Zonegran Tablet
Prescription Required
Product introduction
Zonegran Tablet is an anti-epileptic medicine used to treat seizures in epilepsy. It can be used by itself to treat adults or along with other medicines to treat adults and children. It helps to prevent seizures affecting a part or whole of the brain.
Zonegran Tablet suppresses the abnormal electrical activity in the brain. You can take it with or without food but try to take it at the same time each day to get the most benefit. The dose will depend on your condition and how you respond to the medicine. Your doctor will advise the right dose for you.
You should continue taking it for as long as your doctor has told you to, even if you feel well. If you stop or miss doses your seizures could get worse. It may take several months to come off it safely. It is advised not to change the brand of medication without doctor consultation, and always keep a stock of medicine with you.
Very few people taking it have any serious problems but the most common side effects of this medicine include dizziness, loss of appetite, memory loss, drowsiness, and impaired concentration. You may also experience altered walking, impaired coordination, and unusual anger. Side effects are more common during the first few weeks and usually lessen as your body gets used to the medicine. Most do not need medical attention, but some of them can be serious. Let your doctor know if you have any symptoms as there may be ways of preventing or reducing them.
A small number of people being treated with this medicine have had thoughts of harming or killing themselves. Contact your doctor if your mood changes for the worse. Please do not take this medicine if you are allergic to sulfa medicines.
Before taking it, you should tell your doctor if you have kidney problems, depression or suicidal thoughts and if you are pregnant or planning to become pregnant. You should not breastfeed while taking this medicine. Alcohol may increase the risk of seizures and worsen the side effects such as drowsiness and dizziness. Avoid alcohol while taking this medicine. Drowsiness and dizziness may affect your ability to drive or operate machinery. Your kidney function may need to be tested often while taking this medicine.
Zonegran Tablet suppresses the abnormal electrical activity in the brain. You can take it with or without food but try to take it at the same time each day to get the most benefit. The dose will depend on your condition and how you respond to the medicine. Your doctor will advise the right dose for you.
You should continue taking it for as long as your doctor has told you to, even if you feel well. If you stop or miss doses your seizures could get worse. It may take several months to come off it safely. It is advised not to change the brand of medication without doctor consultation, and always keep a stock of medicine with you.
Very few people taking it have any serious problems but the most common side effects of this medicine include dizziness, loss of appetite, memory loss, drowsiness, and impaired concentration. You may also experience altered walking, impaired coordination, and unusual anger. Side effects are more common during the first few weeks and usually lessen as your body gets used to the medicine. Most do not need medical attention, but some of them can be serious. Let your doctor know if you have any symptoms as there may be ways of preventing or reducing them.
A small number of people being treated with this medicine have had thoughts of harming or killing themselves. Contact your doctor if your mood changes for the worse. Please do not take this medicine if you are allergic to sulfa medicines.
Before taking it, you should tell your doctor if you have kidney problems, depression or suicidal thoughts and if you are pregnant or planning to become pregnant. You should not breastfeed while taking this medicine. Alcohol may increase the risk of seizures and worsen the side effects such as drowsiness and dizziness. Avoid alcohol while taking this medicine. Drowsiness and dizziness may affect your ability to drive or operate machinery. Your kidney function may need to be tested often while taking this medicine.
Uses of Zonegran Tablet
Benefits of Zonegran Tablet
In Epilepsy/Seizures
Zonegran Tablet slows down electrical signals in the brain which cause seizures (fits). It can also help reduce symptoms such as confusion, uncontrollable jerking movements, loss of awareness, and fear or anxiety. The medicine can allow you to do some activities that you would otherwise be forbidden or scared to do (such as swimming and driving). It can take a few weeks for this medicine to work (because the dose has to be increased slowly) and during this time you may still have seizures. Do not stop using this medicine even if you feel well, until your doctor advises you to. Missing doses may trigger a seizure.
Side effects of Zonegran Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Zonegran
- Dizziness
- Loss of appetite
- Memory impairment
- Drowsiness
- Impaired concentration
- Altered walking
- Impaired coordination
- Anger
How to use Zonegran Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Zonegran Tablet may be taken with or without food, but it is better to take it at a fixed time.
How Zonegran Tablet works
Zonegran Tablet is an antiepileptic medication. It prevents seizures in patients with epilepsy by suppressing the abnormal and excessive activity of the nerve cells in the brain.
Safety advice
Alcohol
UNSAFE
Zonegran Tablet may cause excessive drowsiness with alcohol.
Pregnancy
CONSULT YOUR DOCTOR
Zonegran Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Zonegran Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Zonegran Tablet may cause side effects which could affect your ability to drive.
As Zonegran Tablet may affect your concentration, ability to react/respond, and may make you feel sleepy, particularly at the beginning of your treatment or after your dose is increased.
As Zonegran Tablet may affect your concentration, ability to react/respond, and may make you feel sleepy, particularly at the beginning of your treatment or after your dose is increased.
Kidney
CAUTION
Zonegran Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Zonegran Tablet may be needed. Please consult your doctor.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Zonegran Tablet in patients with liver disease. Please consult your doctor.
Use of Zonegran Tablet is not recommended in patients with severe liver disease.
Use of Zonegran Tablet is not recommended in patients with severe liver disease.
What if you forget to take Zonegran Tablet?
If you miss a dose of Zonegran Tablet, skip it and continue with your normal schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine
Quick tips
- Take your medication regularly as directed by your doctor as missing doses can trigger seizures.
- Do not change the brand of your medicine and make sure that you have sufficient amount of medicine present with you.
- Some healthy tips to prevent seizures:
- Take a healthy diet along with regular exercise.
- Practice yoga every day.
- Get enough sleep at nighttime.
- Limit the use of screen time such as mobile/ laptop.
- Take your medication on time.
- Do not drive or do anything that requires mental focus until you know how this medicine affects you.
- Drink plenty of water while taking Zonegran Tablet to reduce the risk of kidney stones and heat stroke. Inform your doctor if you have sudden pain in your stomach, pain on urinating, or if you find blood in your urine.
- It may cause loss of appetite and weight. Monitor your weight regularly.
- Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts or behavior.
- Do not stop taking the medication suddenly without talking to your doctor as it may increase the seizure frequency.
- Zonegran Tablet is used along with other medicines to help control your seizures.
- Do not drive or do anything that requires mental focus until you know how this medicine affects you.
- Dress lightly during hot climates or when exercising and check carefully for signs of decreased sweating or heat stroke.
- Drink plenty of water while taking Zonegran Tablet to reduce the risk of kidney stones and heat stroke. Inform your doctor if you have sudden pain in your stomach, pain on urinating, or if you find blood in your urine.
- It may cause loss of appetite and weight. Monitor your weight regularly.
- Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts or behavior.
- Do not stop taking the medication suddenly without talking to your doctor as it may increase the seizure frequency.
- Take your medication regularly as directed by your doctor as missing doses can trigger seizures.
- Do not change the brand of your medicine and make sure that you have sufficient amount of medicine present with you.
- Some healthy tips to prevent seizures:
- Take a healthy diet along with regular exercise.
- Practice yoga every day.
- Get enough sleep at nighttime.
- Limit the use of screen time such as mobile/ laptop.
- Take your medication on time.
Fact Box
Chemical Class
Benzisoxazole & Sulfonamide Derivatives
Habit Forming
No
Therapeutic Class
NEURO CNS
Action Class
Carbonic Anhydrase Inhibitors (CAIs)- Brain
Interaction with drugs
Taking Zonegran with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Fosphenytoin may reduce blood levels of Zonisamide.
Your doctor may monitor the effects of Zonisamide along with your overall treatment and adjust the doses as per the observation
Carbamazepine may reduce blood levels of Zonisamide.
Your doctor may monitor the effects of Zonisamide along with your overall treatment and adjust the doses as per the observatio
Orlistat may reduce efficacy of Zonisamide.
Watch out for symptoms such as tremors. seizures or impaired coordination and consult your doctor if you experience them. Your doctor m
Concurrent use may increase the risk of lactic acid build up in the blood.
If concurrent use is essential, watch out for symptoms such as weakness, nausea, vomiting, abdominal pai
Phenobarbitone may reduce blood levels of Zonisamide.
Your doctor may monitor your treatment and adjust the doses as per the observations.
Patient concerns
User feedback
Patients taking Zonegran Tablet
Twice A Day
80%
Once A Day
20%
What are you using Zonegran Tablet for?
Epilepsy
89%
Others
11%
How much was the improvement?
Average
45%
Excellent
30%
Poor
25%
What were the side-effects while using Zonegran Tablet?
No Side Effec*
20%
Agitation
13%
Sleepiness
13%
Nausea
7%
Dizziness
7%
*No Side Effect
How do you take Zonegran Tablet?
With food
50%
With or witho*
50%
*With or without food
Please rate Zonegran Tablet on price
Expensive
48%
Average
36%
Not Expensive
15%
FAQs
What happens if I stop taking Zonegran Tablet?
Do not stop taking Zonegran Tablet without talking to your doctor. Stopping Zonegran Tablet suddenly may cause serious problems, including seizures that will not stop.
My friend, who was on Zonegran Tablet, developed severe muscle pain with fever. What could this be due to?
Severe muscle pain or weakness, with or without fever, could be due to Zonegran Tablet. Consult your doctor immediately. The doctor may suggest some blood tests to check your levels of serum creatine phosphokinase and aldolase enzymes. Elevated levels of these enzymes may prompt the doctor to discontinue Zonegran Tablet.
What are the effects of Zonegran Tablet in children?
Zonegran Tablet works well in children and is well tolerated by most of them. The common side effects in children include problems with thinking or behavior, followed by stomach upset. One dangerous side effect of Zonegran Tablet in children is decreased sweating with fever. This affects children but not adults and is more common in summers.
I have been taking Zonegran Tablet for epilepsy since a month, but now I feel that my life has come to an end and sometimes I want to harm myself. Is it because of the medicine? What should I do?
Though uncommon, Zonegran Tablet may increase the risk of suicidal thoughts or behavior. Sometimes, it can also be due to the disease itself. You should immediately consult your doctor who will consider discontinuing Zonegran Tablet. We recommend that you take the help of your friend or relative to go to the hospital.
Does Zonegran Tablet cause weight loss?
Yes, Zonegran Tablet may cause weight loss. If you lose weight, consult a dietician for dietary supplement or try to increase your food portions. In case you lose a lot of weight, consider discontinuing Zonegran Tablet after consulting your doctor. Weight loss may be more serious in children, so be cautious and keep monitoring the weight.
Does Zonegran Tablet affect the working of birth control pills?
No, Zonegran Tablet does not interfere with the working of birth control pills.
Does Zonegran Tablet have any effect on kidneys?
Yes, if you are at a risk of developing kidney stones, taking Zonegran Tablet may increase that risk. Stones can lead to further kidney damage. The symptoms of kidney stones include severe sharp pain in lower abdomen or back pain. Increase your fluid intake which can reduce the risk of kidney stones. Consult your doctor if you get any such symptoms.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Stahl SM, editor. Zonisamide. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 755-58.
- McNamara JO. Pharmacotherapy of the Epilepsies. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 602.
- Porters RJ, Meldrum BS. Antiseizure Drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 412.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1520-21.
- Zonisamide [FDA Label]. St. Michael, Barbados: Concordia Pharmaceuticals Inc.2015 [Revised April 2016]. [Accessed 19 Mar. 2019] (online) Available from:
- Zonisamide [Package Leaflet]. Hatfield, UK: Eisai Manufacturing Ltd.; 2018. [Accessed 17 Jun. 2019] (online) Available from:
- Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Zonisamide. [Updated 2020 Jan 20]. [Accessed 20 Feb. 2020] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 19 Mar. 2019] (online) Available from:
- Zonisamide [Product Information]. Ahmedabad, India: Zydus Lifesciences Ltd.; 2022. [Accessed 07 Aug. 2023]. (online) Available from:
Marketer details
Name: Eisai Pharmaceuticals India Pvt Ltd
Address: 1st Floor, B Wing,Marwah Centre, Krishanlal Marwah Marg, Andheri ( East ), Mumbai - 400072, India
Country of origin: China
Expires on or after: August, 2025
A licensed vendor partner from your nearest location will deliver Zonegran Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
Expires on or after: August, 2025
A licensed vendor partner from your nearest location will deliver Zonegran Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
In case of any issues, contact us
Email ID: [email protected]Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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