Zione DS O 20mg/12.5mg Tablet is a combination of two medicines. It helps to control high blood pressure in different ways. If high blood pressure is not treated it can lead to heart attacks, strokes and kidney failure.

You can take Zione DS O 20mg/12.5mg Tablet with or without food. The dose will depend on your condition and how you respond to the medicine. Try to take it at the same time each day. It is important to keep taking this medicine until your doctor tells you not to. It contains a diuretic (water pill) and will make you urinate more so, it is best to avoid taking this medicine within four hours of going to bed. Use this medicine regularly to get the most benefit from it even if you feel well. High blood pressure does not usually have symptoms and if you stop taking it your risk of heart attack or stroke may increase.

The most common side effect is dizziness. Other side effects include feeling tired, nausea, diarrhea, headache, and decreased blood pressure. Frequent urination is not a side effect of this medicine. It is the purpose of chlorthalidone and helps control your blood pressure. You may experience other possible side effects, but most are rare. Make sure you read the leaflet that comes with your medicines and tell your doctor if you are bothered by side effects or they do not go away. It may be possible to adjust your dose or try a different medicine.

This medicine is not recommended during pregnancy and you should ask your doctor before taking it if you have kidney or liver disease, heart trouble or diabetes. Drinking alcohol can further lower your blood pressure and may cause side effects.

Uses of Zione DS O Tablet

Hypertension (high blood pressure)

Benefits of Zione DS O Tablet

In Hypertension (high blood pressure)

Zione DS O 20mg/12.5mg Tablet is a combination of two medicines namely Olmesartan and chlorthalidone. It is generally used when one medicine alone is not controlling your blood pressure effectively. Olmesartan works by relaxing and widening your blood vessels so your blood can flow more easily. This will lower your blood pressure. Chlorthalidone is known as a diuretic (water pill) which increases urine output thereby lowering blood pressure. If your blood pressure is controlled you are less at risk of having a heart attack, stroke, or kidney problems. The medicine must be taken regularly as prescribed to be effective. You do not usually feel any direct benefit from taking this medicine, but it works in the long term to keep you well.

Side effects of Zione DS O Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Zione DS O

Nausea
Taste change
Diarrhea
Upset stomach
Weakness
Headache
Increased blood uric acid
Dizziness
Increased blood lipid level
Electrolyte imbalance
Decreased blood pressure
Urinary tract infection
Renal dysfunction
Sore throat
Abnormal liver function tests
Increased potassium level in blood

How to use Zione DS O Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Zione DS O 20mg/12.5mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Zione DS O Tablet works

Zione DS O 20mg/12.5mg Tablet is a combination of two medicines:.

Safety advice

Alcohol

UNSAFE

Zione DS O 20mg/12.5mg Tablet may cause excessive drowsiness with alcohol.

Pregnancy

CONSULT YOUR DOCTOR

Zione DS O 20mg/12.5mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Zione DS O 20mg/12.5mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

UNSAFE

Zione DS O 20mg/12.5mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Zione DS O 20mg/12.5mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Zione DS O 20mg/12.5mg Tablet may be needed. Please consult your doctor.
Use of Zione DS O 20mg/12.5mg Tablet is not recommended in these patients.

Liver

CAUTION

Zione DS O 20mg/12.5mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Zione DS O 20mg/12.5mg Tablet may be needed. Please consult your doctor.
Use of Zione DS O 20mg/12.5mg Tablet is not recommended in patients with severe liver disease.

What if you forget to take Zione DS O Tablet?

If you miss a dose of Zione DS O 20mg/12.5mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Zione DS O 20mg/12.5mg Tablet

₹10.1/Tablet

Olmin 20-CH Tablet

Eris Lifesciences Ltd

₹16.1/tablet

59% costlier

Olsar CH 20mg/12.5mg Tablet

Torrent Pharmaceuticals Ltd

₹14.3/tablet

42% costlier

Olsertain-CT 20 Tablet

Dr Reddy's Laboratories Ltd

₹15.5/tablet

53% costlier

Olmin 20 CH Tablet

Eris Lifesciences Ltd

₹17.27/tablet

71% costlier

Olmezest CH 20 Tablet

Sun Pharmaceutical Industries Ltd

₹16.3/tablet

61% costlier

View all substitutes

Quick tips

You have been prescribed Zione DS O 20mg/12.5mg Tablet for the treatment of high blood pressure.
It can be taken with or without food.
Zione DS O 20mg/12.5mg Tablet may cause dehydration. Drink plenty of fluids and inform your doctor if you develop extreme thirst, very dry mouth or muscle weakness.
It may cause dizziness. Get up slowly when rising from a sitting or lying position.
Use of Zione DS O 20mg/12.5mg Tablet during pregnancy or breastfeeding is unsafe.
It may also decrease the risk of stroke and heart attacks.

Fact Box

Habit Forming

Therapeutic Class

CARDIAC

Patient concerns

I am a patient of hypertension

Dr. Jyoti Kapoor Madan

Psychiatry

Hypertension is clinal condition of high blood pressure. Please see a physician.

Some times I had lot of hypertension

Dr. Jyoti Kapoor Madan

Psychiatry

Hypertension is clinically high blood pressure. Persistent high arterial blood pressure above 120/80 mm HG is termed as pre-hypertension or hypertension, but the point to be emphasized is that this rise in blood pressure is persistent. Transient increase in BP occurs in stress and anxiety and needs to be treated accordingly.

I'm type 2 diabetic patient with hypertension, l am taking following medicines Tezloc 40 - OD Glimisave Max-1 forte. BBF Glimisave Max-2 forte Cd Rozavel -5. Hs My usual blood pressure -80/145 Usual Blood glucose levels :fasting -120 PP-180 Hba1c - 7.6 Pl suggest me whether I need any change in medicines etc. I'm taking Januvia-100 also

Dr. Nabajit Talukdar

Cardiology

seems ok basically need control of blood pressure and hypertension get an ecg n echo done

High blood sugar lavel. Gallstone. High blood pressure

Dr. Sanjay Bhatt

Physician

Need to proper investigate and examine. So plz consult doctor nearby.or you can consult me at snergy multiple speciality clinic RD CITY ,BALJEET COMPLEX NEAR SRS MARKET SECTOR 52 gurgaon 9XXXXXX .Advice to maintain calories intake as per weight ,regular walk or aerobic exercises ,on time take your medicines and once a month visit your diabetologist for routine examination and investigations. Will definitely controlled your sugar and u can live healthy life.

High Sugar, high blood pressure

Dr. Sanjay Bhatt

Physician

FAQs

How long does it take for Zione DS O 20mg/12.5mg Tablet to work?

You may notice a decrease in your blood pressure effectively within 2 weeks of starting Zione DS O 20mg/12.5mg Tablet. However, it may take about 8 weeks to see the full benefits of this medicine. Talk to your doctor in case you have any concerns regarding Zione DS O 20mg/12.5mg Tablet, but do not stop taking it without consulting the doctor.

At what time of the day should you take Zione DS O 20mg/12.5mg Tablet?

Your doctor may suggest to take your first dose before bedtime, considering that this medicine can make you feel dizzy. After the very first dose you can take Zione DS O 20mg/12.5mg Tablet at any time of the day. It is important to take this medicine at the same time every day. If not sure, contact your doctor.

Can I feel dizzy after taking Zione DS O 20mg/12.5mg Tablet?

Yes, the use of Zione DS O 20mg/12.5mg Tablet can make you feel dizzy. This may occur when you suddenly get up from a lying or sitting position. To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.

What are the other lifestyle changes I should make while using Zione DS O 20mg/12.5mg Tablet?

Lifestyle changes play a major role in keeping you healthy if you are taking Zione DS O 20mg/12.5mg Tablet. Avoid taking excess salt in your diet and find ways to reduce or manage stress in your life. Practice yoga or meditation or take up a hobby. Ensure that you have a sound sleep every night as this also helps to reduce stress levels and helps to keep your blood pressure normal. Stop smoking and alcohol consumption as this helps in lowering your blood pressure and preventing heart problems. Exercise regularly and take a balanced diet that includes whole grains, fresh fruits, vegetables and fat-free products. Consult your doctor if you need any further guidance to get the maximum benefit of Zione DS O 20mg/12.5mg Tablet and to keep yourself healthy.

Can Zione DS O 20mg/12.5mg Tablet cause weight gain?

No, Zione DS O 20mg/12.5mg Tablet does not cause weight gain. However, in very rare cases, chronic diarrhea with substantial weight loss may occur. If a patient develops diarrhea while taking Zione DS O 20mg/12.5mg Tablet and no other cause of diarrhea can be deduced, the doctor may suggest discontinuation of the medicine and recommend another medicine.

What are the serious side effects of Zione DS O 20mg/12.5mg Tablet?

The serious side effects of Zione DS O 20mg/12.5mg Tablet include skin rash or itchiness, painful joints, fast heart beat, shortness of breath or tightness in the chest. Serious side effects may also include aching, tender or weak muscles not caused by exercise and swelling of the hands, feet or ankles. Zione DS O 20mg/12.5mg Tablet may also cause symptoms that may indicate high potassium levels in the blood, such as nausea, diarrhea, muscle weakness and change in heart rhythm. If you experience any of these symptoms, call your doctor immediately.

Can Zione DS O 20mg/12.5mg Tablet affect my fertility or sex life?

Some blood pressure medicines (including water pills like hydrochlorothiazide) may affect a man’s ability to gain or maintain an erection (erectile dysfunction). However, it is thought that other blood pressure medicines can actually improve erectile dysfunction. If you are worried or notice some changes, talk to your doctor. There is no firm evidence which suggests any effect on the fertility of either men or women with the use of Zione DS O 20mg/12.5mg Tablet.

For how long do I need to take Zione DS O 20mg/12.5mg Tablet? Is it safe to take long term?

You may have to take Zione DS O 20mg/12.5mg Tablet life long. Zione DS O 20mg/12.5mg Tablet controls high blood pressure but does not cure it. Do not stop taking it even if your blood pressure is well controlled. Zione DS O 20mg/12.5mg Tablet is generally considered safe to be taken for a long term. In some cases, long-term use may adversely affect the kidneys and the kidneys may not function as they should. Therefore, your doctor may prescribe regular blood tests to check urea, creatinine and potassium levels to keep a track of your kidneys functions.

Can I take Zione DS O 20mg/12.5mg Tablet before surgery?

Your doctor may advise you to stop taking Zione DS O 20mg/12.5mg Tablet 24 hours before surgery. This is because Zione DS O 20mg/12.5mg Tablet can further reduce your blood pressure when used with anesthetics. So, inform your doctor that you are taking Zione DS O 20mg/12.5mg Tablet if you will be given general anesthetics (medicines that put you to sleep) or are scheduled to have any surgery.

Show less

Related lab tests

Kidney Function Test

Related ayurvedic ingredients

Green Tea

Cocoa

Fish Oil

Top Cardiologists

Dr. Balbir Singh

MBBS, MD, DM, Fellowship, Fellowship

4.8 ★

Dr. Tapan Ghose

MBBS, DNB, MD, DNB, Fellowship, Fellowship

4.5 ★

Dr. Dhananjay Kumar Jhamb

MBBS, MD, DM

4.7 ★

Dr. Manjinder Sandhu

MBBS, MD, DNB, DM, Fellowship, Fellowship

4.7 ★

Dr. R. R. Kasliwal

MBBS, MD, DM, Fellowship

4.7 ★

Want to share the information?

Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

MedIndia. Olmesartan. [Accessed 11 Apr. 2019] (online) Available from:
Chlorthalidone [Prescribing Information]. East Brunswick, NJ: Casper Pharma LLC; 2019. [Accessed 28th Sept. 2023] (online) Available from:
Olmesartan Medoxomil [Package Insert Leaflet]. Kenton, Middlesex: Glenmark Pharmaceuticals Europe Limited; 2022. [Accessed 28th Sept. 2023] (online) Available from:

Marketer details

Name: Unichem Laboratories Ltd

Address: Unichem Laboratories Ltd., Unichem Bhavan, Prabhat Estate, Off S.V.Road, Jogeshwari (West), Mumbai – 400 102

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.