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MD Pharmacology, MBBS
Last updated
07 Nov 2024 | 01:02 AM (IST)

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Zibutol INH 300mg/800mg Tablet

Prescription Required

Product introduction

Zibutol INH 300mg/800mg Tablet is a combination medicine used in the treatment of tuberculosis. It prevents the growth of the microorganisms that cause the infection.

Zibutol INH 300mg/800mg Tablet is a prescription medicine and it is to be taken it as suggested by the doctor. It should be taken in an empty stomach and take it at a fixed time to ensure better efficacy. Do not consume more than the recommended dose, as this may have harmful effects on your body. If you miss a dose, take it as soon as you remember. The course of the treatment must be completed even if you feel better. Sudden discontinuation of the treatment may affect the potency of the medicine. The medicine may take some to show its effects on the symptoms. However, it is advised to consult the doctor if you feel an aggravation of the condition or if your condition does not improve.

Some common side effects of this medicine are nausea, vomiting, fever, dark-colored urine, sweating, increased saliva, etc. To cope up with the side effects, you should drink plenty of water. If any of the side effects get aggravated, you must consult your doctor immediately. Generally, serious side effects are rare. If you experience any allergic reaction (rashes, itching, swelling, shortness of breath, etc.), you must seek immediate medical help.

Before taking this medicine, you should tell your doctor if you are taking any medicines for any health condition. Patients with liver and kidney ailments must take this medicine with proper consultation and caution. Pregnant or breastfeeding women should also consult with the doctor before taking it. Avoid drinking alcohol as it can cause excessive drowsiness with this medicine. It usually does not impair your ability to drive, but you should not drive if it makes you feel sleepy or dizzy. During the treatment, you must take adequate rest and eat a healthy diet for a faster recovery. While on the medication, your doctor may ask for a few laboratory and diagnostic tests to know the effects of the medicine on your body.

Uses of Zibutol INH Tablet

Benefits of Zibutol INH Tablet

In Treatment of Tuberculosis (TB)

Tuberculosis is an infectious disease that mainly affects the lungs but can affect other parts of the body as well. Zibutol INH 300mg/800mg Tablet helps treat tuberculosis by stopping the growth of bacteria causing infection. Your symptoms might improve after using Zibutol INH 300mg/800mg Tablet. However, make sure to complete the full course of treatment. This will ensure that the infection is completely cured and prevent it from returning.

Side effects of Zibutol INH Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Zibutol INH

  • Peripheral neuropathy (tingling and numbness of feet and hand)
  • Increased liver enzymes
  • Jaundice
  • Increased uric acid level in blood
  • Gout
  • Visual impairment

How to use Zibutol INH Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Zibutol INH 300mg/800mg Tablet is to be taken empty stomach.
Avoid Zibutol INH 300mg/800mg Tablet with tyramine-rich food such as cheese, smoked fish, meats and some types of beer.

How Zibutol INH Tablet works

Zibutol INH 300mg/800mg Tablet is a combination of two medicines: isoniazid and ethambutol which treat tuberculosis. Isoniazid prevents the TB bacteria from forming their own protective covering. This kills the bacteria and eradicate the infection. Ethambutol, on the other hand works by slowing the growth of these bacteria.

Safety advice

Alcohol
UNSAFE
Consuming alcohol while taking Zibutol INH 300mg/800mg Tablet may cause symptoms such as flushing, increased heart beat, nausea, thirst, chest pain and low blood pressure (Disulfiram reaction).
Pregnancy
CONSULT YOUR DOCTOR
Zibutol INH 300mg/800mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
SAFE IF PRESCRIBED
Zibutol INH 300mg/800mg Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Driving
UNSAFE
Zibutol INH 300mg/800mg Tablet may cause side effects which could affect your ability to drive.
Zibutol INH 300mg/800mg Tablet occasionally causes sight problems and tingling or numbness in hand or feet. After taking this medicine you should not drive until you know how it affects you.
Kidney
CAUTION
Zibutol INH 300mg/800mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Zibutol INH 300mg/800mg Tablet may be needed. Please consult your doctor.
Kidney function tests are advisable before the start of this medicine.
Liver
CAUTION
Zibutol INH 300mg/800mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Zibutol INH 300mg/800mg Tablet may be needed. Please consult your doctor.

What if you forget to take Zibutol INH Tablet?

If you miss a dose of Zibutol INH 300mg/800mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Zibutol INH 300mg/800mg Tablet
₹4.28/Tablet
₹12.3/tablet
187% costlier
Myconex 800 Tablet
Cadila Pharmaceuticals Ltd
₹15.2/tablet
255% costlier
Econex 300mg/800mg Tablet
Macleods Pharmaceuticals Pvt Ltd
₹13/tablet
204% costlier
Iso Koxi 300 mg/800 mg Tablet
Shreya Life Sciences Pvt Ltd
₹9.38/tablet
119% costlier
₹6.52/tablet
52% costlier

Quick tips

  • Zibutol INH 300mg/800mg Tablet should be taken on an empty stomach but at the same time every day.
  • Do not skip any doses and finish the full course of treatment even if you feel better.
  • It may cause dizziness. Don't drive or do anything that requires mental focus until you know how Zibutol INH 300mg/800mg Tablet affects you.
  • It is advisable to stay hydrated and drink plenty of water to overcome medicine side effects.
  • Avoid consuming alcohol while taking this medication as it can enhance the dizziness.
  • Your doctor may monitor your liver function, vision and thyroid function while on treatment with this medicine.

Fact Box

Habit Forming
No
Therapeutic Class
ANTI INFECTIVES

Patient concerns

arrow
My daughter is given tb medicine even though she is not infected taking these medicine will cause tb???
Dr. Rahul Yadav
Paediatrics
Hello, TB medicines are given only when there is indication of tuberculosis. They are for treating tuberculosis.
Extra pulmonary tuberculosis mdr tb for spinal card treatment
Dr. Sunil Sekhri
Diabetology
This needs to be examined and treated in the clinic
arrow

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Gumbo T. Chemotherapy of Tuberculosis, Mycobacterium Avium Complex Disease, and Leprosy. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman's: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: The McGraw-Hill Companies, Inc.; 2011. [Accessed 09 Apr. 2019] (online) Available from:External Link
  2. Ethambutol. Ontario, Canada: Patheon Inc.; 2007. [Accessed 09 Apr. 2019] (online) Available from:External Link
  3. Isoniazid. Nottingham, Nottinghamshire: Boots Contract Manufacturing; 2015. [Accessed 09 Apr. 2019] (online) Available from:External Link
  4. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-98. [Accessed 09 Apr. 2019] (online) Available from:External Link

Marketer details

Name: Mexon Healthcare Ltd
Address: 69 GREEN PARKAMBLI BOPAL AHMEDABAD Ahmedabad GJ 000000 IN , - , .
Country of origin: India

NOT FOR SALE
We do not facilitate sale of this product at present

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