Total IgE
Understanding Total IgE
What is Total IgE?
The Total IgE, also known as the Immunoglobulin E test, helps identify allergic reactions and immune responses by measuring the levels of Immunoglobulin E (IgE) antibodies in the blood. This test aids in detecting various allergies, including seasonal allergies, food allergies, insect sting allergies, parasitic infections, and some immune disorders.
Immunoglobulin E (IgE) is a type of antibody produced by the immune system that helps to defend the body against potential threats or allergies. The body makes many different types of IgE, each of which is specific to a substance that triggers an immune response, such as pollen, dust mites, food allergens, and insect venom. When the immune system encounters an allergen, it triggers the production of IgE antibodies, which bind to other immune cells.
The Total IgE test measures the amount of IgE antibodies in the blood. However, it does not help to identify the specific type of IgE antibody. An IgE test may be needed if you have asthma or allergy symptoms, like itchy or watery eyes, swelling, shortness of breath, skin rash, congestion, or sneezing. For people with allergy-induced asthma, testing may help to determine the right treatment and suitable dosage. The Total IgE test may also be needed if you have symptoms of an immune disorder or a parasitic infection, such as abdominal pain, cough, diarrhea, dry skin, hives, etc.
No fasting is required for this test. You can eat and drink normally as per your routine. Also, let your doctor know about any medications you might be taking, as some of these medications (such as antihistamines) could affect your test results if taken before this test.
Test result ranges are approximate and may differ slightly between labs depending on the methodology and laboratory guidelines. Talk to your doctor about your specific test results. The results will help the doctor determine your medical condition, make recommendations for lifestyle modifications such as diet and exercise, decide whether or not medication will be required to manage your condition, and formulate your overall treatment plan.
What is Total IgE used for?
The Total IgE test can be done:
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If you experience allergy symptoms such as itchy or watery eyes, swelling, shortness of breath, skin rash, congestion, or sneezing.
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To track and monitor treatment progress and effectiveness
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If a parasitic infection or allergic respiratory disease is suspected.
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In individuals with a family history of allergies.
What does Total IgE measure?
Immunoglobulins are antibodies (proteins) produced by plasma cells (specific immune cells) when the body recognizes bacteria, viruses, other microorganisms, or any other unknown substances as harmful foreign antigens (allergy-causing substances or allergens) to the immune system. There are five types of immunoglobulins: IgA, IgG, IgM, IgD, and IgE.
Unlike other antibodies, IgE is primarily associated with immune responses to allergenic substances, such as plant pollen, latex, pet dander, mold, eggs, peanuts, bee venom, and strawberries. Typically, IgE is present in tiny amounts in the blood. When the immune system encounters an allergen, it triggers the production of IgE antibodies. The Total IgE test measures the concentration of these IgE antibodies in the blood, providing insights into the presence and severity of allergies.
Interpreting Total IgE results
Interpretations
IgE < 64.0o kUA/L
*Reference range may vary from lab to lab