





Zolmist Nasal Spray
Written By Dr. Syeda Aafia, MBA, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 15 May 2026 | 02:38 PM (IST)
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General Information






Product introduction
Zolmist Nasal Spray is taken by mouth with or without food. Never skip any doses and try to finish the full course of treatment even if you feel better. In case you missed a dose, take it as soon as you remember it. You should continue to take this medicine as long as the doctor advises and do not stop taking it suddenly. Consult your doctor if you develop stomach pain, bloody diarrhea, or worsening high blood pressure while taking this medicine. Your doctor may advise for regular eye checkups if you have been taking this medicine for a longer time.
Side effects associated with the use of this medicine include unusual taste, paresthesia, dizziness, and hyperesthesia. These effects vary in severity and should always be reported to your doctor. Your doctor may adjust the dose, delay treatment, or provide supportive care to help manage them safely.
It may cause dizziness, do not drive or operate machinery until you know how this medicine affects you. This medicine may cause an increase in blood pressure, keep a check on your blood pressure while taking this medicine. In case you experience severe chest pain that does not go away or you have wheezing, breathing problems, or any skin rashes, contact the doctor as soon as possible.
Uses of Zolmist Nasal Spray
Benefits of Zolmist Nasal Spray
Zolmist Nasal Spray provides quick relief from migraine attacks by helping reduce headache pain, nausea, and sensitivity to light or sound. It works fast through the nasal route, making it especially helpful when oral medicines are not suitable due to nausea or vomiting. Using it at the early signs of a migraine can help restore daily functioning and improve comfort within a short time.
Side effects of Zolmist Nasal Spray
- Taste change
- Hyperesthesia (increased sensitivity)
- Warm sensation
- Paresthesia (tingling or pricking sensation)
- Dizziness
How to use Zolmist Nasal Spray
How Zolmist Nasal Spray works
Quick tips
- You have been prescribed Zolmist Nasal Spray for treatment of migraine headaches.
- Some tips that may help avoid a migraine attack:
- Have your meals at the same time everyday
- Avoid bright lights and extreme temperatures
- Avoid loud music and noisy places
- Avoid chocolates, cheese, processed food, alcohol and smoking
- Get enough sleep and avoid stress
- It may cause sleepiness. Don't drive or do anything that requires mental focus until you know how it affects you.
- Notify your doctor if your migraine occurs more often after starting the medication.
- Notify your doctor if you have stomach pain, headache, bloody diarrhoea or worsening high blood pressure.
- Inform your doctor if you have a history of heart disease or stroke.
- This medication does not prevent migraine attacks from happening.
- You have been prescribed Zolmist Nasal Spray for treatment of migraine headaches.
- Some tips that may help avoid a migraine attack:
- Have your meals at the same time everyday
- Avoid bright lights and extreme temperatures
- Avoid loud music and noisy places
- Avoid chocolates, cheese, processed food, alcohol and smoking
- Get enough sleep and avoid stress
- It may cause sleepiness. Don't drive or do anything that requires mental focus until you know how it affects you.
- Notify your doctor if your migraine occurs more often after starting the medication.
- Notify your doctor if you have stomach pain, headache, bloody diarrhoea or worsening high blood pressure.
- Inform your doctor if you have a history of heart disease or stroke.
- This medication does not prevent migraine attacks from happening.
Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver
Interaction with drugs
Citalopram (Oral Route)
Duloxetine (Oral Route)
Escitalopram Oxalate (Oral Route)
Fluoxetine (Oral Route)
Fluvoxamine (Oral Route)
Frequently asked questions
Fact Box
Chemical Class
Habit Forming
Therapeutic Class
Action Class
References
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1518-19.
- Zolmitriptan [FDA Label]. Wilmington, DE: AstraZeneca UK Limited; 2003 [revised Sep. 2013]. [Accessed 19 Mar. 2019] (online) Available from:
- Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Zolmitriptan. [Updated 2020 Jan 20]. [Accessed 20 Feb. 2020] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 19 Mar. 2019] (online) Available from:
- Zolmitriptan [Prescribing Information]. Wilmington, Delaware: AstraZeneca Pharmaceuticals LP; 2003. [Accessed 28 Mar. 2023] (online) Available from:
- Zolmitriptan [Prescribing Information]. Bridgewater, NJ: Amneal Pharmaceuticals LLC; 2025. [Accessed 8 Jul. 2025] (online) Available from:




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