Sperm Antibody Total

Anti-sperm antibodies (ASA) are abnormal immune proteins that attack sperm cells as if they were harmful invaders. Normally, the immune system defends the body against infections, but in some cases, it wrongly identifies sperm as foreign and produces antibodies against them.

In men, these antibodies may develop after testicular injury, surgery (such as vasectomy reversal), or reproductive tract infections. They can attach to the sperm head, tail, or midpiece, making it harder for sperm to swim, pass through cervical mucus, or fertilize the egg. In women, the immune system may form antibodies in the blood or cervical mucus, impairing sperm function and preventing conception.

The Anti Sperm Antibody test is important in evaluating unexplained infertility, repeated pregnancy failures, or reduced sperm motility despite normal sperm count. It may also be recommended in men after testicular trauma, surgery, or chronic reproductive tract infections, and in women when immune-related infertility is suspected. By detecting anti-sperm antibodies, the test contributes to the overall fertility work-up as part of a comprehensive evaluation and not as a standalone test for treatment decisions. 

No special preparation is required for the Sperm Antibody Total test. Inform the doctor about all the medications and supplements currently being taken, as these may affect the test results.

Test result ranges are approximate and may differ slightly between labs depending on the methodology and laboratory guidelines. Do not self-medicate and always consult a doctor to understand the test results correctly. 

Please note: This is an outsourced test. The sample is collected by TATA 1MG and processed at a NABL accredited partnered lab.