Pegylated Liposomal Irinotecan
Information about Pegylated Liposomal Irinotecan
Pegylated Liposomal Irinotecan Uses
Pegylated Liposomal Irinotecan is used in the treatment of pancreatic cancer.
How Pegylated Liposomal Irinotecan works
Pegylated Liposomal Irinotecan is a special form of a cancer-fighting drug called Irinotecan. Irinotecan works by blocking the ability of cancer cells to divide and grow, which eventually leads to their death. It does this by targeting an enzyme called topoisomerase I, which cancer cells need to replicate their DNA. In this formulation, Irinotecan is enclosed in tiny fat-like particles called liposomes and is pegylated, meaning it’s coated with a substance (PEG) that makes it stay in the bloodstream longer. This helps the drug stay active in the body for a longer period, giving it more time to reach the cancer cells. The liposomes also help target the drug more specifically to cancer cells, reducing the side effects on healthy cells.
Common side effects of Pegylated Liposomal Irinotecan
Diarrhea, Fatigue, Vomiting, Nausea, Decreased appetite, Stomatitis (Inflammation of the mouth), Fever, Lymphopenia, Decreased white blood cell count (neutrophils)
Available Medicine for Pegylated Liposomal Irinotecan
OnivydeServier India Private Limited
₹990001 variant(s)
Expert advice for Pegylated Liposomal Irinotecan
- Treatment with Pegylated Liposomal Irinotecan can lead to dehydration, especially if you experience diarrhea or vomiting. Drink plenty of water and electrolytes throughout the day to keep your body hydrated.
- Pegylated Liposomal Irinotecan is most effective when given on schedule. Make sure to attend all infusion appointments as directed by your doctor and inform them of any concerns or side effects between sessions.
- Pegylated Liposomal Irinotecan can affect your white blood cells, making you more prone to infections. Regular blood tests will be necessary to monitor your counts. Report any signs of infection (fever, chills) immediately.
- Fatigue is a common side effect, but light exercise like walking can help improve energy levels and mood. Rest when needed, but aim to stay active as much as you can.
- Avoid large crowds and people who are sick to reduce the risk of infection. Wash your hands frequently and practice good hygiene to keep your immune system protected.