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Sugammadex

Written By Dr. Lipika KhuranaReviewed By Dr. Rajeev Sharma
Last updated 18 May 2023 | 04:27 PM (UTC)

Sugammadex Uses

Sugammadex is used in the treatment of Reversing the effects of certain drugs used during surgery.

How Sugammadex works

Sugammadex binds to the specific muscle relaxants (vecuronium and rocuronium) forming a ‘complex’ that inactivates these muscle relaxants and prevents them showing an effect. Consequently, the muscles contract and begin to work normally again.

Common side effects of Sugammadex

Vomiting, Pain, Nausea, Hypotension (low blood pressure), Headache
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Expert advice for Sugammadex

  • If you have been taking contraceptive pills, consider additional, non-hormonal methods of contraception (condoms) for the next 7 days following Sugammadex administration to avoid getting pregnant.
  • Inform your doctor if you have liver or kidney disorders prior to administration of this medicine.

Frequently asked questions for Sugammadex

Sugammadex is indicated for the reversal of neuromuscular blockade induced by rocuronium bromide and vecuronium bromide in patients aged 2 years and older undergoing surgery.
Although rare, Sugammadex can cause serious allergic reactions in some people. Symptoms can show up within 5 minutes of getting Sugammadex, and can include redness and swelling of the eyes, and throat, skin redness, difficulty breathing. Other, less serious symptoms of an allergic reaction, can include nausea, itching, and rash.
Sugammadex may reduce the contraceptive effect of birth control pills. It is advisable to use effective oral contraceptive pills during and for 7 days after the administration of Sugammadex to avoid getting pregnant.
No, Sugammadex is not recommended for use in patients with severe renal impairment, including those requiring dialysis.