Isoniazid + Vitamin B6 (Pyridoxine) + Rifampicin
Information about Isoniazid + Vitamin B6 (Pyridoxine) + Rifampicin
Isoniazid + Vitamin B6 (Pyridoxine) + Rifampicin Uses
Isoniazid+Vitamin B6 (Pyridoxine)+Rifampicin is used in the treatment of tuberculosis.
How Isoniazid + Vitamin B6 (Pyridoxine) + Rifampicin works
Isoniazid + Vitamin B6 (Pyridoxine) + Rifampicin is a combination of three medicines: Isoniazid, vitamin B6 (pyridoxine) and rifampicin. Isoniazid prevents the TB bacteria from forming their own protective covering, while rifampicin works by inactivating a bacterial enzyme (RNA-polymerase) which is required by these bacteria to make essential proteins and to reproduce. Together, they kill the bacteria and eradicate the infection. Vitamin B6 (pyridoxine) is added to prevent nerve damage which may be a side effect of isoniazid.
Common side effects of Isoniazid + Vitamin B6 (Pyridoxine) + Rifampicin
Nausea, Vomiting, Rash, Fever, Dark colored urine, Sweating, Increased sputum production, Salivation, Watery eyes, Peripheral neuropathy (tingling and numbness of feet and hand), Increased liver enzymes, Jaundice
Expert advice for Isoniazid + Vitamin B6 (Pyridoxine) + Rifampicin
- Isoniazid + Vitamin B6 (Pyridoxine) + Rifampicin should be taken on an empty stomach but at the same time every day.
- Do not skip any doses and finish the full course of treatment even if you feel better.
- It may cause dizziness. Don't drive or do anything that requires mental focus until you know how the medicine affects you.
- Avoid taking hormone-based birth control methods as Isoniazid + Vitamin B6 (Pyridoxine) + Rifampicin may decrease their effectiveness.
- Avoid consuming alcohol while taking this medication as it can enhance the dizziness.
- Your doctor may monitor your liver function, vision and thyroid function while on treatment with this medicine.