Zotral 50 Tablet
Prescription Required
Product introduction
Zotral 50 Tablet is a type of antidepressant belonging to the selective serotonin reuptake inhibitor (SSRI) group of medicines. It is prescribed for depression, anxiety-related conditions like obsessive-compulsive disorder, and panic disorder.
Zotral 50 Tablet may also be used to treat premenstrual dysphoric disorder (depression and irritability before menstrual period in women). It can be taken with or without food. The dose and how often you need it will be decided by your doctor so that you get the right amount to control your symptoms.
Your doctor may start you on a lower dose and increase it gradually. Do not change the dose or stop taking it without talking to your doctor, even if you feel well. Doing so may make your condition worse or you may suffer from unpleasant withdrawal symptoms (anxiety, restlessness, palpitations, dizziness, sleep disturbances, etc).
To get the most benefit, take this medicine regularly at the same time each day. Your doctor may advise you to take it in the morning if you have trouble sleeping. It may take a few weeks before you start feeling better. Let your doctor know if you do not see any improvement even after 4 weeks.
Some common side effects of Zotral 50 Tablet include nausea, indigestion, loss of appetite, increased sweating, tremors, insomnia (difficulty in sleeping), and diarrhea. Sexual side effects like decreased sexual drive, delayed ejaculation, and erectile dysfunction may also be seen. Let your doctor know straight away if you develop any sudden worsening of mood or any thoughts about harming yourself.
Before taking this medicine, you should tell your doctor if you have epilepsy (seizure disorder or fits), diabetes, liver or kidney disease, heart problems, or glaucoma. These may affect your treatment. Pregnant or breastfeeding women should also consult their doctor before taking it. Some other medicines may affect the way it works, especially other antidepressants and medicines called MAO inhibitors. Please tell your doctor about all the medicines you are taking to make sure you are safe.
Zotral 50 Tablet may also be used to treat premenstrual dysphoric disorder (depression and irritability before menstrual period in women). It can be taken with or without food. The dose and how often you need it will be decided by your doctor so that you get the right amount to control your symptoms.
Your doctor may start you on a lower dose and increase it gradually. Do not change the dose or stop taking it without talking to your doctor, even if you feel well. Doing so may make your condition worse or you may suffer from unpleasant withdrawal symptoms (anxiety, restlessness, palpitations, dizziness, sleep disturbances, etc).
To get the most benefit, take this medicine regularly at the same time each day. Your doctor may advise you to take it in the morning if you have trouble sleeping. It may take a few weeks before you start feeling better. Let your doctor know if you do not see any improvement even after 4 weeks.
Some common side effects of Zotral 50 Tablet include nausea, indigestion, loss of appetite, increased sweating, tremors, insomnia (difficulty in sleeping), and diarrhea. Sexual side effects like decreased sexual drive, delayed ejaculation, and erectile dysfunction may also be seen. Let your doctor know straight away if you develop any sudden worsening of mood or any thoughts about harming yourself.
Before taking this medicine, you should tell your doctor if you have epilepsy (seizure disorder or fits), diabetes, liver or kidney disease, heart problems, or glaucoma. These may affect your treatment. Pregnant or breastfeeding women should also consult their doctor before taking it. Some other medicines may affect the way it works, especially other antidepressants and medicines called MAO inhibitors. Please tell your doctor about all the medicines you are taking to make sure you are safe.
Uses of Zotral Tablet
- Depression
- Anxiety disorder
- Obsessive-compulsive disorder
- Phobia
- Post traumatic stress disorder
- Treatment of Panic disorder
- Treatment of Premenstrual dysphoric disorder
- Treatment of Anxiety
- Treatment of Premenstrual syndrome (PMS)
Benefits of Zotral Tablet
In Treatment of Panic disorder
Zotral 50 Tablet can help relieve symptoms of many panic disorders including panic attacks. It can help you feel calmer and improve your ability to deal with problems. Do not stop taking it, even when you feel better, unless your doctor advises you to.
In Treatment of Premenstrual dysphoric disorder
Premenstrual dysphoric disorder (PMDD) is a condition in which a woman has severe depression symptoms, irritability, anger and tension before her periods (menstruation). Zotral 50 Tablet helps you feel calm and improves your mood. It works by increasing the amounts of a natural substance in the brain (serotonin) that helps maintain mental balance. Indulging in some relaxation therapy, meditation and yoga might also provide you relief.
In Treatment of Anxiety
Zotral 50 Tablet helps relieve symptoms of many anxiety disorders by increasing the level of a chemical called serotonin in your brain. It has fewer side effects than older antidepressants and is normally taken once a day. It helps you feel calm with a better ability to deal with problems. Exercise and a healthy diet can also improve your mood. Keep taking the medicine until your doctor advises you to stop.
In Treatment of Premenstrual syndrome (PMS)
Zotral 50 Tablet may help reduce PMS symptoms such as mood swings, anxiousness, tiredness, bloating, breast tenderness and headaches. Lifestyle changes such as regular exercise, a healthy diet, getting plenty of sleep, and using relaxation techniques may also be helpful.
Side effects of Zotral Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Zotral
- Delayed ejaculation
- Erectile dysfunction
- Indigestion
- Insomnia (difficulty in sleeping)
- Low sexual desire
- Nausea
- Tremors
- Diarrhea
- Increased sweating
- Loss of appetite
- Sleepiness
- Taste change
How to use Zotral Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Zotral 50 Tablet may be taken with or without food, but it is better to take it at a fixed time.
How Zotral Tablet works
Zotral 50 Tablet is a selective serotonin reuptake inhibitor (SSRI) antidepressant. It works by increasing the levels of serotonin, a chemical messenger in the brain. This improves mood and physical symptoms of depression and also relieves symptoms of obsessive-compulsive disorder, panic disorder, premenstrual dysphoric disorder, and anxiety.
Safety advice
Alcohol
UNSAFE
Zotral 50 Tablet may cause excessive drowsiness with alcohol.
Pregnancy
CONSULT YOUR DOCTOR
Zotral 50 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Zotral 50 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Zotral 50 Tablet may cause side effects which could affect your ability to drive.
Kidney
SAFE IF PRESCRIBED
Zotral 50 Tablet is safe to use in patients with kidney disease. No dose adjustment of Zotral 50 Tablet is recommended.
However, inform your doctor if you have an underlying kidney disease as you may be given a smaller dose initially and then increased slowly as required.
However, inform your doctor if you have an underlying kidney disease as you may be given a smaller dose initially and then increased slowly as required.
Liver
CAUTION
Zotral 50 Tablet should be used with caution in patients with liver disease. Dose adjustment of Zotral 50 Tablet may be needed. Please consult your doctor.
Use of Zotral 50 Tablet is not recommended in patients with severe liver disease.
Use of Zotral 50 Tablet is not recommended in patients with severe liver disease.
What if you forget to take Zotral Tablet?
If you miss a dose of Zotral 50 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
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Quick tips
- Do not drive or do anything requiring concentration until you know how Zotral 50 Tablet affects you.
- Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.
- The addiction/dependence potential of Zotral 50 Tablet is very less.
- Inform your doctor if you experience decreased sex drive or difficulty having an orgasm.
- Do not stop taking the medication suddenly without talking to your doctor.
- It can take 2-3 weeks for Zotral 50 Tablet to start working.
- Do not stop treatment suddenly as this may cause upset stomach, flu-like withdrawal symptoms and sleep disturbance.
- If your doctor asks you to stop Zotral 50 Tablet, you should reduce the dose slowly over 4 weeks.
- Avoid consuming alcohol when taking Zotral 50 Tablet, as it may cause excessive drowsiness and calmness.
- The addiction/dependence potential of Zotral 50 Tablet is very less.
Fact Box
Chemical Class
Tametraline Derivative
Habit Forming
No
Therapeutic Class
NEURO CNS
Action Class
Selective Seretonin Reuptake Inhibitors (SSRIs)
Interaction with drugs
Taking Zotral with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Concomitant use may cause an increase in blood serotonin levels. Patients may experience agitation, increased body temperature, fast heartbeat, muscle rigidity, and loss of coordin
Concurrent use may cause serotonin syndrome.
If concurrent use is essential, watch out for symptoms of serotonin syndrome such as tremors, fever, diarrhea or agitation and consult
Concomitant use may affect heart rhythm and can be fatal.
Do not consume Moclobemide with Sertraline. If Moclobemide is essential, ensure a gap of at least 1 week after discontinu
Concurrent use may cause fatal rise in blood serotonin levels.
Avoid concurrent use unless your doctor considers it safe.
Concomitant use may cause a fatal increase in blood serotonin levels. Patients may experience agitation, increased body temperature, fast heartbeat, muscle rigidity, and loss of co
Patient concerns
User feedback
Patients taking Zotral 50 Tablet
Once A Day
76%
Twice A Day
23%
Thrice A Day
2%
What are you using Zotral Tablet for?
Depression
52%
Anxiety disor*
32%
Others
8%
Obsessive-com*
4%
Post traumati*
4%
*Anxiety disorder, Obsessive-compulsive disorder, Post traumatic stress disorder
How much was the improvement?
Excellent
48%
Average
44%
Poor
7%
What were the side-effects while using Zotral 50 Tablet?
Headache
33%
Delayed ejacu*
33%
Insomnia (dif*
33%
*Delayed ejaculation, Insomnia (difficulty in sleeping)
How do you take Zotral Tablet?
With food
80%
With or witho*
20%
*With or without food
Please rate Zotral 50 Tablet on price
Expensive
44%
Average
33%
Not Expensive
22%
FAQs
How long does it take for Zotral 50 Tablet to work?
You may start noticing an improvement in symptoms within 7 days of taking Zotral 50 Tablet. However, it may take longer to show full response and will vary from person to person.
How long do I need to take Zotral 50 Tablet?
You should continue taking Zotral 50 Tablet as long as your doctor recommends to take it which may be for several months. Doctors usually recommend the medicine for 6 months to a year after you no longer feel depressed. It is important to know that stopping the medication before the suggested time may cause depression to come back.
When is the best time to take Zotral 50 Tablet?
Zotral 50 Tablet is usually taken once a day and can be taken at any time of the day. It can be taken with or without food. Take it as per your convenience but preferably at the same time each day. Some people who have sleep difficulty after taking Zotral 50 Tablet, they should take it in the morning. Whereas, some take it at night to limit the side effects of nausea and vomiting.
Does Zotral 50 Tablet cause sleepiness?
Yes, Zotral 50 Tablet may commonly cause sleepiness. In case you feel dizzy, sleepy or tired after taking Zotral 50 Tablet, you should avoid driving or using heavy machinery. This generally happens within the first few days and weeks after starting Zotral 50 Tablet, which may disappear after 2-3 months of use of Zotral 50 Tablet.
What does Zotral 50 Tablet do for anxiety?
Zotral 50 Tablet belongs to selective serotonin reuptake inhibitor (SSRI) class of medicines. It increases the levels of serotonin which is an important chemical and a neurotransmitter. This increase in serotonin levels can help to improve and regulate your mood, resulting in an improvement in the symptoms of anxiety.
Can I stop taking Zotral 50 Tablet if I am better now?
No, you should not stop taking Zotral 50 Tablet without consulting your doctor. This is because sudden discontinuation of Zotral 50 Tablet may cause withdrawal symptoms. Hence, it is important to gradually reduce the dose with time (over several weeks or months).
What are the withdrawal symptoms of Zotral 50 Tablet?
The withdrawal symptoms of Zotral 50 Tablet include dizziness, nausea, numbness or tingling in the hands or feet, trouble sleeping, feeling agitated or anxious, headaches and shaking. However, these symptoms are generally mild to moderate and disappear after 1-2 weeks of discontinuing Zotral 50 Tablet.
What are the symptoms of overdose of Zotral 50 Tablet?
The symptoms of overdose of Zotral 50 Tablet include nausea, dizziness, fever, vomiting, confusion, shakiness, and a rapid heartbeat. Whereas, serious side effects include fainting, delirium, heart problems, and changes in blood pressure. If you experience such symptoms immediately contact your doctor or seek emergency medical services in a nearby hospital.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Stahl SM, editor. Sertraline. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 625-30.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1253-58.
- Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 22 Mar. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 22 Mar. 2019] (online) Available from:
- Singh HK, Saadabadi A. Sertraline. [Updated 2023 Feb 13]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023. [Accessed 06 Aug. 2023] (online) Available from:
- Kornstein SG, Pearlstein TB, Fayyad R, Farfel GM, Gillespie JA. Low-dose sertraline in the treatment of moderate-to-severe premenstrual syndrome: efficacy of 3 dosing strategies. J Clin Psychiatry. 2006 Oct;67(10):1624-32. [Accessed 06 Aug. 2023] (online) Available from:
- Sertraline [Package Insert]. Gangtok, Sikkim: Torrent Pharmaceuticals Ltd.; 2022. [Accessed 06 Aug. 2023] (online) Available from:
- Sertraline Hydrochloride [Prescribing Information]. Morgantown, WV: Viatris Specialty LLC; 2023. [Accessed 06 Aug. 2023] (online) Available from:
Marketer details
Name: Micro Labs Ltd
Address: 27, RACE COURSE ROAD, BANGALORE-560 001, INDIA
Country of origin: India
Expires on or after: February, 2026
A licensed vendor partner from your nearest location will deliver Zotral 50 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
Expires on or after: February, 2026
A licensed vendor partner from your nearest location will deliver Zotral 50 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
In case of any issues, contact us
Email ID: [email protected]Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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