Information about Rifampicin

Rifampicin Uses

Rifampicin is used in the treatment of tuberculosis and leprosy.

How Rifampicin works

Rifampicin is an antibiotic. It works by inactivating a bacterial enzyme (RNA-polymerase) which is required by bacteria to make essential proteins and to reproduce.

Common side effects of Rifampicin

Low blood platelets, Dizziness, Vomiting, Nausea, Fever, Abdominal pain, Skin rash, Hepatitis (viral infection of liver), Headache, Chills, Paradoxical reactions, Increased aspartate aminotransferase, Increased alanine aminotransferase, Increased bilirubin in the blood
CONTENT DETAILS
Written By
BDS
Reviewed By
MD (Pharmacology), MBBS
Last updated
13 Jun 2023 | 11:25 AM (UTC)

We provide you with authentic, trustworthy and revelant information

Want to know more

Available Medicine for Rifampicin

R-CinLupin Ltd
25 to ₹1055 variant(s)
RifampilaAlbert David Ltd
5 to ₹603 variant(s)
KemorifaChemo Biological
431 variant(s)
CarPan Pharmaceuticals Ltd
251 variant(s)
RifaliteElite Pharma Pvt Ltd
531 variant(s)
RifacureVostok & Wilcure Remedies
531 variant(s)
MonocinOverseas Healthcare Pvt Ltd
14 to ₹515 variant(s)
TibrifAgron Remedies Pvt Ltd
201 variant(s)
RifasolAsoj Soft Caps Pvt Ltd
23 to ₹823 variant(s)
CoxbactAlpic Remedies Ltd
441 variant(s)

Expert advice for Rifampicin

  • Your doctor has prescribed Rifampicin to cure your infection and improve symptoms.
  • It is best taken on an empty stomach. If you get an upset stomach, try taking it with small portions of food. 
  • Your urine, tears and other secretions may become orange-red in colour. Avoid using contact lenses since they may become discolored.
  • Tell your doctor about all other medicines you are taking as Rifampicin can interact with many medicines.
  • Avoid taking hormone-based birth control methods as Rifampicin may decrease their effectiveness.
  • Tell your doctor immediately if you experience unusual tiredness or loss of appetite, fever or chills.

Frequently asked questions for Rifampicin

Rifampicin

Q. Is rifampin a penicillin/amoxicillin/sulfa drug?

No. Rifampin is an antibiotic commonly used in the treatment of tuberculosis and leprosy. It has a structure and mechanism of action different from penicillin or amoxicillin (amoxicillin belongs to the class of penicillin antibiotics). The chemical structure and mechanism of action of rifampin is different from sulfa drugs

Q. Is rifampin bacteriostatic or bactericidal?

Rifampin is a bactericidal drug. It acts by blocking the activity of a bacterial enzyme called DNA-dependent RNA polymerase which essential for important life processes in the bacteria, thereby killing the bacteria

Q. Is rifampin an inducer or inhibitor?

Rifampin is an inducer (increases activity) of an important liver enzyme system that is responsible for the final processing and elimination of several drugs from the body

Q. What is R-cin 600 used for?

R-cin 600 is a trade name for active drug rifampin 600 mg. Rifampin is an antibiotic commonly used in the treatment of tuberculosis and leprosy. It is also used in the prevention of meningococcal meningitis and Haemophilus influenza infections. It may also be used in combination with other drugs to treat infections-Brucellosis, Legionnaires disease or serious staphylococcal infections

Q. What is R-cinex/Macox plus/R-cinex 600?

R-cinex and Macox plus are trade names for a combination of active drugs rifampin and isoniazid. It is used in the treatment of tuberculosis. R-cinex 600 and Macox plus contains 600 mg of active drug rifampin and 300 mg of active drug isoniazid

Q. Can I take rifampin with ibuprofen/acetaminophen (Tylenol)?

Rifampin has no known serious drug interaction with ibuprofen or acetaminophen (trade name: Tylenol). Inform your doctor about all the medication you are currently taking to avoid interactions that may reduce effectiveness of any treatment or aggravate side effects

Q. Does rifampin cause weight gain/weight loss/ hair loss/ constipation/ yeast infection?

No. Changes in body weight, hair loss or triggering constipation are not among the known side effects of rifampin. Rifampin is an antibiotic commonly used in the treatment of tuberculosis and leprosy. It has no known effect on causing yeast infections

Q. Does rifampin cause headaches?

Yes. Headache is a possible side effect of rifampin

Q. Does rifampin change urine color/turn urine orange?

Yes. Taking rifampin may change the color of your urine (skin, sweat, saliva, tears and feces) to brownish-red or orange. This effect is not harmful

Q. Does rifampin cause liver damage?

Rifampin is safe when used at prescribed doses for the prescribed duration. Constant monitoring of liver function is important while on treatment with rifampin. Taking drugs like saquinavir, ritonavir with rifampin can cause severe liver damage. Do consult your doctor if you have any liver problem before taking rifampin.

INDIA’S LARGEST HEALTHCARE PLATFORM

260m+
Visitors
31m+
Orders Delivered
1800+
Cities
Get the link to download App
Reliable

All products displayed on Tata 1mg are procured from verified and licensed pharmacies. All labs listed on the platform are accredited

Secure

Tata 1mg uses Secure Sockets Layer (SSL) 128-bit encryption and is Payment Card Industry Data Security Standard (PCI DSS) compliant

Affordable

Find affordable medicine substitutes, save up to 50% on health products, up to 80% off on lab tests and free doctor consultations.

LegitScript approved
India's only LegitScript and ISO/ IEC 27001:2022 certified online healthcare platform

Know more about Tata 1mgdownArrow

Access medical and health information

Tata 1mg provides you with medical information which is curated, written and verified by experts, accurate and trustworthy. Our experts create high-quality content about medicines, diseases, lab investigations, Over-The-Counter (OTC) health products, Ayurvedic herbs/ingredients, and alternative remedies.

Order medicines online

Get free medicine home delivery in over 1800 cities across India. You can also order Ayurvedic, Homeopathic and other Over-The-Counter (OTC) health products. Your safety is our top priority. All products displayed on Tata 1mg are procured from verified and licensed pharmacies.

Book lab tests

Book any lab tests and preventive health packages from certified labs and get tested from the comfort of your home. Enjoy free home sample collection, view reports online and consult a doctor online for free.

Consult a doctor online

Got a health query? Consult doctors online from the comfort of your home for free. Chat privately with our registered medical specialists to connect directly with verified doctors. Your privacy is guaranteed.