Zoryl 0.5 Tablet
Prescription Required
Product introduction
Zoryl 0.5 Tablet belongs to a group of medicines called sulfonylureas and is used to treat type 2 diabetes mellitus in adults. It helps control blood sugar levels in people with diabetes thereby preventing serious complications of diabetes such as kidney damage and blindness.
Zoryl 0.5 Tablet may be used alone or along with other medicines. It should be taken just before or with the first meal of the day. Take it regularly at the same time each day to get the maximum benefit. Your doctor will decide what dose is best for you and this may change from time to time according to your blood sugar levels.
Keep taking Zoryl 0.5 Tablet, even if you feel well or your blood sugar levels are controlled. If you stop it without consulting your doctor, your blood sugar levels could rise to put you at risk of diabetes complications such as kidney damage, blindness, nerve problems, and loss of limbs. Remember that it is only part of a treatment program that should also include a healthy diet, regular exercise, and weight reduction as advised by your doctor. Your lifestyle plays a big part in controlling diabetes.
The most common side effects of taking Zoryl 0.5 Tablet include low blood sugar levels (hypoglycemia), nausea, headache, weakness, and dizziness. Make sure you recognize the signs of having low blood sugar levels, such as sweating, dizziness, headache, and shaking, and know how to deal with them. To prevent this, it is important to have regular meals and always carry a fast-acting source of glucose such as sugary food or fruit juice with you. Drinking alcohol can also increase your risk of low blood sugar levels and hence should be avoided. Some people may experience an increase in weight with this medicine.
You should not take Zoryl 0.5 Tablet if you have type 1 diabetes mellitus, diabetic ketoacidosis (high levels of acid in your blood), or if you have severe kidney or liver disease. Before taking this medicine, tell your doctor if you have ever had heart disease, thyroid disease, or some hormonal conditions, as it may not be suitable. Pregnant or breastfeeding women should also consult their doctor before taking it. Your blood sugar levels should be checked regularly and your doctor may also advise blood tests to monitor your blood cell counts and liver function.
Uses of Zoryl Tablet
Side effects of Zoryl Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Zoryl
- Hypoglycemia (low blood glucose level)
- Headache
- Nausea
- Dizziness
- Weakness
How to use Zoryl Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Zoryl 0.5 Tablet is to be taken with food.
How Zoryl Tablet works
Zoryl 0.5 Tablet is an antidiabetic medication. It works by increasing the amount of insulin released by the pancreas in order to lower blood glucose.
Safety advice
Alcohol
UNSAFE
It is unsafe to consume alcohol with Zoryl 0.5 Tablet.
Pregnancy
CONSULT YOUR DOCTOR
Zoryl 0.5 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Zoryl 0.5 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Monitoring of the breastfed infant's blood glucose is advisable during maternal therapy with Zoryl 0.5 Tablet
Monitoring of the breastfed infant's blood glucose is advisable during maternal therapy with Zoryl 0.5 Tablet
Driving
CAUTION
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
Kidney
CAUTION
Zoryl 0.5 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Zoryl 0.5 Tablet may be needed. Please consult your doctor.
Use of Zoryl 0.5 Tablet is not recommended in patients with severe kidney disease. These patients can experience very low blood sugar levels which may become normal after a long time.
Use of Zoryl 0.5 Tablet is not recommended in patients with severe kidney disease. These patients can experience very low blood sugar levels which may become normal after a long time.
Liver
CAUTION
Zoryl 0.5 Tablet should be used with caution in patients with liver disease. Dose adjustment of Zoryl 0.5 Tablet may be needed. Please consult your doctor.
However, the use of Zoryl 0.5 Tablet is not recommended in patients with severe liver disease. These patients can experience very low blood sugar levels which may become normal after a long time.
However, the use of Zoryl 0.5 Tablet is not recommended in patients with severe liver disease. These patients can experience very low blood sugar levels which may become normal after a long time.
What if you forget to take Zoryl Tablet?
If you missed a a dose of Zoryl 0.5 Tablet, skip the missed dose and take your next dose at the usual time.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Zoryl 0.5 Tablet
₹8.07/Tablet
GP 0.5 Tablet
USV Ltd
₹6.65/tablet
18% cheaper
Semi-Amaryl Tablet
Sanofi India Ltd
₹5.76/tablet
29% cheaper
Flexiglim 0.5 Tablet
Torrent Pharmaceuticals Ltd
₹5.92/tablet
27% cheaper
Fitglim 0.5mg Tablet
Arlyn Lifesciences Private Limited
₹4.97/tablet
38% cheaper
Glimith 0.5 Tablet
Johnlee Pharmaceuticals Pvt Ltd
₹3.53/tablet
56% cheaper
Quick tips
- Take Zoryl 0.5 Tablet shortly before or with the first main meal of the day (usually breakfast).
- Exercise regularly, eat a healthy diet and take your other diabetes medicines (if prescribed) alongside.
- Monitor your blood sugar level regularly while you are taking Zoryl 0.5 Tablet.
- Zoryl 0.5 Tablet can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.
- Be careful while driving or operating machinery until you know how Zoryl 0.5 Tablet affects you.
- Always carry some sugary food or fruit juice with you in case you experience hypoglycemic symptoms such as cold sweats, cool pale skin, tremor and anxiety.
- Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms, such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).
Fact Box
Chemical Class
Third-generation Sulfonylurea Derivative
Habit Forming
No
Therapeutic Class
ANTI DIABETIC
Action Class
Sulfonylureas (Insulin Secretagogues)
Interaction with drugs
Taking Zoryl with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Concurrent use may increase the risk of low blood sugar levels. Elderly, malnourished, diabetic individuals and those with kidney and heart dysfunction are at higher risk.
If conc
Amiodarone may raise blood levels of Glimepiride.
If concurrent use is essential, watch out for symptoms such as confusion, headache, nausea, dizziness or faintness and consult yo
Amisulpride may reduce the efficacy of Glimepiride.
If concurrent use is essential, your doctor may monitor your glucose levels frequently and adjust the doses as per the observat
Amisulpride may reduce the efficacy of Glimepiride.
If concurrent use is essential, your doctor may monitor your glucose levels frequently and adjust the doses as per the observat
Amiodarone may raise blood levels of Glimepiride.
If concurrent use is essential, watch out for symptoms such as confusion, headache, nausea, dizziness or faintness and consult yo
Patient concerns
User feedback
Patients taking Zoryl 0.5 Tablet
Twice A Day
100%
What are you using Zoryl Tablet for?
Type 2 diabet*
100%
*Type 2 diabetes mellitus
How much was the improvement?
Average
67%
Poor
33%
What were the side-effects while using Zoryl 0.5 Tablet?
Nausea
50%
Headache
50%
How do you take Zoryl Tablet?
Empty stomach
100%
Please rate Zoryl 0.5 Tablet on price
Expensive
67%
Average
33%
FAQs
What is the dosage of Zoryl 0.5 Tablet?
The recommended starting dose of Zoryl 0.5 Tablet is 1 mg or 2 mg once daily, administered with breakfast. If you are at a higher risk of low blood sugar (e.g., the elderly or patients with renal impairment), you will be given a starting dose of 1 mg once daily. The usual maintenance dose is 1–4 mg once daily. The maximum recommended dose is 8 mg once daily. After reaching a daily dose of 2 mg, the dosage will be increased not more than 2 mg at 1- to 2-week intervals, based on your blood glucose level.
Does Zoryl 0.5 Tablet make you sleepy?
Zoryl 0.5 Tablet itself does not cause sleepiness. However, it may cause hypoglycemia (low blood sugar) when used with other anti-diabetes medicine. Because of this you may feel sleepy or have problems in sleeping.
Is Zoryl 0.5 Tablet safe for kidneys?
Zoryl 0.5 Tablet does not affect kidneys in patients with normal kidney function. However, its use should be avoided in patients with severe kidney disease since Zoryl 0.5 Tablet is principally eliminated by the kidneys.
Does Zoryl 0.5 Tablet cause memory loss?
No, it is not known that Zoryl 0.5 Tablet causes memory loss. However, the use of Zoryl 0.5 Tablet may cause low blood sugar which may cause problems with concentration and reduced alertness.
Who should not take Zoryl 0.5 Tablet?
Zoryl 0.5 Tablet should be avoided by patients who are allergic to it, have severe kidney or liver disease, have G6PD-deficiency (an inherited condition affecting red blood cells) or are due to have surgery. Additionally, patients who are trying to get pregnant, are pregnant or breastfeeding, or have insulin-dependent diabetes (type 1 diabetes mellitus) should avoid taking Zoryl 0.5 Tablet.
How long does it take for Zoryl 0.5 Tablet to start working?
Zoryl 0.5 Tablet takes about 2 to 3 hours to reduce blood sugar levels. You may not feel any difference, but this does not mean the medicine is not working. Continue taking the medication as directed by your doctor and if you have any concerns, discuss it with your doctor.
How long do I need to take Zoryl 0.5 Tablet? Can I stop the medication?
Usually, the treatment for diabetes is suggested for a long term. You may have to continue the treatment life long. Zoryl 0.5 Tablet only controls the sugar levels but does not cure it. Do not stop taking Zoryl 0.5 Tablet without talking to your doctor. If you stop taking Zoryl 0.5 Tablet suddenly your diabetes may get worse.
What can happen if I take more than the recommended dose of Zoryl 0.5 Tablet?
Zoryl 0.5 Tablet should be taken strictly as advised by the doctor. Overdose of Zoryl 0.5 Tablet may significantly decrease your blood sugar levels (hypoglycemia). If you think you have taken an excess dose and experience a dip in your sugar level, consume enough sugar (e.g., a small bar of sugar cubes, sweet juice or sweetened tea) and inform a doctor immediately. Severe cases of hypoglycemia accompanied by loss of consciousness and coma require immediate medical treatment and admission into hospital.
Can you take Zoryl 0.5 Tablet on an empty stomach?
No. Taking Zoryl 0.5 Tablet on an empty stomach can cause your blood sugar levels to become too low. Low blood sugar can cause dizziness, shaking, anxiety, irritability, a fast heartbeat, and confusion. Therefore, you should always take the medicine with breakfast or the first meal of the day. If you are skipping your meal, then you should also avoid taking Zoryl 0.5 Tablet.
Can Zoryl 0.5 Tablet cause weight gain?
Yes, Zoryl 0.5 Tablet can cause weight gain. Zoryl 0.5 Tablet is a sulfonylurea drug and causes the pancreas to release insulin. It may stimulate hunger and cause mild weight gain in some people. Patients are advised to eat a healthy balanced diet and exercise regularly to keep their weight stable.
Can Zoryl 0.5 Tablet cause dizziness?
Yes, Zoryl 0.5 Tablet can cause dizziness as a side effect. If this happens to you, sit or lie down until the symptoms pass. Always carry some sugary food or fruit juice with you in case you experience dizziness while travelling.
What should you not eat while taking Zoryl 0.5 Tablet?
It is advisable to avoid foods that are high in saturated and trans fats, instead consume fats from fish and nuts. Control your carbohydrate intake as this directly affects your blood sugar.
Is Zoryl 0.5 Tablet safe to use?
Yes, Zoryl 0.5 Tablet tablet is safe when used as directed by the doctor. However, it may show some side effects. For best results, it should be used in the correct dose and at the same time each day.
Can people with diabetes have proteins?
Yes, people with diabetes must include proteins along with other essential nutrients in their daily diet. Proteins are one of the major energy providers among all essential nutrients. Besides, being the building blocks of the human body, proteins break down into glucose to release energy. Unlike carbohydrates, the metabolism of proteins into glucose is much slower. Therefore, the release of energy usually takes a few hours after consumption. Thus, the spike in blood sugar levels might occur after a few hours when you are on a high-protein diet.
Are artificial sweeteners good for people with diabetes?
No, artificial sweeteners are not good for people with diabetes. They are composed of chemicals that can cause mild to severe side effects. Thus, it is better to limit or avoid their use as much as you can.
Can diabetes cause kidney failure?
Yes, uncontrolled diabetes can cause kidney failure. In the long run, diabetes can affect the kidneys leading to a condition called diabetic nephropathy. Diabetic nephropathy is a condition that is a major cause of kidney failure in patients with diabetes. The best way to prevent damage to kidneys is by keeping diabetes in check, making dietary changes, monitoring sugar levels regularly, getting routine blood tests done, and taking prescribed medications on time.
Can diabetes be cured?
Diabetes is a condition that causes changes in your blood glucose levels, which if left uncontrolled, can lead to serious health complications affecting the heart, brain, kidneys, and eyes. However, with simple lifestyle changes, diet, and medications, one can manage their condition and lead a healthy life.
Want to share the information?
Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Powers AC, D’Alessio D. Endocrine Pancreas and Pharmacotherapy of Diabetes Mellitus and Hypoglycemia. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1255-1257.
- Nolte MS. Pancreatic hormones and antidiabetic drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 740.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 629-30.
- Glimepiride. Bridgewater, New Jersey: Sanofi-Aventis U.S. LLC.; 2009. [Accessed 13 Mar. 2019] (online) Available from:
- DailyMed. Glimepiride [Drug Label Information]. [Accessed 20 Sept. 2021] (online) Available from:
- National Health Services. How and when to take glimepiride. [Last reviewed: 14 Mar. 2022]. [Accessed 28 June 2023]. (online) Available from:
Marketer details
Name: Intas Pharmaceuticals Ltd
Address: Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Country of origin: India
Expires on or after: September, 2025
A licensed vendor partner from your nearest location will deliver Zoryl 0.5 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
Expires on or after: September, 2025
A licensed vendor partner from your nearest location will deliver Zoryl 0.5 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
In case of any issues, contact us
Email ID: [email protected]Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
Lab tests offered by us
Related/Popular tests
189 people bought this recently₹102.85₹121Get 15% OFF
₹93.17+ free shipping with
Inclusive of all taxes
This offer price is valid on orders above ₹1800. Apply coupon HEALTHALL on the cart. Max. coupon discount is ₹380. T&C apply.
1 Strip
15.0 tablets in 1 strip
Variants (2)
Cash on delivery available
Get it delivered in 60 mins
Delivering to:
122019, Gurgaon
Additional offers
Airtel Payments Bank: Pay with Airtel Payments Bank and get 10% cashback up to Rs. 200 cashback on a minimum transaction of ₹1000. Valid only for first-time users for Airtel Payments Bank Savings Bank accounts.
Show more 