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Anti Thyroid Antibodies Panel

Anti Thyroid Antibodies Panel Includes 2 testsView All
22792700 15% Off
You need to provide
Blood
This test is for
Male, Female
Test Preparation
  1. No special preparation is required.

Understanding Anti Thyroid Antibodies Panel


What is Anti Thyroid Antibodies Panel?

An Anti Thyroid Antibodies Panel is a blood test that assesses the presence of specific antibodies associated with autoimmune thyroid disorders. These antibodies are directed against thyroid peroxidase and thyroglobulin and are called as anti-thyroid peroxidase (TPO) and anti-thyroglobulin (TG) respectively. These antibodies help us to diagnose and manage autoimmune disorders of thyroid such as Hashimoto’s thyroiditis and Grave’s disease. 

The thyroid gland, a small, butterfly-shaped organ in the neck, secretes specific proteins called thyroid peroxidase (TPO) and thyroglobulin (TG) that are crucial for thyroid hormone production (T3, T4 and TSH). These hormones regulate metabolism, body temperature, and growth.

In an Anti Thyroid Antibodies Panel, two primary antibodies examined are anti-TPO and anti-TG, playing a pivotal role in the immune system’s response to the thyroid. Their high levels may suggest autoimmune thyroid conditions. Hashimoto’s thyroiditis, featuring long-term thyroid inflammation, often shows high anti-TPO and anti-TG antibodies. On the other hand, Grave’s disease, an autoimmune disorder causing hyperthyroidism, may exhibit increased anti-TPO antibodies. 

The Anti-TG antibodies test is often performed alongside other tests such as TSH, T3, T4 to provide a more comprehensive view of thyroid function and to diagnose autoimmune thyroid disorders. 

An Anti Thyroid Antibodies Panel helps diagnose and manage autoimmune thyroid disorders, guide treatment decisions, and assess thyroid health. This test is useful in understanding the role of the immune system in thyroid dysfunction and facilitating a tailored care approach for individuals with thyroid-related autoimmune conditions. 

If thyroid hormone tests indicate dysfunction, an Anti Thyroid Antibodies Panel may be ordered to explore autoimmune causes. During pregnancy, an Anti Thyroid Antibodies Panel plays an important role in assessing thyroid health and identifying potential risks to the expecting mother and the growing baby. Also, for women with persistent elevated thyroid antibodies postpartum, there may be an increased risk of developing permanent hypothyroidism. 

Usually, no special preparation is required before undertaking an Anti Thyroid Antibodies Panel test. However, if done alongside thyroid function tests (TSH, T3, T4), inform your doctor about medications or supplements you are taking. While maintaining the continuity of your thyroid medications, avoid biotin (Vitamin B7), an over-the -counter supplement two days before an Anti Thyroid Antibodies Panel, as it can impact the test results.

Lab test results may vary across different laboratories. Discuss your test results with the doctor. Sometimes combining test results, health history, and symptoms helps in thyroid disorder diagnosis through an Anti Thyroid Antibodies Panel. 

What is Anti Thyroid Antibodies Panel used for?

An Anti Thyroid Antibodies Panel is done:

  • To detect specific antibodies associated with autoimmune thyroid disorders.

  • To assess thyroid health and function, especially in cases where abnormal thyroid levels are detected.  

  • To assess the risk of developing thyroid-related disorders such as hypothyroidism or hyperthyroidism.

  • To differentiate autoimmune disorders of the thyroid, such as Hashimoto’s thyroiditis or Grave’s disease, from other causes of thyroid dysfunction, like non-autoimmune goiter.

  • To evaluate thyroid involvement in non-thyroid related autoimmune disorders such as rheumatoid arthritis (RA), systemic lupus erythematosus (SLE). 

  • To monitor the autoimmune response over time, especially in individuals with known thyroid conditions or a history of autoimmune thyroid diseases.

  • To assess the risk of developing autoimmune thyroid disorders , especially in individuals with a family history of autoimmune thyroid diseases. 

  • To monitor the effectiveness of treatment for autoimmune thyroid disorders. 

  • During pregnancy to identify potential risks and complications related to thyroid disorders that may affect both the mother and the baby.

  • As a part of assessment of infertility. 

What does Anti Thyroid Antibodies Panel measure?

Contains 2 tests

An Anti Thyroid Antibodies Panel measures the presence and levels of antibodies that target the thyroid gland. This includes antibodies such as anti-thyroid peroxidase (TPO) and anti-thyroglobulin (TG) . Elevated levels of these antibodies indicate an autoimmune response against the thyroid, which can help diagnose autoimmune thyroid disorders like Hashimoto’s thyroiditis and Grave’s disease. 

 

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Anti-TPO Antibody(Anti-Thyroid Peroxidase Antibody)

In autoimmune thyroid disorders, such as Hashimoto's thyroiditis and Graves’ disease, the immune system produces antibodies against thyroid peroxidase (TPO), an enzyme found in the thyroid gland. An Anti-TPO Antibody(Anti-Thyroid Peroxidase Antibody) test detects and measures the levels of these anti-thyroid peroxidase (anti-TPO) antibodies in your blood.

TPO is found in the cells of the thyroid follicle and helps produce the thyroid hormones thyroxine (T4) or triiodothyronine (T3). The presence of anti-TPO antibodies indicates autoimmune activity against the thyroid gland. These antibodies contribute to inflammation and damage to thyroid cells, thus leading to thyroid dysfunction.

Know more about Anti-TPO Antibody(Anti-Thyroid Peroxidase Antibody)

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Anti Thyroglobulin Antibody

An Anti Thyroglobulin Antibody test measures the presence of antibodies directed against the protein thyroglobulin in the blood. These antibodies are called antithyroglobulin (anti-TG) antibodies that target the thyroid gland. Elevated levels of these antibodies indicate an autoimmune response against the thyroid, which can help diagnose autoimmune thyroid disorders like Hashimoto’s thyroiditis and Grave’s disease.

Monitoring the levels of these antibodies helps in the diagnosis, management, and understanding of autoimmune thyroid conditions, helping doctors formulate an appropriate care plan. 

Know more about Anti Thyroglobulin Antibody

Answers to Patient Concerns & Frequently Asked Questions (FAQs) about Anti Thyroid Antibodies Panel


Frequently Asked Questions about Anti Thyroid Antibodies Panel

Q. Why do I need an Anti Thyroid Antibodies Panel?

An Anti Thyroid Antibodies Panel is done to detect autoimmune thyroid disorders like Hashimoto’s thyroiditis or Grave’s disease. Elevated antibodies indicate an immune response against the thyroid, helping diagnose and manage these conditions.

Q. Is an Anti Thyroid Antibodies Panel painful?

No, an Anti Thyroid Antibodies Panel involves a simple blood draw, which may cause mild discomfort. The pain is usually temporary, and the benefits of obtaining valuable health information outweigh any temporary discomfort.

Q. How often should the Anti Thyroid Antibodies Panel be done?

Frequency of testing depends on the individual’s health condition and the doctor’s recommendations. It is typically done at the initial diagnosis and subsequently as advised by the doctor.

Q. Can an Anti Thyroid Antibodies Panel predict future thyroid dysfunction?

Yes, an Anti Thyroid Antibodies Panel can indicate an increased risk of future thyroid dysfunction. Elevated levels of antibodies such as Anti-thyroid Peroxidase (anti-TPO) and Anti-Thyroglobulin (anti-TG) suggest an autoimmune response, providing valuable information that may predict the development of thyroid disorders over time.

Q. Do thyroid antibodies affect pregnancy?

Yes, the presence of thyroid antibodies,especially Anti-thyroid Peroxidase (anti-TPO), can impact pregnancy. Elevated levels of these antibodies may increase the risk of complications such as miscarriage, preterm birth, and developmental problems in the baby. It is important for pregnant women with thyroid antibodies to receive proper medical guidance and monitoring for a healthy pregnancy.

Q. What is an autoimmune disorder?

An autoimmune disorder is a condition where the immune system mistakenly attacks the body’s own cells, tissues or organs, leading to inflammation and damage.

Q. What are the other tests that can be done alongside an Anti Thyroid Antibodies Panel?

An Anti Thyroid Antibodies Panel is often done along with other tests, such as thyroid function test (TSH, T3, T4), thyroid scan, thyroid ultrasound, complete blood count test, C-reactive protein test or Erythrocyte Sedimentation rate test. It is important to note that the specific test recommended will depend on the individual’s symptoms, medical history and the doctor’s assessment.
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Anti Thyroid Antibodies Panel test price for other cities


Price inMumbaiRs. 2070
Price inBangaloreRs. 2279
Price inNew DelhiRs. 2279
Price inHyderabadRs. 2279
Price inPuneRs. 1900
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References

  1. Fröhlich E, Wahl R. Thyroid Autoimmunity: Role of Anti-thyroid Antibodies in Thyroid and Extra-Thyroidal Diseases. Front Immunol. 2017 May 9;8:521. [Accessed 22 Dec. 2023]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5422478/ External Link
  2. Engler H, Riesen WF, Keller B. Anti-thyroid peroxidase (anti-TPO) antibodies in thyroid diseases, non-thyroidal illness and controls. Clinical validity of a new commercial method for detection of anti-TPO (thyroid microsomal) autoantibodies. Clin Chim Acta. 1994 Mar;225(2):123-36. [Accessed 22 Dec. 2023]. Available from: https://pubmed.ncbi.nlm.nih.gov/8088002/ External Link
  3. Tipu HN, Ahmed D, Bashir MM, Asif N. Significance of Testing Anti-Thyroid Autoantibodies in Patients with Deranged Thyroid Profile. J Thyroid Res. 2018 Apr 11;2018:9610497. [Accessed 22 Dec. 2023]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5925209/ External Link
  4. Swain M, Swain T, Mohanty BK. Autoimmune thyroid disorders-An update. Indian J Clin Biochem. 2005 Jan;20(1):9-17. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3454167/ External Link
  5. Franco JS, Amaya-Amaya J, Anaya JM. Thyroid disease and autoimmune diseases. In: Anaya JM, Shoenfeld Y, Rojas-Villarraga A, et al., editors. Autoimmunity: From Bench to Bedside [Internet]. Bogota (Colombia): El Rosario University Press; 2013 Jul 18. Chapter 30. [Accessed 22 Dec. 2023]. Available from: https://www.ncbi.nlm.nih.gov/books/NBK459466/ External Link
  6. Meena M, Chopra S, Jain V, Aggarwal N. The Effect of Anti-Thyroid Peroxidase Antibodies on Pregnancy Outcomes in Euthyroid Women. J Clin Diagn Res. 2016 Sep;10(9):QC04-QC07. [Accessed 22 Dec. 2023]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5072023/ External Link
  7. Siriwardhane T, Krishna K, Ranganathan V, Jayaraman V, Wang T, Bei K, Ashman S, Rajasekaran K, Rajasekaran JJ, Krishnamurthy H. Significance of Anti-TPO as an Early Predictive Marker in Thyroid Disease. Autoimmune Dis. 2019 Jul 28;2019:1684074. [Accessed 22 Dec. 2023]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6699358/ External Link
  8. Hashimoto’s Disease. [Internet]. NIH; Jun. 2021. [Accessed 22 Dec. 2023]. Available from: https://www.niddk.nih.gov/health-information/endocrine-diseases/hashimotos-disease External Link
  9. Grave’s Disease. [Internet]. NIH; Nov. 2021. [Accessed 22 Dec. 2023]. Available from: https://www.niddk.nih.gov/health-information/endocrine-diseases/graves-disease External Link
  10. Thyroid Antibody [Internet]. Rochester, NY: University of Rochester Medical Center; [Accessed 22 Dec. 2023]. Available from: https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=167&contentid=thyroid_antibody External Link
  11. Thyroid Antithyroglobulin Antibody [Internet] Rochester, NY: University of Rochester Medical Center; [Accessed 22 Dec. 2023]. Available from: https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=167&contentid=thyroid_antithyroglobulin_antibody External Link
  12. Jo K, Lim DJ. Clinical implications of anti-thyroglobulin antibody measurement before surgery in thyroid cancer. Korean J Intern Med. 2018 Nov;33(6):1050-1057. [Accessed 22 Dec. 2023]. Available from: https://pubmed.ncbi.nlm.nih.gov/30396251/ External Link
  13. Jiang N, Jiao B, Zhang L, Li J, Li Y, Lin C. Application of thyroglobulin and anti-thyroglobulin antibody combined with emission computed tomography in the adjuvant diagnosis of differentiated thyroid carcinoma. Ann Med. 2023 Dec;55(1):2232372. [Accessed 22 Dec. 2023]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10339774/ External Link
  14. Latif Z, Crupie MJ. Aberrant Thyroid Function Tests in a Patient Taking Biotin Supplements. Cureus. 2019 Aug 1;11(8):e5297. [Accessed 22 Dec. 2023]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6768618/ External Link
  15. Odhaib SA, Mansour AA, Haddad NS. How Biotin Induces Misleading Results in Thyroid Bioassays: Case Series. Cureus. 2019 May 23;11(5):e4727. [Accessed 22 Dec. 2023]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6663274/ External Link
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