Zacroli Forte 0.1% Ointment is used to treat eczema (atopic dermatitis). It works by suppressing the activity of certain immune cells that cause inflammation (redness and swelling) of the skin. This relieves itching and improves rashes in atopic dermatitis.

Zacroli Forte 0.1% Ointment is used for external use. It should be used 2-4 times a day on the affected area or use it as suggested by the doctor. It should be applied slowly and evenly to the skin until it is rubbed in. You should not use it too often and you should not cover the treated area with a bandage or plaster. You must inform your doctor if there’s no improvement even after two weeks of treatment or if the skin gets worse.

Use of this medicine may cause some common side effects like erythema, headache, inflammation of hair follicle, and application site reaction like burning, irritation, itching, and redness. This medicine is not normally recommended during pregnancy or while breastfeeding unless it is clearly needed.

Uses of Zacroli Ointment

Treatment of Atopic dermatitis

Benefits of Zacroli Ointment

In Treatment of Atopic dermatitis

Atopic dermatitis, also known as eczema, is a chronic skin condition causing red, itchy, and inflamed patches on the skin, often associated with allergies. Zacroli Forte 0.1% Ointment when applied topically suppresses the immune response in the skin, reducing the inflammatory reactions that lead to eczema flare-ups. This way it provides relief and helps improve the quality of life for individuals with atopic dermatitis.

Side effects of Zacroli Ointment

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Zacroli

Application site reactions (burning, irritation, itching and redness)
Headache
Hair follicle inflammation

How to use Zacroli Ointment

This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and gently massage the ointment.

How Zacroli Ointment works

Zacroli Forte 0.1% Ointment is an immunosuppressant. It works by suppressing the activity of certain immune cells that cause inflammation (redness and swelling) of the skin. This relieves itching and improves rashes in atopic dermatitis.

Safety advice

Alcohol

No interaction found/established

Pregnancy

CONSULT YOUR DOCTOR

Zacroli Forte 0.1% Ointment may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

SAFE IF PRESCRIBED

Zacroli Forte 0.1% Ointment is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Driving

No interaction found/established

Kidney

No interaction found/established

Liver

No interaction found/established

What if you forget to take Zacroli Ointment?

If you miss a dose of Zacroli Forte 0.1% Ointment, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Zacroli Forte 0.1% Ointment

₹38.6/gm of Ointment

Tacroz Forte Ointment

Glenmark Pharmaceuticals Ltd

₹53/gm of ointment

37% costlier

Tacroz Forte Ointment

Glenmark Pharmaceuticals Ltd

₹38.95/gm of ointment

1% costlier

T-Top Forte Ointment

Wallace Pharmaceuticals Pvt Ltd

₹66.1/gm of ointment

71% costlier

Tacroz Forte XL Ointment

Glenmark Pharmaceuticals Ltd

₹24.28/gm of ointment

37% cheaper

Pangraf 0.1% Ointment

Mankind Pharma Ltd

₹38.1/gm of ointment

1% cheaper

View all substitutes

Quick tips

Zacroli Forte 0.1% Ointment is effective at treating eczema (atopic dermatitis) when other treatment options have failed.
It works by decreasing itching, redness, and skin rashes.
Apply thinly, to affected areas of skin only. Clean the affected area and dry well before applying Zacroli Forte 0.1% Ointment. Avoid contact with water after application.
Inform your doctor if there's no improvement even after two weeks of treatment, or if the skin gets worse.
Don't cover the area being treated with airtight dressings such as bandages unless directed by a doctor, as this may increase the risk of side effects.
Stop using Zacroli Forte 0.1% Ointment and consult your doctor if your eczema becomes infected.
Continuous long-term use of the ointment should be avoided. Use as prescribed by you doctor.

Fact Box

Chemical Class

Macrolide Lactams

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Immunosuppressant- Calcineurin inhibitors

Patient concerns

Suffering from Atopic dermatitis 15months baby suffering from atopic dermatitis

Dr. Gopal Bansilal Samdani

Paediatrics

Please consult skin specialist

Suffering from severe atopic dermatitis

Dr. Saurav Arora

Homeopathy

Dear sir atopic dermatitis needs supervision and regular follow up, therefore, you need to visit a homeopath personally

Allergic rashes develop in body every week My son is only 2 year and 4 month old, he is very much suffering from allergic rashes over last one year We are looking for a permanent solution for this problem. We are consulting the skin specialist over one but when medicine is stop, Allergies growing between 4 to 7 daysy

Dr. Atul Jain

Dermatology

Your child may hav atopic dermatitisTake care of skin with moisturizer, use baby soap

What is the treatment for atopic dermatitis?

Dr. Souvik Sardar

Dermatology

Hello PATIENT moisturiser is the pillar for treatment of ADApply non irritant moisturiser better to use ceramide rich oneIf there is any inflammation then anti inflammatory creams like topical steroid or calcineurin inhibitors are usePhototherapy is also an effective modalityBt wch one ti choose depends solely on the status of the disease and to ascertain that a gud examination and history taking with face to face consultation is reqdNw a days vit d3 is also used in AD so also cyclosporine. there r numerous therapeutic modalities bt as I said treatment is alwyz individualised

FAQs

What is Zacroli Forte 0.1% Ointment used for?

Zacroli Forte 0.1% Ointment is a medicine that modulates the immune system. It works on the immune system and mostly decreases its activity. It is used to treat moderate to severe eczema (atopic dermatitis) in adults who do not respond to steroids or develop side effects on using them. In atopic dermatitis, the skin’s immune system undergoes an overreaction and causes skin inflammation leading to itchiness, redness and dryness. Zacroli Forte 0.1% Ointment acts on the abnormal immune response and alters it, thereby relieving the skin inflammation and itchiness.

What are the side effects of Zacroli Forte 0.1% Ointment?

Zacroli Forte 0.1% Ointment, when applied to the skin, may cause skin irritation, burning sensation and itching at the site of application. These are usually mild to moderate in severity and normally resolve within one week of starting the treatment. Redness is also a common manifestation along with sensation of warmth, pain, altered sensation and rash at the site of application. Using it increases the patients’ increased risk of getting inflamed or infected hair follicles, cold sores, acne and generalized herpes simplex infections.

Is Zacroli Forte 0.1% Ointment ointment safe?

As compared to other immune-suppressing medicines, Zacroli Forte 0.1% Ointment has been found to be a safe and effective short-term treatment for atopic dermatitis. When applied on the affected part of the skin, its absorption to the blood and body is minimal. Hence, the side effects are less as compared to when taken through oral route.

Does Zacroli Forte 0.1% Ointment has abuse potential?

No, Zacroli Forte 0.1% Ointment does not have abuse potential and thus, is not a controlled substance. Controlled substances have potential for abuse so they need permission by authorities and doctor for use.

Does Zacroli Forte 0.1% Ointment cause cancer?

Long-term use of Zacroli Forte 0.1% Ointment has been found to have increased risk of lymph node tumors called lymphoma. Some studies have found that few patients who used Zacroli Forte 0.1% Ointment ointment or another similar medication developed skin cancer or lymphoma. Consult your doctor if you have to use Zacroli Forte 0.1% Ointment ointment for more than 6 weeks or if your eczema symptoms have not improved or are getting worse with time during your treatment.

Is Zacroli Forte 0.1% Ointment a steroid?

No, Zacroli Forte 0.1% Ointment is not a steroid. It is a medicine which modulates the working of the immune system. It is used in the treatment of eczema, most commonly in atopic dermatitis. An advantage of Zacroli Forte 0.1% Ointment is that it does not cause skin thinning (atrophy) or other steroid-related side effects.

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References

Burkhart C, Morrell D, Goldsmith L. Dermatological Pharmacology. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1822.
Lake DF, Briggs AD, Akporiaye ET. Immunopharmacology. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 972.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1305-309.
Tacrolimus monohydrate. Hurley, Berkshire: Leo Laboratories Limited; 2002 [revised 30 Jun. 2018]. [Accessed 17 Apr. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 06 Apr. 2019] (online) Available from:
Tacrolimus [Prescribing Information]. Dublin 12, Ireland: LEO Laboratories Ltd.; 2022. [Accessed 01 Aug. 2023]. (online) Available from:

Marketer details

Name: Solace Biotech Ltd

Address: 80 , HSIDC , Industrial Area , Near Jagadhri Road, Ambala Cantt ( Haryana) , Pin Code-(133001), India

Country of origin: India

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