Xylotin 50mg Injection is used in the treatment of cancer of colon and rectum. It shows its working by stopping or slowing down the growth of cancer cells.
Xylotin 50mg Injection is given as an injection into vein by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
Nausea, fatigue, vomiting, and diarrhea are some common side effects of this medicine. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. It may cause some serious allergic reaction, inform your doctor if you notice sore lips or mouth ulcers, rash, itching and difficulty breathing. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels.
Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. It makes men infertile, hence men should take doctor advice about the freezing of sperm before the treatment. You must avoid driving after taking this medicine as it may cause dizziness.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Xylotin
Abdominal pain
Injection site reaction
Weight gain
Conjunctivitis
Fever
Nosebleeds
Hair loss
Constipation
Skin disorder
Decreased appetite
Infection
Peripheral sensory neuropathy
Inflammation of the nose
Pain
Increased transaminase level in blood
Increased alkaline phosphatase level in blood
Taste change
Edema (swelling)
Lacrimation disorder
Allergic reaction
Fatigue
Nausea
Vomiting
Diarrhea
Stomatitis (Inflammation of the mouth)
Anemia (low number of red blood cells)
Decreased white blood cell count (neutrophils)
Low blood platelets
Headache
Breathlessness
How to use Xylotin Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Xylotin Injection works
Xylotin 50mg Injection is an anti-cancer medication. It works by damaging the genetic material (DNA and RNA) of the cancer cells which stops their growth and multiplication.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Xylotin 50mg Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Xylotin 50mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
UNSAFE
Xylotin 50mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
UNSAFE
Xylotin 50mg Injection may cause side effects which could affect your ability to drive. Xylotin 50mg Injection treatment may result in an increased risk of dizziness, nausea, and vomiting, and other neurological symptoms that affect walking and this may affect your ability to drive.
Kidney
CAUTION
Xylotin 50mg Injection should be used with caution in patients with severe kidney disease. Dose adjustment of Xylotin 50mg Injection may be needed. Please consult your doctor. Limited information is available on the use of Xylotin 50mg Injection in these patients. No dose adjustment is recommended in patients with mild to moderate kidney disease.
Liver
CAUTION
Xylotin 50mg Injection should be used with caution in patients with liver disease. Dose adjustment of Xylotin 50mg Injection may be needed. Please consult your doctor.
What if you forget to take Xylotin Injection?
If you miss a dose of Xylotin 50mg Injection, please consult your doctor.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
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I hv phobia of cancer plzzzzzz I m suffering from mild stomach pain change in bowel movement and lack of apputite and i m depressed to thik about that it s a some type of cancer like stonach cancer or colon cancer All day i think about cancer in my body
Diagnosed with colon cancer 30 by 40 mm. There is also lump near liver, how ever it could not be verified whether it is benign or malign. Please suggest the way to diagnose the tumour near liver and also the treatment and cost to cure colon cancer
Dr. Vijay Sharnangat
Medical Oncology and Hematology
Do only pet scan , it will guide.Needs chemotherapy followed by surgery
no as such home remedy to treat colon cancer, case has to be first seen, before prescribing medicine. Giloy ras. wheat grass juice, aamal ras, neem ras, cow urine , each 20 ml twice is helpful
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1689-90.
Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 944.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1034-35.
Oxaliplatin. Hayes, UK: Ranbaxy (UK) Limited a Sun Pharmaceutical Company; 2011 [19 Apr. 2018]. [Accessed 22 Jan. 2019] (online) Available from:
Oxaliplatin. Bridgewater, New Jersey: sanofi-aventis U.S; 2002 [revised Oct. 2015]. [Accessed 26 Mar. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 26 Mar. 2019] (online) Available from: