Active Vitamin B12 (Holotranscobalamine)

Active Vitamin B12 (Holotranscobalamine) test helps to diagnose and monitor the amount of Holotranscobalamin (holoTC), a biologically active form of vitamin B12, that is essential for transporting and utilising vitamin B12 in the body. Also, it helps monitor the effectiveness of the treatment for vitamin B12 deficiency and identify the cause of anemia and nerve damage (neuropathy). You may get this test done if you have symptoms such as burning and numbness of hands and legs, extreme tiredness, pale skin etc. Testing for holoTC may be more sensitive in detecting vitamin B12 deficiency, as it reflects the biologically active form of the vitamin that is available in the body. HoloTC testing may be used to evaluate neurological and cardiovascular disorders, as low levels of holoTC have been associated with these conditions. Testing may be used to guide treatment decisions and monitor response to treatment. Other potential uses for holoTC testing include evaluating gastrointestinal disorders or the response to vitamin B12 supplementation in certain populations. Accurate and appropriate testing for holoTC is crucial for optimal patient care, as abnormal levels of these forms of vitamin B12 can have significant health consequences. Measures such as eating fish, dairy products, fortified breakfast cereals, soy milk, etc., can help to prevent the vitamin B12 deficiency.