Zoryl MS 50mg/1mg/1000mg Tablet IR is a combination of three medicines used to lower blood glucose levels in people with type 2 diabetes mellitus. It is generally prescribed when diet, exercise, and other treatments do not result in adequate glycemic control.

Zoryl MS 50mg/1mg/1000mg Tablet IR is best taken with food; however, take this medicine regularly and at the same time each day to get maximum benefits. The dose and duration are decided according to your condition and how well you respond to it. The doctor may also monitor your blood sugar levels regularly when you are taking this combination medicine.

Keep taking this medicine even if you feel well or your blood sugar levels are controlled. If stopped abruptly, your blood sugar levels could rise and put you at risk of complications. This medication is only part of a treatment program that should also include a healthy diet, regular exercise, and weight reduction because lifestyle habits play a big part in controlling diabetes.

The most common side effects of Zoryl MS 50mg/1mg/1000mg Tablet IR include nausea, vomiting, gastrointestinal disturbances, and hypoglycemia. Let your doctor know if any of these side effects do not go away or get worse. They may be able to help by adjusting the dosage or by prescribing an alternate medicine.

You should not take Zoryl MS 50mg/1mg/1000mg Tablet IR if you have type 1 diabetes mellitus or acute or chronic metabolic acidosis, including diabetic ketoacidosis. Patients with active bladder cancer or a history of bladder cancer should also not take this medicine. Inform your doctor about all the other medicines that you take as some of them can affect or be affected by this medication. Pregnant or breastfeeding women should also consult their doctors before taking it.

Uses of Zoryl MS Tablet IR

Treatment of Type 2 diabetes mellitus

Benefits of Zoryl MS Tablet IR

In Treatment of Type 2 diabetes mellitus

Lowering blood glucose levels is an essential part of managing diabetes as this helps to reduce the risk of serious diabetes-associated complications, such as kidney damage, eye damage, nerve problems, and loss of limbs. Zoryl MS 50mg/1mg/1000mg Tablet IR helps control high blood glucose (sugar) levels. It also reduces the risk of heart diseases like heart attack or stroke. Taking this medicine regularly along with proper diet and exercise will help you live a normal, healthy life.

Side effects of Zoryl MS Tablet IR

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Zoryl MS

Nausea
Vomiting
Gastrointestinal disturbance
Hypoglycemia (low blood glucose level)

How to use Zoryl MS Tablet IR

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Zoryl MS 50mg/1mg/1000mg Tablet IR is to be taken with food.

How Zoryl MS Tablet IR works

Zoryl MS 50mg/1mg/1000mg Tablet IR is a combination of three antidiabetic medications. Sitagliptin helps to control blood sugar levels by increasing substances (incretins) in the body that make the pancreas release more insulin. It also signals the liver to stop producing sugar (glucose) when there is too much sugar in the blood. Glimepiride lowers blood sugar by causing the pancreas to produce insulin (a natural substance that is needed to break down sugar in the body) and helping the body use insulin efficiently. Metformin decreases the amount of glucose you absorb from your food and the glucose made by the liver. It also increases the body's response to insulin, a natural substance that controls the amount of glucose in the blood (blood sugar levels).

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Zoryl MS 50mg/1mg/1000mg Tablet IR.

Pregnancy

CONSULT YOUR DOCTOR

Zoryl MS 50mg/1mg/1000mg Tablet IR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Zoryl MS 50mg/1mg/1000mg Tablet IR is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

CAUTION

Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.

Kidney

CAUTION

Zoryl MS 50mg/1mg/1000mg Tablet IR should be used with caution in patients with severe kidney disease. Dose adjustment of Zoryl MS 50mg/1mg/1000mg Tablet IR may be needed. Please consult your doctor.

Liver

CAUTION

Zoryl MS 50mg/1mg/1000mg Tablet IR should be used with caution in patients with severe liver disease. Dose adjustment of Zoryl MS 50mg/1mg/1000mg Tablet IR may be needed. Please consult your doctor.

What if you forget to take Zoryl MS Tablet IR?

If you miss a dose of Zoryl MS 50mg/1mg/1000mg Tablet IR, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Zoryl MS 50mg/1mg/1000mg Tablet IR

₹12.9/Tablet IR

Istamet G 50mg/1mg/1000mg Tablet IR

Sun Pharma Laboratories Ltd

₹14.25/tablet ir

10% costlier

Azulix SM 50mg/1mg/1000mg Tablet IR

Torrent Pharmaceuticals Ltd

₹12.5/tablet ir

3% cheaper

Sitaxa GM 50mg/1mg/1000mg Tablet IR

Torrent Pharmaceuticals Ltd

₹13.9/tablet ir

8% costlier

Quick tips

Prefer taking Zoryl MS 50mg/1mg/1000mg Tablet IR after a meal or with a snack, as this will reduce the chance of an upset stomach.
Zoryl MS 50mg/1mg/1000mg Tablet IR may cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal. Always carry some sugary food or fruit juice with you in case you experience hypoglycemia (low blood sugar) symptoms, such as fatigue, dizziness, cold sweats, tremor, and anxiety.
If you get unusually thirsty, pass urine more frequently, and feel tired, let your doctor know. These are signs that there is too much sugar in your blood and your dose may need adjusting.
Monitor your blood sugar regularly while taking this medicine.
Lifestyle changes like low sugar diet, exercising, losing weight, not smoking, and cutting down on alcohol intake may help this medication work better.

Fact Box

Habit Forming

Therapeutic Class

ANTI DIABETIC

Patient concerns

Diabetic type 2, using tablet zoryl M1, diabetes in control. Now I am having pain in shoulder intermittently. unable to raise left arm

Dr. Deepak Kumar Soni

Ayurveda

http://www.1mgayush.com/BonesandJoints/products/Arthrella-Oil/Standardmassage with this oil

Diabetes mellitus type 2 ,thirst

Dr. Sanjay Bhatt

Physician

A person can control his or her sugar levels by doing regular exercise and walk or regular aerobic exercises at least 30 to 45 minutes per day.MEDICAL NUTRITIONAL THERAPY THAT IS TO MAINTAIN CALORIES INTAKE AS PER BMI .TAKE HELP OF DIABETIC EDUCATOR. VISIT YOUR DOCTOR AND FOLLOW ALL WHAT DOCTOR SUGGESTED.IN TIME ALL ROUTINE INVESTIGATIONS SHOULD BE DONE.you should not treat it as disease but a start of a healthy life.Uncontrolled sugar levels for long time leads to lower limb weakness which is neuropathy and which is followed by foot ulcers and other complications like kidney or heart problems .online prescription is not allowed without seeing pt.so contact doctor nearby for any change or dose adjustment or visit my clinic at gurgaon sector 52 RdCity snergy multi speciality clinic near SRS MARKET

Diabetes since 2010, taking these medicines (zoryl, vobit,vonderd met)

Dr. Sanjay Bhatt

Physician

A person can control his or her sugar levels by regular exercise and walk or regular aerobic exercises at least 30 to 45 minutes per day.MEDICAL NUTRITIONAL THERAPY THAT IS TO MAINTAIN CALORIES INTAKE AS PER BMI .TAKE HELP OF DIABETIC EDUCATOR. VISIT YOU DOCTOR AND LOW ALL WHAT DOCTOR SUGGESTED.IN TIME ALL ROUTINE INVESTIGATIONS SHOULD BE DONE.you souls not treat it as disease but start of a healthy life.Uncontrolled sugar levels for long time leads to lower limb weakness which is neuropathy and which is followed by foot ulcers and other complications.online prescription is not allowed without seeing pt.so contact doctor nearby for any change or dose adjustment or visit my clinic at gurgaon sector 52 RdCity snergy multi speciality clinic near SRS MARKET

Myself PATIENT choudhart having diabetes from last 01 year. Presently taking ziten and zoryl m1 in morning and zoryl m1 in night. Still having sugar level 238/176. Kindly advise.

Dr. Sanjay Bhatt

Physician

A person can control his or her sugar levels by regular exercise and walk or regular aerobic exercises at least 30 to 45 minutes per day.MEDICAL NUTRITIONAL THERAPY THAT IS TO MAINTAIN CALORIES INTAKE AS PER BMI .TAKE HELP OF DIABETIC EDUCATOR. VISIT YOU DOCTOR AND FOLLOW ALL WHAT DOCTOR SUGGESTED.IN TIME ALL ROUTINE INVESTIGATIONS SHOULD BE DONE.you should not treat it as disease but start of a healthy life.Uncontrolled sugar levels for long time leads to lower limb weakness which is neuropathy and which is followed by foot ulcers and other complications.online prescription is not allowed without seeing pt.so contact doctor nearby for any change or dose adjustment or visit my clinic at gurgaon sector 52 RdCity snergy multi speciality clinic near SRS MARKET

Related lab tests

Glucose - Fasting Blood

Glucose - Postprandial Blood

Glycosylated Hemoglobin

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References

Sitagliptin/metformin HC [Prescribing Information]. Whitehouse Station: Merck & Co., Inc.; 2012. [Accessed 02 Nov. 2023] (online) Available from:
A Multicenter, Randomized, Comparative, Active-Controlled, Double-Blind, Double-Dummy, Phase 3 Study to Assess Efficacy and Safety of Fixed Dose Combination of Sitagliptin Phosphate, Metformin Hydrochloride and Glimepiride Tablets in Comparison to Co- administration of Metformin Hydrochloride and Glimepiride Tablets in Patients with Type 2 Diabetes Mellitus. Protocol No. ICR/21/004, clinical study report dated 3rd July 2023, Sun Pharma Laboratories Limited, Data on file.

Marketer details

Name: Intas Pharmaceuticals Ltd

Address: Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.

Country of origin: India

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