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Zolmist Nasal Spray

Zolmitriptan (5mg)
Genuine
Authenticity Assured
Prescription
required
Zolmist Nasal Spray is used to treat acute migraine attacks. It works by narrowing the blood vessels, thereby relieving migraine headaches and preventing the attack from becoming worse.

Written By Dr. Syeda Aafia, MBA, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 15 May 2026 | 02:38 PM (IST)
₹675 MRP ₹737.398% off 
We do not facilitate sale of this product at present
 
 
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General Information

The content is shown in English
Zolmist Nasal Spray image
Zolmist Nasal Spray image
Zolmist Nasal Spray image
Zolmist Nasal Spray image
Zolmist Nasal Spray image

Product introduction

Zolmist Nasal Spray is taken by mouth with or without food. Never skip any doses and try to finish the full course of treatment even if you feel better. In case you missed a dose, take it as soon as you remember it. You should continue to take this medicine as long as the doctor advises and do not stop taking it suddenly. Consult your doctor if you develop stomach pain, bloody diarrhea, or worsening high blood pressure while taking this medicine. Your doctor may advise for regular eye checkups if you have been taking this medicine for a longer time.


Side effects associated with the use of this medicine include unusual taste, paresthesia, dizziness, and hyperesthesia. These effects vary in severity and should always be reported to your doctor. Your doctor may adjust the dose, delay treatment, or provide supportive care to help manage them safely.


It may cause dizziness, do not drive or operate machinery until you know how this medicine affects you. This medicine may cause an increase in blood pressure, keep a check on your blood pressure while taking this medicine. In case you experience severe chest pain that does not go away or you have wheezing, breathing problems, or any skin rashes, contact the doctor as soon as possible.

Uses of Zolmist Nasal Spray

Benefits of Zolmist Nasal Spray

Acute migraine headache
Zolmist Nasal Spray provides quick relief from migraine attacks by helping reduce headache pain, nausea, and sensitivity to light or sound. It works fast through the nasal route, making it especially helpful when oral medicines are not suitable due to nausea or vomiting. Using it at the early signs of a migraine can help restore daily functioning and improve comfort within a short time.

Side effects of Zolmist Nasal Spray

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Zolmist
  • Taste change
  • Hyperesthesia (increased sensitivity)
  • Warm sensation
  • Paresthesia (tingling or pricking sensation)
  • Dizziness

How to use Zolmist Nasal Spray

Use this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Insert the bottle tip into one nostril and close the other nostril. Direct the spray towards the sides of your nostril, away from the cartilage dividing the two sides of your nose. As you spray, breath gently and keep the head upright. Repeat the same process for the other nostrils.

How Zolmist Nasal Spray works

Migraine headaches are thought to result from the dilatation (swelling) of blood vessels in the head. Zolmist Nasal Spray is rapidly absorbed into the bloodstream through the inner lining of the nose. Once absorbed, it works by constricting (narrowing) the blood vessels in the head, stops transmission of pain signals to the brain, and blocks the release of chemicals that cause nausea and other migraine symptoms. This relieves the migraine attack.

Quick tips

  • You have been prescribed Zolmist Nasal Spray for treatment of migraine headaches.
  • Some tips that may help avoid a migraine attack:
    • Have your meals at the same time everyday
    • Avoid bright lights and extreme temperatures
    • Avoid loud music and noisy places
    • Avoid chocolates, cheese, processed food, alcohol and smoking
    • Get enough sleep and avoid stress
  • It may cause sleepiness. Don't drive or do anything that requires mental focus until you know how it affects you.
  • Notify your doctor if your migraine occurs more often after starting the medication.
  • Notify your doctor if you have stomach pain, headache, bloody diarrhoea or worsening high blood pressure.
  • Inform your doctor if you have a history of heart disease or stroke.
  • This medication does not prevent migraine attacks from happening.
  • You have been prescribed Zolmist Nasal Spray for treatment of migraine headaches.
  • Some tips that may help avoid a migraine attack:
    • Have your meals at the same time everyday
    • Avoid bright lights and extreme temperatures
    • Avoid loud music and noisy places
    • Avoid chocolates, cheese, processed food, alcohol and smoking
    • Get enough sleep and avoid stress
  • It may cause sleepiness. Don't drive or do anything that requires mental focus until you know how it affects you.
  • Notify your doctor if your migraine occurs more often after starting the medication.
  • Notify your doctor if you have stomach pain, headache, bloody diarrhoea or worsening high blood pressure.
  • Inform your doctor if you have a history of heart disease or stroke.
  • This medication does not prevent migraine attacks from happening.

Safety advice

Alcohol

Alcohol

No interaction found/established
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Zolmist Nasal Spray during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Information regarding the use of Zolmist Nasal Spray during breastfeeding is not available. Please consult your doctor.
Driving

Driving

No interaction found/established
Kidney

Kidney

No interaction found/established
Liver

Liver

No interaction found/established

Interaction with drugs

Taking Zolmist with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Life-threatening

Citalopram (Oral Route)

If concurrent use is essential, watch out for symptoms of serotonin syndrome such as tremors, fever, diarrhea or agitation and consult your doctor if you experience them. Your doctor may monitor and adjust the doses as per the observations.
Life-threatening

Duloxetine (Oral Route)

If concurrent use is essential, watch out for symptoms of serotonin syndrome such as tremors, fever, diarrhea or agitation and consult your doctor if you experience them. Your doctor may monitor and adjust the doses as per the observations.
Life-threatening

Escitalopram Oxalate (Oral Route)

If concurrent use is essential, watch out for symptoms of serotonin syndrome such as tremors, fever, diarrhea or agitation and consult your doctor if you experience them. Your doctor may monitor and adjust the doses as per the observations.
Life-threatening

Fluoxetine (Oral Route)

If concurrent use is essential, watch out for symptoms of serotonin syndrome such as tremors, fever, diarrhea or agitation and consult your doctor if you experience them. Your doctor may monitor and adjust the doses as per the observations.
Life-threatening

Fluvoxamine (Oral Route)

If concurrent use is essential, watch out for symptoms of serotonin syndrome such as tremors, fever, diarrhea or agitation and consult your doctor if you experience them. Your doctor may monitor and adjust the doses as per the observations.

Frequently asked questions

If you are having frequent or daily headaches despite (or because of) the regular use of headache medications, it is suggestive of medication overuse headache. You should consult your doctor who may discontinue the medication for sometime.
Taking an overdose of Zolmist Nasal Spray may cause fainting, dizziness, slow heartbeat, change in electrical activity of the heart, vomiting and inability to retain urine or stools.
No, Zolmist Nasal Spray is not used for the prevention of migraine attacks or cluster headaches. It should only be used where a clear diagnosis of migraine has been established.
Before taking Zolmist Nasal Spray, you should tell your doctor if you have heart disease, high blood pressure, diabetes, liver or kidney disease or a family history of heart disease. You should also inform your doctor if you smoke, have had your menopause, or are a man aged 40 years or more. Let your doctor know if your headache is associated with dizziness, difficulty in walking, lack of coordination or weakness in the leg and arm. Your doctor should also know if you are taking medicines to treat depression such as sertraline, escitalopram oxalate, fluoxetine, venlafaxine, or duloxetine. It is also important to inform your doctor if you have had short-lived chest pain and tightness.
Migraine may be triggered by several factors. Some of the common triggers are caffeine withdrawal, changes in hormone levels during menstruation or with the use of birth control pills. Migraine also gets triggered with changes in sleep patterns, such as not getting enough sleep, drinking alcohol, missing meals, or smoking. Rigorous exercise or other physical stress, loud noises or bright lights, odors or perfumes, or exposure to smoke and stress and anxiety may also act as a trigger.
Zolmist Nasal Spray belongs to a family of tryptamine-based drugs called Triptans. You should not take another triptan along with Zolmist Nasal Spray. Taking two triptans together may trigger a heart attack and may also result in an increase in blood pressure.
Migraines may run in families. Migraines occur more often in women than men. It has been noticed that some women, but not all, have fewer migraines when they are pregnant.
Some people develop aura before getting a migraine attack. It may include visual problems, such as seeing flashing lights, zig-zag patterns or blind spots, numbness, dizziness, or a tingling sensation like pins and needles, or feeling off balance. You may also have difficulty speaking and loss of consciousness, although this is unusual.
Medicines for prevention of migraine are usually used if you have tried avoiding possible triggers but are still experiencing migraines. You may also be prescribed these medicines if you experience very severe migraine attacks, or if your attacks happen frequently.
No, Zolmist Nasal Spray does not cause liver damage, but you should let your doctor know if you have any liver problem, before taking Zolmist Nasal Spray.
Once your migraine headache has started, take Zolmist Nasal Spray as soon as possible. Do not use it to prevent an attack. Always take this medicine exactly as your doctor has told you. Check with your doctor or pharmacist if you are not sure.
Yes, Zolmist Nasal Spray can cause an increase in blood pressure. However, it is does not occur in everyone. But, you should keep a check on your blood pressure during therapy with Zolmist Nasal Spray.
If you are having frequent or daily headaches despite (or because of) the regular use of headache medications, it is suggestive of medication overuse headache. You should consult your doctor who may discontinue the medication for sometime.
Taking an overdose of Zolmist Nasal Spray may cause fainting, dizziness, slow heartbeat, change in electrical activity of the heart, vomiting and inability to retain urine or stools.
No, Zolmist Nasal Spray is not used for the prevention of migraine attacks or cluster headaches. It should only be used where a clear diagnosis of migraine has been established.
Before taking Zolmist Nasal Spray, you should tell your doctor if you have heart disease, high blood pressure, diabetes, liver or kidney disease or a family history of heart disease. You should also inform your doctor if you smoke, have had your menopause, or are a man aged 40 years or more. Let your doctor know if your headache is associated with dizziness, difficulty in walking, lack of coordination or weakness in the leg and arm. Your doctor should also know if you are taking medicines to treat depression such as sertraline, escitalopram oxalate, fluoxetine, venlafaxine, or duloxetine. It is also important to inform your doctor if you have had short-lived chest pain and tightness.
Migraine may be triggered by several factors. Some of the common triggers are caffeine withdrawal, changes in hormone levels during menstruation or with the use of birth control pills. Migraine also gets triggered with changes in sleep patterns, such as not getting enough sleep, drinking alcohol, missing meals, or smoking. Rigorous exercise or other physical stress, loud noises or bright lights, odors or perfumes, or exposure to smoke and stress and anxiety may also act as a trigger.
Zolmist Nasal Spray belongs to a family of tryptamine-based drugs called Triptans. You should not take another triptan along with Zolmist Nasal Spray. Taking two triptans together may trigger a heart attack and may also result in an increase in blood pressure.
Migraines may run in families. Migraines occur more often in women than men. It has been noticed that some women, but not all, have fewer migraines when they are pregnant.
Some people develop aura before getting a migraine attack. It may include visual problems, such as seeing flashing lights, zig-zag patterns or blind spots, numbness, dizziness, or a tingling sensation like pins and needles, or feeling off balance. You may also have difficulty speaking and loss of consciousness, although this is unusual.
Medicines for prevention of migraine are usually used if you have tried avoiding possible triggers but are still experiencing migraines. You may also be prescribed these medicines if you experience very severe migraine attacks, or if your attacks happen frequently.
No, Zolmist Nasal Spray does not cause liver damage, but you should let your doctor know if you have any liver problem, before taking Zolmist Nasal Spray.

Fact Box

Chemical Class

Tryptamine derivative

Habit Forming

No

Therapeutic Class

NEURO CNS

Action Class

Triptans (5-HT1B/1D Agonists)
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100% genuine products
Safe & secure payments
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User feedback

Once A Day
100%
Acute migraine headache
93%
Others
7%
Excellent
53%
Average
47%
Throat pain
33%
Sleepiness
33%
No Side Effect
17%
Flushing (sense of warmth in the face, ears, neck and trunk)
17%
With or without food
100%
Expensive
50%
Not Expensive
28%
Average
22%
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Cipla Ltd
Address: Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013

Vendor Details

Country of origin: India
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