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Anti Cardiolipin IgG Antibody

Also known as Cardiolipin Antibody IgG, Anticardiolipin antibody, ACLA test

₹899

You need to provide

Blood

This test is for

Male, Female

Test Preparation

No special preparation is required.

Understanding Anti Cardiolipin IgG Antibody

What is Anti Cardiolipin IgG Antibody?

The Anti Cardiolipin IgG Antibody is a blood test that detects the presence of immunoglobulin G (IgG) antibodies targeting cardiolipins, a type of phospholipid in cell membranes. These antibodies are often associated with autoimmune disorders, particularly Antiphospholipid Syndrome (APS), which increases the risk of blood clots, recurrent miscarriages, and other complications.

Antiphospholipid syndrome (APS) is an autoimmune disorder characterized by antiphospholipid antibodies in the blood. These antibodies target phospholipid molecules, such as cardiolipin, leading to an increased risk of pregnancy complications and thrombotic events, such as deep vein thrombosis (DVT), pulmonary embolism (PE), stroke, and myocardial infarction. The Anti Cardiolipin IgG Antibody helps detect the presence of anticardiolipin immunoglobulin G (IgG) which helps diagnose and manage APS.

Since anticardiolipin IgG antibodies are produced later in an immune response and can persist in the bloodstream for a longer duration. Their presence in the blood may indicate a chronic or long-standing immune response. Thus, the Anti Cardiolipin IgG Antibody test is valuable in diagnosing chronic conditions or ongoing immune dysregulation, such as persistent clotting disorders like APS or other autoimmune diseases like lupus.

Doctors may recommend the anticardiolipin antibody IgG test for individuals with a history of unexplained blood clots, recurrent miscarriages, or those with symptoms suggestive of antiphospholipid syndrome. Additionally, the test may be recommended for individuals with systemic autoimmune disorders, such as systemic lupus erythematosus (SLE), as APS frequently coexists with these conditions. The Anti Cardiolipin IgG Antibody test is also beneficial in monitoring the effectiveness of treatment and managing autoimmune diseases, such as APS, SLE, and other autoimmune conditions where anticardiolipin antibodies can be present.

Cardiolipin antibody levels can fluctuate, and a single test may not provide a definitive diagnosis. Hence, the Anti Cardiolipin IgG Antibody test is usually repeated several weeks later to determine whether the antibody is temporary or persistent, allowing the doctors to facilitate a tailored care approach for individuals with blood clotting disorders and autoimmune conditions.

No special preparation is needed before the Anti Cardiolipin IgG Antibody test. However, you should inform your doctor about any medications or supplements you take, as certain medications may affect the test results.

Lab test results may vary across laboratories. Do not try to self-medicate at home based solely on these results, and always consult a doctor for a proper understanding of the test results.The insights from this test helps the doctor tailor appropriate treatment plans to mitigate the risk of clotting and its associated complications.

What is Anti Cardiolipin IgG Antibody used for?

The Anti Cardiolipin IgG Antibody test is done:

To diagnose autoimmune disorders like antiphospholipid syndrome (APS) and systemic lupus erythematosus (SLE).
When you have symptoms consistent with an autoimmune disorder.
To identify the cause of unexplained blood clots (thrombotic episodes), recurrent miscarriages in women, especially in the second and third trimesters of pregnancy, premature labor, or pre-eclampsia.
To monitor treatment response for autoimmune disorders.

What does Anti Cardiolipin IgG Antibody measure?

The Anti Cardiolipin IgG Antibody test detects specific immunoglobulins IgG antibodies, against cardiolipin, a phospholipid found in cell membranes. These antibodies can indicate autoimmune disorders such as antiphospholipid syndrome (APS) and systemic lupus erythematosus (SLE).

IgG antibodies are typically produced by the immune system later in an immune response and remain in the body for a longer time period, suggesting a more chronic or ongoing immune system activation. Therefore, the anticardiolipin IgG test is often used to diagnose chronic conditions or long-term immune responses, such as persistent blood clot formation in disorders like antiphospholipid syndrome (APS).

Interpreting Anti Cardiolipin IgG Antibody results

Interpretations

RESULT IN GPL	REMARKS
< 15	Negative
15 - 20	Equivocal
20 - 80	Low positive
> 80	High positive

Answers to Patient Concerns & Frequently Asked Questions (FAQs) about Anti Cardiolipin IgG Antibody

Frequently Asked Questions about Anti Cardiolipin IgG Antibody

Q. What is the Anti Cardiolipin IgG Antibody test?

The Anti Cardiolipin IgG Antibody test is a blood test that measures the levels of immunoglobulin G (IgG) antibodies directed against cardiolipin, a phospholipid found in cell membranes. The presence of these antibodies may indicate an increased risk of thrombotic events and certain autoimmune disorders, particularly antiphospholipid syndrome (APS).

Q. Why is the Anti Cardiolipin IgG Antibody performed?

This test is performed to assess the risk of thrombotic events, such as deep vein thrombosis (DVT), pulmonary embolism (PE), stroke, and myocardial infarction, in individuals suspected of having APS or other autoimmune disorders associated with antiphospholipid antibodies. It is also used in the evaluation of recurrent miscarriages and pregnancy complications.

Q. Who should consider getting the Anticardiolipin IgG test?

Individuals with a history of unexplained thrombotic events, recurrent miscarriages, or autoimmune disorders such as systemic lupus erythematosus (SLE) may be recommended to undergo the test. Additionally, those experiencing symptoms suggestive of APS or atypical symptoms of thrombosis may benefit from testing.

Q. How is the Anti Cardiolipin IgG Antibody test performed?

A phlebotomist (a trained professional to perform blood draws) will clean your skin using an antiseptic alcohol cotton swab or wipe and take blood samples from your vein using a needle. The blood sample will be stored safely and transported to the laboratory for analysis.

Q. Do I need to fast before taking the Anti Cardiolipin IgG Antibody test?

No fasting is required for this test. You can schedule it at your convenience without avoiding food or water beforehand.

Q. What do the results of the Anticardiolipin IgG Test indicate?

The presence of anticardiolipin IgG antibodies may suggest an increased risk of thrombotic events and autoimmune disorders, particularly APS. However, the interpretation of results requires consideration of clinical factors and additional laboratory tests, as false-positive results can occur.

Q. What are the symptoms of antiphospholipid syndrome (APS)?

Common symptoms of APS are blood clots in the legs, discoloration, tenderness, swelling of the legs, repeated miscarriages or stillbirths, chest pain, low platelets, discomfort in the arms, back, or neck, irregular heartbeat, etc.

Q. Is there a cure for antiphospholipid syndrome?

There is no such cure for antiphospholipid syndrome yet. However, timely and proper treatment can significantly reduce the risk of excessive and irregular blood clotting. Furthermore, an anticoagulant medicine per the doctor’s prescription can help you manage the symptoms.

Q. What other tests might I have along with the Anti Cardiolipin IgG Antibody test?

The additional tests may vary at your doctor’s discretion. However, commonly prescribed tests include a complete blood cell count, partial thromboplastin time and activated prothromboplastin time, antinuclear antibody test, and antiphospholipid antibody test.

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