Zifro 500mg Tablet is an antibiotic used to treat various types of bacterial infections of the respiratory tract, ear, nose, throat, lungs, skin, and eye in adults and children. It is also effective in typhoid fever and some sexually transmitted diseases like gonorrhea.

Zifro 500mg Tablet is taken orally, preferably one hour before or 2 hours after a meal. It should be used regularly at evenly spaced time intervals as prescribed by your doctor. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping the medicine too early may lead to the return or worsening of the infection.

Commonly seen side effects seen with this medicine include vomiting, nausea, stomach pain, headache, and diarrhea. These are usually temporary and subside with the completion of treatment. Consult your doctor if you find these side effects worry you or persist for a longer duration.

Do not use Zifro 500mg Tablet if you have a history of cholestatic jaundice or hepatic dysfunction that happened with the use of azithromycin. Inform your doctor if you have any previous history of allergy or heart problems before taking this medicine. Pregnant or breastfeeding women should consult their doctor before using this medicine.

Uses of Zifro Tablet

Treatment of Bacterial infections

Benefits of Zifro Tablet

In Treatment of Bacterial infections

Zifro 500mg Tablet is an antibiotic medicine that can be used to treat many different infections caused by bacteria. These include infections of the blood, brain, lungs, bones, joints, urinary tract, stomach, and intestines. It can also be used to treat sexually transmitted diseases. It stops the growth of the bacteria causing the infection and clears the infection. Take it for as long as prescribed by the doctor and avoid skipping doses. This will make sure that all bacteria are killed and they do not become resistant.

Side effects of Zifro Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Zifro

Diarrhea
Headache
Nausea
Abdominal pain

How to use Zifro Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Zifro 500mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Zifro Tablet works

Zifro 500mg Tablet is an antibiotic. It works by preventing synthesis of essential proteins required by bacteria to carry out vital functions. Thus, it stops the bacteria from growing, and prevents the infection from spreading.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Zifro 500mg Tablet.

Pregnancy

SAFE IF PRESCRIBED

Zifro 500mg Tablet is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Breast feeding

SAFE IF PRESCRIBED

Zifro 500mg Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
There may be a possibility of diarrhea or rash in the baby.

Driving

SAFE

Zifro 500mg Tablet does not usually affect your ability to drive.

Kidney

CAUTION

Zifro 500mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Zifro 500mg Tablet may be needed. Please consult your doctor.

Liver

CAUTION

Zifro 500mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Zifro 500mg Tablet may be needed. Please consult your doctor.

What if you forget to take Zifro Tablet?

If you miss a dose of Zifro 500mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Zifro 500mg Tablet

₹21.8/Tablet

Azax 500 Tablet

Sun Pharmaceutical Industries Ltd

₹20.33/tablet

7% cheaper

Azikem 500mg Tablet

Alkem Laboratories Ltd

₹19.67/tablet

10% cheaper

Zithrolect 500 Tablet

Abbott

₹19.67/tablet

10% cheaper

Azithral 500 Tablet

Alembic Pharmaceuticals Ltd

₹25.6/tablet

17% costlier

Azicip 500 Tablet

Cipla Ltd

₹23/tablet

6% costlier

View all substitutes

Quick tips

Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early may make the infection to come back and harder to treat.
Take it 1 hour before or two hours after food.
Do not take antacids 2 hours before or after taking Zifro 500mg Tablet.
Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it doesn't stop or if you find blood in your stools.
Stop taking Zifro 500mg Tablet and inform your doctor immediately if you develop an itchy rash, swelling of the face, throat or tongue or breathing difficulties while taking it.

Fact Box

Chemical Class

Macrolides

Habit Forming

Therapeutic Class

ANTI INFECTIVES

Action Class

Macrolides

Interaction with drugs

Taking Zifro with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Domperidone (Oral Route) Life-threatening

Concomitant use may affect heart rhythm and can be fatal. Do not consume Domperidone with Azithromycin.

Amiodarone (Oral Route) Severe

Concurrent use may cause serious disturbance in heart rhythm. Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart... More

Amiodarone (Injection Route) Severe

Concurrent use may cause serious disturbance in heart rhythm. Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart... More

Arsenic Trioxide (Injection Route) Severe

Concurrent use may cause serious disturbance in heart rhythm. Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart... More

Artemether (Injection Route) Severe

Concurrent use may cause serious disturbance in heart rhythm. Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart... More

View all drug interactions

Patient concerns

Scar on face due to bacterial infections

Dr. Atul Jain

Dermatology

Pic is not clear, plz visit for proper opinion

I have a history of recurring yeast and bacterial vaginosis infections.

Dr. Sonu Balhara Ahlawat

Obstetrics and Gynaecology

Tab metrogyl 500 mg twice a day x 5 days and tab fluconazole 150 mg three doses alternate days

User feedback

What are you using Zifro Tablet for?

Bacterial inf*

60%

Others

40%

*Bacterial infections

How much was the improvement?

Average

67%

Poor

33%

What were the side-effects while using Zifro 500mg Tablet?

No Side Effec*

100%

*No Side Effect

How do you take Zifro Tablet?

With food

100%

Please rate Zifro 500mg Tablet on price

Average

67%

Not Expensive

33%

FAQs

Is Zifro 500mg Tablet safe?

Zifro 500mg Tablet is safe if used at prescribed doses for the prescribed duration as advised by your doctor.

What if I don't get better?

You should inform your doctor if you do not notice any improvement in your symptoms after 3 days of taking Zifro 500mg Tablet. Also, if your symptoms get worse, inform your doctor immediately.

Can the use of Zifro 500mg Tablet cause diarrhea?

Yes, the use of Zifro 500mg Tablet can cause diarrhea. It is an antibiotic which kills the harmful bacteria. However, it also affects the helpful bacteria in your stomach or intestine and causes diarrhea. If you are experiencing severe diarrhea, talk to your doctor about it.

Can Zifro 500mg Tablet be taken at night?

Zifro 500mg Tablet is usually prescribed once daily. You can take it at any time of the day, but remember to take it at the same time each day. The medicine should be taken 1 hour before meals or 2 hours after eating food. You can take the tablet preparation with or without food. However, you must take Zifro 500mg Tablet exactly as advised by your doctor and ask your doctor if you have any doubts.

How long does it take Zifro 500mg Tablet to work?

Zifro 500mg Tablet starts working within a few hours of taking it. You may notice an improvement in symptoms after a few days. Do not stop taking the medicine without completing the course mentioned by your doctor. Stopping the medicine without consulting your doctor may cause the infection to come back which may be more difficult to treat.

Why is Zifro 500mg Tablet given for 3 days?

The duration of treatment depends on the type of infection being treated and the age of the patient. Zifro 500mg Tablet is not necessarily given for 3 days. In most bacterial infections, a single dose of 500 mg is given for 3 days. Alternatively, it can be given as 500 mg once on day 1 and then 250 mg once from day 2 to day 5. In some cases of infection such as genital ulcer disease, it is given as a single 1 gram dose. Therefore, you must stick to the regime advised by your doctor.

What should I avoid while taking Zifro 500mg Tablet?

Generally, it is recommended that patients taking Zifro 500mg Tablet should avoid taking any antacid with this medicine as this can affect the overall effectiveness of Zifro 500mg Tablet. It is also recommended to avoid exposure to sunlight or tanning beds as Zifro 500mg Tablet increases the risk of sunburn.

Is Zifro 500mg Tablet a strong antibiotic?

Zifro 500mg Tablet is an effective antibiotic that is used for the treatment of many bacterial infections. Compared to other antibiotics, Zifro 500mg Tablet has a longer half-life which means that it stays in the body for a long time because of which it is given once a day and for a short span of time. Other antibiotics comparatively have a shorter half-life and are usually given twice, thrice, or four times a day.

Can you get a yeast infection from taking Zifro 500mg Tablet?

Some people may get a fungal or yeast infection known as thrush after taking Zifro 500mg Tablet. Antibiotics such as Zifro 500mg Tablet can kill the normal or ‘good bacteria’ of your intestine responsible for preventing thrush. You should inform your doctor if you get a sore or vaginal itching or discharge. Also, inform your doctor if you get a white patch in the mouth or tongue after taking Zifro 500mg Tablet or soon after stopping it.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Chambers HF, Deck DH. Tetracyclines, Macrolides, Clindamycin, Chloramphenicol, Streptogramins, & Oxazolidiones. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 801.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 117-20.
Azithromycin. Frimley, Camberley: Sandoz Ltd.; 2006 [revised 31 Aug. 2018]. [Accessed 31 Mar. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 31 Mar. 2019] (online) Available from:
Azithromycin [Prescribing Information]. Panchmahal, Gujarat: Alembic Pharmaceuticals Limited; 2019. [Accessed 09 Jun, 2023] (online) Available from:

Marketer details

Name: Laenor Pharmaceuticals

Address: 38, Shiv Nagar-2, Opp. Suresh Bandhu Chemicals, Batala Road, Amritsar - 143001.

Country of origin: India

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