Zotide One Injection
Prescription Required
Product introduction
Zotide One Injection is a man-made version of parathyroid hormone used to treat men and postmenopausal women who have severe osteoporosis with a high risk of fractures. It works by stimulating new bone formation, which improves bone density and decreases the risk of spinal fractures.
Zotide One Injection should be injected under the skin or given by a healthcare professional. You should use it regularly and at the same time each day to get the maximum benefit from it. Usually, it is recommended to take it for a maximum period of 2 years. However, follow the doctor’s advice and complete the course even if you feel better. It should be stored in the refrigerator at a temperature of 2°C to 8°C.
Some common side effects of this medicine include joint pain, injection site reactions (such as pain, swelling, and redness) and leg cramps. consult with your doctor if any of these bother you or do not go away.
Before taking this medicine, let your doctor know if you have kidney stones or any other kidney problems, as it can cause an increase in the amount of calcium in blood or urine. Pregnant and breastfeeding mothers should also consult with their doctors before taking this medicine. Your doctor may advise a bone scan to monitor the progress of your treatment.
Uses of Zotide One Injection
Benefits of Zotide One Injection
In Osteoporosis
Osteoporosis is a common condition that weakens bones, making them fragile and more likely to break. Zotide One Injection helps treat osteoporosis in men as well as in women after menopause. It slows down the rate at which bone is broken down in your body. This maintains bone density and reduces your risk of breaking a bone. The injection is given by a doctor or nurse and should not be self-administered. You can help improve the strength of your bones by doing regular exercise (especially weight-bearing exercise), eating healthy foods containing calcium and Vitamin D and reducing your consumption of alcohol and tobacco. Supplements of calcium and Vitamin D3 are also effective.
Side effects of Zotide One Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Zotide One
- Joint pain
- Injection site reactions (pain, swelling, redness)
- Nausea
- Leg cramps
How to use Zotide One Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Zotide One Injection works
Zotide One Injection is a synthetic form of a natural human hormone called parathyroid hormone (PTH). It works by increasing the number and activity of bone-forming cells (osteoblasts). This strengthens the bones and minimizes the risk of fractures.
Safety advice
Alcohol
CAUTION
Caution is advised when consuming alcohol with Zotide One Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Zotide One Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Zotide One Injection during breastfeeding is not available. Please consult your doctor.
Driving
UNSAFE
Zotide One Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CAUTION
Zotide One Injection should be used with caution in patients with kidney disease. Dose adjustment of Zotide One Injection may be needed. Please consult your doctor.
Use of Zotide One Injection is not recommended in patients with severe kidney disease.
Use of Zotide One Injection is not recommended in patients with severe kidney disease.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Zotide One Injection in patients with liver disease. Please consult your doctor.
What if you forget to take Zotide One Injection?
If you miss a dose of Zotide One Injection, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Zotide One Injection
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Quick tips
- Zotide One Injection should be injected every day under the skin (subcutaneous injection) of the thigh or abdomen.
- Do not take it for more than 2 years.
- You may have low blood pressure and dizziness during the initial few days.
- If you feel dizzy (light-headed) after injection, sit or lie down until you feel better.
- Tell your doctor immediately if you experience nausea, vomiting, constipation, low energy, or muscle weakness. These may be signs of high calcium levels in your blood.
- Tell your doctor if you are breastfeeding, pregnant or plan to become pregnant.
Fact Box
Chemical Class
Parathyroid Hormone Analogs
Habit Forming
No
Therapeutic Class
HORMONES
Action Class
Bone formation stimulator -PTH analogue
Patient concerns
FAQs
Q. Is Zotide One Injection a steroid?
No, Zotide One Injection is not a steroid. However, this medicine may be used to treat osteoporosis caused by long-term use of steroids. Generally, this medicine is used to treat osteoporosis in women of postmenopausal age group and in men who have increased risk of fracture.
Q. Can I take this medication in long term for osteoporosis?
Zotide One Injection should not be taken for longer than 2-year course. It is important to inform the doctor if you have taken this medication in the past, as you should not receive more than one treatment of 24 months course more than once in your lifetime.
Q. How is Zotide One Injection stored at home?
Always keep this medicine stored in a refrigerator at a temperature of about 2°C to 8°C. Be cautious, the temperature should not decrease further as freezing may cause the medicine to get damaged and can lead to loss of activity. Therefore, avoid placing the Zotide One Injection pens close to the ice compartment of the refrigerator. If properly stored this medication can be used up to 28 days after the first injection. If the pen is not empty within 28 days please discard it safely.
Q. Who should not use Zotide One Injection?
The doctor will decide whether the medicine is required for a patient or not. There are few conditions in which the use of Zotide One Injection should be avoided such as in patients with kidney impairment, Paget’s disease, any type of bone cancers or unexplained high levels of serum calcium. It should also be avoided by children, young adult or growing age, pregnant or lactating females. Hence, before starting the medication inform the doctor about any medical condition and the medication you are taking. This will help the doctor to design a proper therapy for you.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Bikle DD. Agents That Affects Bone Mineral Homoestasis. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 766.
- Friedman PA. Agents Affecting Mineral Ion Homeostasis and Bone Turnover. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1300
- Teriparatide. Indianapolis, Indiana: Lilly France; 2008. [Accessed 02 Apr. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 02 Apr. 2019] (online) Available from:
- Teriparatide injection [Prescribing Inforamtion]. Indianapolis, IN: : Lilly USA, LLC; 2021. [Accessed 20 Feb. 2024] (online) Available from:
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Address: Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013
Country of origin: India
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