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Understanding the Test
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Content created by
Written by
Dr. Shreya Gupta
BDS, MDS - Oral and Maxillofacial Pathology
Reviewed by
Dr. Ashish Ranjan
MBBS, MD (Pharmacology)
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Celery

You need to provide
Blood
This test is for
Male, Female
Test Preparation
  1. No special preparation is required.

Understanding Celery


What is Celery?

The Celery test is a blood test tailored to detect specific immunoglobulin E (IgE) antibodies in response to celery proteins (antigens). This test helps identify celery and celery-based food allergies.

Celery is known for its refreshing taste, often used in salads, soups, and juices, and is rich in vitamins, minerals, and fiber. However, some individuals can have allergic reactions to celery, causing stomach problems, skin rashes, or more serious reactions. The Celery test helps detect a celery allergy by checking for specific antibodies (IgE) that the body makes against proteins present in celery. This test helps confirm if the immune system is mistakenly treating celery as a threat and causing an allergy.

The Celery test is recommended when individuals experience symptoms like swelling, itching, or discomfort in the mouth or throat, skin rashes, nausea, stomach pain, or diarrhea after eating celery or celery-based foods. It helps separate celery allergies from other conditions like food intolerances or oral allergy syndrome (OAS), a type of food allergy that causes allergic reactions in the lips, mouth, and throat upon eating certain raw fruits and vegetables. 

A positive test result for celery-specific IgE antibodies means the individual has an allergy to celery, and it’s usually best to avoid them to prevent reactions. If the result is negative, more tests might be needed to find other causes for the symptoms.

No special preparation is required for the Celery test. However, it is important to inform the doctor about any medications (such as antihistamines) or supplements being taken, as these may affect the test results. Lab test results can vary depending on the specific test method and allergens used, so they should be interpreted alongside clinical symptoms.

What is Celery used for?

The Celery test is done:

  • To confirm a celery allergy in individuals who have reactions after eating them.
  • To identify the cause of symptoms like nausea, stomach pain, itching, or swelling after eating celery.
  • To help formulate treatment plans, including dietary changes and medication to manage allergic reactions.
  • To monitor the effectiveness of ongoing celery allergy treatments.
  • To identify individuals at risk of developing food allergies, especially those with a family history of allergies.

What does Celery measure?

The Celery test measures the amount of specific antibodies (IgE) in the body that react to celery proteins. This test is important for diagnosing celery allergies and distinguishing them from other conditions like food sensitivities or oral allergy syndrome (OAS). It helps doctors understand how severe the allergy might be, guiding the next steps in diagnosis and treatment.

References

  1. Celery allergy confirmed by double-blind, placebo-controlled food challenge: A clinical study in 32 subjects with a history of adverse reactions to celery root [Internet]. ScienceDirect; [Accessed 29 Jan. 2025] Available from: https://www.sciencedirect.com/science/article/abs/pii/S009167490047483X External Link
  2. Dougherty JM, Alsayouri K, Sadowski A. Allergy. [Updated 2023 Jul 31]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK545237/ External Link
  3. Lopez CM, Yarrarapu SNS, Mendez MD. Food Allergies. [Updated 2023 Jul 24]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK482187/ External Link
  4. Causes and prevention of food allergy [Internet]. NIH; 10 Jun. 2024. [Accessed 29 Jan. 2025]. Available from: https://www.niaid.nih.gov/diseases-conditions/food-allergy-causes-prevention External Link
  5. Allergens [Internet]. NIH; 07 Sep. 2022. [Accessed 29 Jan. 2025]. Available from: https://www.niehs.nih.gov/health/topics/agents/allergens/index.cfm External Link
  6. Portnoy JM. Appropriate {test_name} testing and interpretation. Mo Med. 2011 Sep-Oct;108(5):339-43. PMID: 22073491; PMCID: PMC6188374. [Accessed 29 Jan. 2025]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6188374/ External Link
  7. Pollen Food Allergy Syndrome [Internet]. American College of Allergy, Asthma & Immunology. [Accessed 29 Jan. 2025]. Available from: https://acaai.org/allergies/allergic-conditions/food/pollen-food-allergy-syndrome/ External Link

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