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Understanding the Test
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Interpreting Results
FAQ's
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References
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C - Peptide, Postprandial

Also known as C-Peptide Test, Postprandial C-Peptide Test , Insulin C-Peptide Test , Proinsulin C-Peptide Test, Connecting Peptide Insulin Test
8791050 16% Off
You need to provide
Blood
This test is for
Male, Female
Test Preparation
  1. Sample to be given exactly 2 hours after starting meal or as advised by the physician.

Understanding C - Peptide, Postprandial


What is C - Peptide, Postprandial?

The C - Peptide, Postprandial is a blood test that measures the concentration of C-peptide (a byproduct released by the pancreas) after consuming a meal. This test helps assess how well your body produces insulin, crucial for diagnosing diabetes and monitoring insulin-related conditions.

The C - Peptide, Postprandial test is tailored for individuals with diabetes. It helps doctors understand how well the pancreas is making insulin, which is vital for managing the condition effectively. During this test, the level of C-peptide, a protein fragment released when insulin is produced, is measured in the blood 2 hours after the meal (postprandial). C-peptide levels provide valuable information about the body’s own insulin secretion , distinguishing between endogenous insulin (produced by the pancreas) and exogenous insulin (administered externally). This distinction is important in understanding various conditions, particularly diabetes, as this test helps determine whether insulin resistance or impaired insulin secretion is the underlying cause. 

Doctors may recommend the C-Peptide, Post Prandial test if an individual experiences symptoms such as sudden spikes in blood sugar, difficulty in managing glucose levels despite treatment, or when a more detailed understanding of insulin secretion patterns is required. It is particularly beneficial for individuals with diabetes as it helps differentiate between the causes of high blood sugar levels—whether due to insufficient insulin production or insulin resistance. It can be especially useful for diagnosing type 2 diabetes and distinguishing it from type 1 diabetes, as well as for evaluating the effectiveness of diabetes management strategies. Additionally, it aids in understanding how well insulinomas (pancreatic tumors) are managed by treatment and whether their response is favorable. Furthermore, this test can also be used to assess the function of pancreatic islet cells following a transplant and to evaluate treatment responses for insulinomas.

The C - Peptide, Postprandial test is typically done two hours after the meal. It is important to eat a standard meal that is not high in sugar or carbohydrates before the test. It is also important to inform the doctor about any medications or supplements you take, as some of them may affect blood glucose levels and need to be adjusted before the test.

Lab test results may vary across different laboratories. Abnormal test results require an expert interpretation; therefore, never try to self-medicate at home based solely on these results, and always consult a doctor for a proper understanding of the test results. The results will help them evaluate your medical condition and formulate an overall treatment plan. 

What is C - Peptide, Postprandial used for?

The C - Peptide, Postprandial test is done: 

  • To evaluate the ability of the pancreas to produce insulin in response to food intake.
  • To differentiate between type 1 and type 2 diabetes by assessing insulin production levels after meals.
  • To monitor the effectiveness of diabetes treatments, especially in relation to post-meal glucose control.
  • To monitor the effectiveness of insulinomas ((pancreatic tumors) treatment and to detect its recurrence.
  • To provide insights into insulin secretion and beta-cell function in various metabolic conditions.
  • To assess pancreatic function following islet cell transplants and ensure the success of the procedure.

What does C - Peptide, Postprandial measure?

The C - Peptide, Postprandial test measures the concentration of C-peptide in the blood after eating. C-peptide is a byproduct of insulin production, released in equal amounts with insulin by the pancreas. By assessing C-peptide levels post-meal, healthcare providers can evaluate how effectively the pancreas is responding to glucose intake and whether insulin production is adequate. This test is crucial for diagnosing and managing diabetes effectively, helping to distinguish between type 1 and type 2 diabetes, and tailoring personalized treatment plans to optimize glucose control.

Interpreting C - Peptide, Postprandial results


Interpretations

The normal range of C Peptide level in blood lies between 1.1 ng/ml and 3.4 ng/ml. A higher value indicates more insulin production, and a lower value indicates less insulin production.


Answers to Patient Concerns & Frequently Asked Questions (FAQs) about C - Peptide, Postprandial


Frequently Asked Questions about C - Peptide, Postprandial

Q. What is a C-Peptide, Postprandial test?

The C-Peptide, Postprandial test measures the level of C-peptide in your blood after 2 hours post meals. C-peptide is a substance produced by the pancreas that helps to determine how much insulin is being produced in the body.

Q. Why might I need this test?

The test is used to evaluate insulin production and to help distinguish between different causes of abnormal blood sugar levels. It can be useful in diagnosing and managing diabetes, monitoring insulin resistance, assessing insulin production in type 1 versus type 2 diabetes, and monitoring the treatment of insulinomas or evaluating pancreatic function after a transplant.

Q. How should I prepare for the C - Peptide, Postprandial test?

For accurate results, you should eat a regular meal and then have your blood drawn exactly two hours later. It is important to follow any specific instructions provided by your doctor regarding meal composition and preparation to ensure the reliability of the test results.

Q. Why is the test conducted two hours after a meal?

The test is performed two hours after a meal to evaluate how your body responds to food. This timing allows for an accurate assessment of how much insulin your pancreas is producing in response to a meal, which is crucial for diagnosing and managing conditions like diabetes and assessing insulin production levels.

Q. What are the risks associated with the C - Peptide, Postprandial test?

The risks associated with this test are generally minimal. However, some people may experience mild pain or discomfort at the site from where the blood sample is taken, which is usually self-limiting.

Q. How often should I book the C - Peptide, Postprandial test?

The frequency of getting the C - Peptide, Postprandial test depends on the individual circumstances and their diabetes status. However, it is best to follow your doctor's recommendations.

Q. What other tests might I have along with the C-peptide test?

Additional tests may vary at the doctor's discretion. However, commonly prescribed tests include C-peptide fasting test, blood glucose test, glucagon test, insulin test, and HbA1c test.

Q. How does Tata 1mg ensure accurate lab test results?

Tata 1mg ensures accurate lab test results through certified laboratories that use advanced technology and adhere to stringent quality control measures. This commitment to high standards guarantees reliable results.
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C - Peptide, Postprandial test price for other cities


Price inBangaloreRs. 879
Price inMumbaiRs. 879
Price inPuneRs. 879
Price inHyderabadRs. 879
Price inNew DelhiRs. 879
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References

  1. C-peptide (Blood) [Internet]. USA: NIDDK; Apr.2023 [Accessed 28 Aug. 2024]. Available from: https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=167&contentid=c_peptide_bloodExternal Link
  2. Leighton E, Sainsbury CA, Jones GC. A Practical Review of C-Peptide Testing in Diabetes. Diabetes Ther. 2017 Jun;8(3):475-487. [Accessed 28 Aug. 2024]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5446389/ External Link
  3. Venugopal SK, Mowery ML, Jialal I. Biochemistry, C Peptide. [Updated 2023 Aug 1]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK526026/ External Link
  4. C-peptide test [Internet]. Diabetes.co.uk; 29 Oct. 2023 [Accessed 28 Aug. 2024]. Available from: https://www.diabetes.co.uk/c-peptide-test.html External Link
  5. Maddaloni E, Bolli GB, Frier BM, Little RR, Leslie RD, Pozzilli P, Buzzetti R. C-peptide determination in the diagnosis of type of diabetes and its management: A clinical perspective. Diabetes Obes Metab. 2022 Oct;24(10):1912-1926. [Accessed 28 Aug. 2024]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9543865/ External Link
  6. Vollenbrock CE, Mul D, Dekker P, Birnie E, de Vries-Velraeds MMC, Boesten L, Groen J, Geelhoed-Duijvestijn PHLM, Aanstoot HJ, Wolffenbuttel BHR. Fasting and meal-stimulated serum C-peptide in long-standing type 1 diabetes mellitus. Diabet Med. 2023 Feb;40(2):e15012. [Accessed 28 Aug. 2024]. Available from: https://pubmed.ncbi.nlm.nih.gov/36398450/ External Link
  7. Sokooti S, Kieneker LM, Borst MH, Muller Kobold A, Kootstra-Ros JE, Gloerich J, van Gool AJ, Heerspink HJL, T Gansevoort R, Dullaart RPF, Bakker SJL. Plasma C-Peptide and Risk of Developing Type 2 Diabetes in the General Population. J Clin Med. 2020 Sep 17;9(9):3001. [Accessed 28 Aug. 2024]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7564789/ External Link

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