Anti-CCP Antibody

Rheumatoid arthritis (RA) is an autoimmune (a condition in which the body's natural defense system mistakenly attacks normal/healthy cells) and an inflammatory condition that causes inflammation (painful swelling) of the joints. In addition to the joints, RA sometimes also affects other body parts, including skin, eyes, lungs, or heart.

The Anti-CCP Antibody test checks for the presence and level of Anti-CCP antibodies in your blood. These antibodies are produced by your immune system in response to certain proteins found in the joints in individuals with RA. These antibodies are specific to RA and their presence can be detected even before the symptoms start.

Studies suggets that more than 75% of people with RA test positive for Anti-CCP antibodies. This test helps doctors identify RA early and distinguish it from similar conditions like psoriatic arthritis or juvenile idiopathic arthritis. This test is more specific than other tests like the Rheumatoid Factor (RF) test.

Doctors may suggest this test if you have joint pain, swelling, warmth, morning stiffness, or lumps under the skin. A positive result means these antibodies are in your blood, which makes RA more likely. A negative result does not rule out RA but may mean there’s a lower chance.

No special preparation is needed. You can eat and drink normally. Results may vary based on your age, gender, health, and other factors. Share your full medical history with your doctor to help them better understand your condition and make a suitable treatment plan, including diet, exercise, or medicines.