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Lorlatinib

Written By Dr. MayankReviewed By Dr. Rajeev Sharma
Last updated 15 Aug 2025 | 09:09 AM (UTC)

Lorlatinib Uses

Lorlatinib is used in the treatment of non-small cell lung cancer.

How Lorlatinib works

Lorlatinib is an anti-cancer medication. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps to stop or slow the spread of cancer cells.

Common side effects of Lorlatinib

Weight gain, Fatigue, Edema (swelling), High blood pressure, Increased triglyceride level in blood, Peripheral neuropathy (tingling and numbness of feet and hand), Breathlessness, Mood changes, Diarrhea, Cough, Joint pain, Hypercholesterolemia (high cholesterol)
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Expert advice for Lorlatinib

  • Take Lorlatinib at the same time every day to maintain steady levels in your body.
  • Swallow the medicine whole with water and do not crush, chew, or split it.
  • Avoid grapefruit or grapefruit juice, as it can increase side effects.
  • Let your doctor know if you notice mood changes, confusion, or memory problems.
  • Keep a regular check on your cholesterol and liver levels as advised during Lorlatinib treatment.