of treatment but you should keep on taking it as prescribed, even if your symptoms disappear quickly. You can increase the efficiency of the treatment by eating smaller meals more often and avoiding caffeinated drinks (like tea and coffee), and spicy or fatty foods.
The most common side effects observed with this medicine include nausea, headache, flatulence, diarrhea, stomach pain, and injection site reactions (pain, swelling, redness). These symptoms are generally mild but if they bother you or do not go away, consult your doctor. Long-term use of this medicine may lead to an increased risk of side effects. For instance, using this medicine for more than 1 year may increase your risk for bone fractures, especially with higher doses. Talk to your doctor about ways to prevent bone loss (osteoporosis), like taking calcium and vitamin D supplements.
Xeldrin Injection is not suitable for some people. Before taking this medicine, you need to tell your doctor if you have severe liver problems, or have ever had an allergic reaction to similar medicines in the past or suffer from bone loss (osteoporosis).
Many other medicines may affect, or be affected by, this medicine so let your doctor know about all other medicines you are taking, to make sure it is safe. This is particularly important if you are taking medicines for HIV, fungal infections, tuberculosis, epilepsy (fits), or some types of blood thinners.
Pregnant or breastfeeding women should also consult their doctor before taking it. Avoid drinking alcohol as it makes your stomach produce excessive acid and can worsen your symptoms. Do not drive or use machinery or tools, if this medicine makes you feel dizzy or sleepy.
Uses of Xeldrin Injection
- Acidity
- Gastroesophageal reflux disease (Acid reflux)
- Peptic ulcer disease
- Treatment of Zollinger-Ellison syndrome
Benefits of Xeldrin Injection
In Treatment of Zollinger-Ellison syndrome
Zollinger-Ellison syndrome is a rare disorder where excessive stomach acid production leads to multiple peptic ulcers. Symptoms include abdominal pain, diarrhea, and heartburn. Xeldrin Injection By reducing the production of stomach acid, it helps alleviate symptoms such as abdominal pain, heartburn, and diarrhea. Esomeprazole also aids in the healing of peptic ulcers, which are common in this condition. By controlling the excessive acid secretion associated with Zollinger-Ellison syndrome, esomeprazole helps improve the overall digestive health and prevents complications such as gastrointestinal bleeding.
Side effects of Xeldrin Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Xeldrin
- Injection site reactions (pain, swelling, redness)
- Diarrhea
- Flatulence
- Headache
- Nausea
- Vomiting
- Abdominal pain
How to use Xeldrin Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Xeldrin Injection works
Xeldrin Injection is a proton pump inhibitor (PPI). It works by reducing the amount of acid in the stomach which helps in relief of acid-related diseases of the stomach and intestine such as acid reflux, peptic ulcer disease, and Zollinger-Ellison syndrome.
Safety advice
Alcohol
UNSAFE
It is unsafe to consume alcohol with Xeldrin Injection.
Pregnancy
SAFE IF PRESCRIBED
Xeldrin Injection is safe to use during pregnancy. Most studies have shown low or no risk to the developing baby.
Breast feeding
SAFE IF PRESCRIBED
Xeldrin Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
CONSULT YOUR DOCTOR
It is not known whether Xeldrin Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
SAFE IF PRESCRIBED
Xeldrin Injection is safe to use in patients with kidney disease. No dose adjustment of Xeldrin Injection is recommended.
Liver
CAUTION
Xeldrin Injection should be used with caution in patients with severe liver disease. Dose adjustment of Xeldrin Injection may be needed. Please consult your doctor.
A lower dose may be advised in patients with liver disease and who have to take this medicine for a long time.
A lower dose may be advised in patients with liver disease and who have to take this medicine for a long time.
What if you forget to take Xeldrin Injection?
If you miss a dose of Xeldrin Injection, please consult your doctor.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
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Quick tips
- It is given as an injection into the vein under the supervision of the doctor.
- Some healthy tips to prevent acidity from happening:
- Avoid excessive intake of carbonated beverages/soft drinks, citrus juices, fried food, caffeinated beverages like tea and coffee.
- Avoid alcohol and smoking.
- Avoid eating late at night or before bedtime.
- Inform your doctor if you get watery diarrhea, fever or stomach pain that does not go away.
- Inform your doctor if you do not feel better after taking it for 14 days as you may be suffering from some other problem that needs attention.
- Do not stop taking medication without talking to your doctor.
- Consult your doctor right away if you develop decreased urination, edema (swelling due to fluid retention), lower back pain, nausea, fatigue, and rash or fever. These could be signs of a kidney problem.
- Xeldrin Injection should be taken 1 hour before a meal, preferably in the morning.
- It is a well-tolerated medicine and provides relief for a long time.
- Some healthy tips to prevent acidity from happening:
- Avoid excessive intake of carbonated beverages/soft drinks, citrus juices, fried food, caffeinated beverages like tea and coffee.
- Avoid alcohol and smoking.
- Avoid eating late at night or before bedtime.
- Inform your doctor if you get watery diarrhea, fever or stomach pain that does not go away.
- Inform your doctor if you do not feel better after taking it for 14 days as you may be suffering from some other problem that needs attention.
- Long-term use of Xeldrin Injection can cause weak bones and a deficiency of minerals such as magnesium. Take adequate dietary intake of calcium and magnesium or their supplements as prescribed by your doctor.
- Consult your doctor right away if you develop decreased urination, edema (swelling due to fluid retention), lower back pain, nausea, fatigue, and rash or fever. These could be signs of a kidney problem.
Fact Box
Chemical Class
Timoprazole Derivative
Habit Forming
No
Therapeutic Class
GASTRO INTESTINAL
Action Class
Proton-Pump Inhibitors
Patient concerns
FAQs
What should I know before taking Xeldrin Injection?
You should not take it if you are taking a medicine containing atazanavir and nelfinavir (used for HIV infection). Let your doctor know if you are suffering from any liver problems, persistent diarrhea or vomiting, black stools (blood-stained stools), unusual weight loss, trouble swallowing, stomach pain or indigestion. Tell your doctor about all the other medicines you are taking because they may affect, or be affected by, this medicine. Inform your doctor if you have or ever had an allergic skin reaction with this medicine. It should not be given to children who are less than 1 year of age or whose body weight is less than 10 kgs. Pregnant and breastfeeding mothers should consult their doctor before taking this medicine to avoid harmful effects on the baby.
Can Xeldrin Injection cause diarrhea?
Yes, it may cause diarrhea as a side effect in some people. This is usually not bothersome, but if you experience persistent watery stools that do not go away, along with stomach cramps and fever, get medical help immediately.
Can Xeldrin Injection be used in cardiac patients?
Patients with cardiac disease can take this medicine as prescribed by the doctor. However, it can interact with certain drugs (e.g clopidogrel, digoxin) which might be used by a patient with an underlying cardiac disease. Patients taking these medicines together need to be monitored closely by a doctor.
Can I take antacids along with Xeldrin Injection?
Yes, you can take antacids 2 hours before or after you take this medicine.
Can Xeldrin Injection cause calcium deficiency and osteoporosis?
It can cause osteoporosis (thinning of bones) as it decreases the calcium absorption leading to calcium deficiency. This leads to an increased risk of bone fractures on long-term use, like hip, wrist or spine fractures. Inform your doctor if you have osteoporosis or if you are taking corticosteroids (these can increase the risk of osteoporosis) before starting your therapy. Consult your doctor on ways to prevent this. Your doctor may advise you calcium or vitamin D supplements to reduce the risk.
Does Xeldrin Injection cause vitamin deficiencies?
It may cause vitamin B12 and vitamin C deficiency. When taken orally, vitamin B12 requires an acidic environment for its absorption from the stomach while this medicine causes a decrease in gastric acid secretion. You may need to take vitamin B12 supplements along with it. The clinical significance of the decrease in vitamin C levels is not known, so vitamin C supplementation is not recommended.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Wallace JL, Sharkey KA. Pharmacotherapy of Gastric Acidity, Peptic Ulcers, and Gastroesophageal Reflux Disease. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman's: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: The McGraw-Hill Companies, Inc.; 2011. [Accessed 24 Jan. 2019] (online) Available from:
- Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Omeprazole. [Updated 2019 Jun 3]. [Accessed 20 Feb. 2020] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). Omeprazole. [Accessed 28 Mar. 2019] (online) Available from:
- Omeprazole [New Zealand Data Sheet]. Lower Hutt, New Zealand: Dr Reddy’s New Zealand Ltd.; 2021. [Accessed 03 Aug. 2023] (online) Available from:
Marketer details
Name: Aci Pharma Pvt Ltd
Address: S402a, School Block, Shakarpur, Delhi - 110092
Country of origin: India
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₹86.4
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MRP₹90 4% OFF
1.0 Injection in 1 vial
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