Test Detail
Understanding the Test
Test Measures
References
Other Tests
Content created by
Written by
Dr. Shreya Gupta
BDS, MDS - Oral and Maxillofacial Pathology
Reviewed by
Dr. Ashish Ranjan
MBBS, MD (Pharmacology)
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Bilirubin

You need to provide
Urine
This test is for
Male, Female
Test Preparation
  1. The urine sample must preferably be the first-morning midstream urine (part of urine that comes after the first and before the last stream). Collect the urine sample in a sealed and sterile screw-capped container provided by our sample collection professional. Ensure that the urethral area (from where the urine is passed) is clean & the container doesn't come in contact with your skin. Women are advised not to give the sample during the menstrual period unless prescribed.

Understanding Bilirubin


What is Bilirubin?

The Bilirubin is a non-invasive test that detects bilirubin in the urine sample. It helps assess liver health and diagnose various conditions such as liver dysfunction, bile duct obstruction etc.

Bilirubin is a yellow pigment produced during the normal breakdown of red blood cells.Normally, bilirubin is processed by the liver and excreted in bile. However, when the liver is damaged or bile ducts are blocked, bilirubin spills over into the blood and is excreted in the urine. The urine bilirubin test detects bilirubin, and tells how well your liver is working to process and eliminate bilirubin. 

The Bilirubin test helps detect liver diseases such as hepatitis, cirrhosis, and bile duct obstruction. It is also useful in diagnosing conditions associated with increased red blood cell destruction, such as hemolytic anemia. Additionally, this test can monitor the progression of known liver conditions and the effectiveness of treatments.

Doctors may recommend the Bilirubin test when there are signs or symptoms of liver disease, such as jaundice, dark urine etc., or  when the results of liver function tests show deranged results. 

Elevated bilirubin levels in the urine can indicate liver diseases or hemolytic disorders. Conversely, low or absent bilirubin levels may suggest biliary obstruction or severe liver dysfunction where bilirubin is not adequately processed.

Drink enough water to provide a urine sample. A mid-stream urine sample should be collected into a sterile container provided by the sample collection professional. Women are advised not to give the sample during their menstrual period unless prescribed, as it can interfere with certain test results. Inform your doctor about all the medications or supplements that you may be taking as these may affect the test results , potentially requiring adjustments or temporary discontinuation before the test. 

Don't self-medicate at home solely based on these results and always consult a doctor for proper understanding of the test results. Narrate your complete medical history to help the doctor correlate your clinical and laboratory findings. The results will help them determine your medical condition and formulate your treatment plan.

What is Bilirubin used for?

The Bilirubin test is done: 

  • To diagnose and monitor liver diseases such as hepatitis or cirrhosis.
  • To diagnose bile duct problems, like bile duct inflammation or blockage. 
  • To monitor jaundice, a condition that causes yellowing of eyes or skin.
  • To detect genetic disorders like Crigler–Najjar syndrome, Gilbert’s syndrome etc.
  • To help support the diagnosis of hemolytic anemia (as a result of increased breakdown of red blood cells). 
  • To monitor the effectiveness of ongoing treatment for liver or bile duct disorders.

What does Bilirubin measure?

The Bilirubin test measures the levels of bilirubin present in the urine. Bilirubin is a by-product of the breakdown of old red blood cells, processed by the liver. This test is crucial in assessing liver function and detecting liver diseases.

Normally, the liver converts bilirubin into a form that can be excreted into bile and eventually eliminated from the body. When liver function is impaired, the amount of bilirubin in the urine can change, serving as an important indicator of abnormalities such as liver disease or bile duct blockage.

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