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Evolocumab

Information about Evolocumab

Evolocumab Uses

Evolocumab is used in the treatment of high cholesterol, multiple sclerosis (MS), atherosclerosis (plaque deposition inside the arteries) and psoriasis.

How Evolocumab works

Evolocumab works by preventing the production of LDL cholesterol to decrease the amount of cholesterol that may build up on the walls of the arteries and block blood flow to the heart, brain, and other parts of the body.

Common side effects of Evolocumab

Nasopharyngitis (inflammation of the throat and nasal passages), Upper respiratory tract infection, Infection, Influenza, Back pain, Injection site reactions (pain, swelling, redness)

CONTENT DETAILS

Written By

Dr. Surabhi Srivastava

BDS

Reviewed By

Dr. Rajeev Sharma

MBA, MBBS

Written By

Dr. Lipika Khurana

PGDHHM, BDS

Reviewed By

Dr. Rajeev Sharma

MBA, MBBS

Written By

Dr. Surabhi Srivastava

BDS

Reviewed By

Dr. Rajeev Sharma

MBA, MBBS

Written By

Dr. Surabhi Srivastava

BDS

Reviewed By

Dr. Rajeev Sharma

MBA, MBBS

Written By

Dr. Lipika Khurana

PGDHHM, BDS

Reviewed By

Dr. Rajeev Sharma

MBA, MBBS

Written By

Dr. Surabhi Srivastava

BDS

Reviewed By

Dr. Rajeev Sharma

MBA, MBBS

Written By

Dr. Sakshi Jain

MS, BDS

Reviewed By

Dr. Rajeev Sharma

MBA, MBBS

Written By

Dr. Surabhi Srivastava

BDS

Reviewed By

Dr. Rajeev Sharma

MBA, MBBS

Written By

Dr. Anuj Saini

MMST, MBBS

Reviewed By

Dr. Rajeev Sharma

MBA, MBBS

Written By

Dr. Swati Mishra

BDS

Reviewed By

Dr. Rajeev Sharma

MBA, MBBS

Last updated

20 Feb 2025 | 05:01 AM (UTC)

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Available Medicine for Evolocumab

RepathaDr Reddy's Laboratories Ltd

₹218071 variant(s)

Expert advice for Evolocumab

Before taking Evolocumab, inform your doctor if you are allergic to rubber or latex since the needle covers on the syringe contain dry natural rubber.
Inform your doctor immediately if you experience swelling, fatigue, muscle weakness, or muscle pain.
Your doctor may check your liver function before starting the treatment and regularly thereafter.
If you are diabetic, monitor your blood sugar level regularly as Evolocumab may increase your blood sugar levels.
Lifestyle changes like a low-fat and salt diet, exercise, not smoking, and cutting down on the amount of alcohol you normally drink may help Evolocumab work better.

Frequently asked questions for Evolocumab

Evolocumab

Q. How long does it take for Evolocumab to work?

Evolocumab can help lower bad cholesterol (LDL) in just 1 month, with a 63% reduction in just 3 months. However, results may vary from one person to another. Consult your doctor if you do not see any improvement in your cholesterol levels.

Q. How is Evolocumab different from statin?

Statins stop your liver from making as much cholesterol. Evolocumab helps your liver clear bad cholesterol by limiting the actions of a protein called PCSK9, which means less bad cholesterol in your blood.

Q. Does Evolocumab reduce heart attacks?

Evolocumab is an injectable prescription medicine used in adults to lower cholesterol levels and thus reduce the risk of a heart attack.

Q. How is Evolocumab administered?

Evolocumab is given under the skin (subcutaneously), in the abdomen, thigh, or upper arm every 2 weeks or once monthly.

Q. For how long should I take Evolocumab?

Evolocumab should be taken for as long as it is prescribed. If you suddenly stop taking Evolocumab, your cholesterol levels will rise once again.

Q. What is LDL or bad cholesterol?

LDL or low-density lipoprotein is called bad cholesterol because it causes a buildup of cholesterol in the blood. This leads to blockage in the heart and is a direct cause of heart attacks, strokes, and peripheral artery disease.

Q. What is HDL or good cholesterol?

HDL or high-density lipoprotein is also called good cholesterol because it carries cholesterol from your blood to your liver to be removed. This reduces the risk of heart disease.

Q. How can I check my cholesterol level?

You can book a lipid profile test with any accredited laboratory. This test helps you monitor your total cholesterol, LDL levels, HDL levels, triglycerides, and the ratio between cholesterol and HDL. You may need to fast for 10-12 hours before giving your blood sample to the laboratory for testing. After receiving your test report, consult a doctor to help you evaluate your test results.

Q. What is the normal cholesterol level in a blood test?

Your total cholesterol level should be 125 to 200 mg/dL, LDL should be less than 100 mg/dL, and HDL should be 40 mg/dL or higher.

Q. What will happen if I have high cholesterol?

If you have a high cholesterol level, it builds up on the walls of your arteries. This condition causes arteries to become narrow, and the narrowed blood vessels reduce blood flow to the heart. This can lead to a heart attack or stroke.

Q. What lifestyle changes can help improve the effectiveness of this medicine?

Along with taking Evolocumab, taking a low-fat diet, exercising regularly, reducing body weight, and limiting alcohol consumption can help improve the effectiveness of this medicine and lower cholesterol levels.