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Interpreting Results
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References
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Dehydroepiandrosterone Sulphate

Also known as DHEA-Sulphate
9891100 10% Off
You need to provide
Blood
This test is for
Male, Female
Test Preparation
  1. No special preparation is required.

Understanding Dehydroepiandrosterone Sulphate


What is Dehydroepiandrosterone Sulphate?

A Dehydroepiandrosterone Sulphate test evaluates the level of dehydroepiandrosterone sulphate (DHEAS), a steroid hormone produced by the adrenal glands, two small glands located above your kidneys. This hormone plays a role in producing male and female sex hormones. This test is often done to assess adrenal function and diagnose certain conditions related to hormone imbalance. 

DHEAS serves as a precursor to male and female sex hormones, including testosterone and estrogen. A Dehydroepiandrosterone Sulphate test is important for evaluating adrenal function, as the adrenal gland plays a vital role in hormone production and contributes to various physiological processes. This test is often used with other hormone tests to comprehensively understand an individual’s endocrine system. 

A Dehydroepiandrosterone Sulphate test is typically suggested when a doctor suspects an imbalance in adrenal gland function or when investigating conditions related to excess or deficient adrenal hormone production. 

A Dehydroepiandrosterone Sulphate test is used to determine whether or not your adrenal glands are functioning correctly and to detect adrenal tumors or cancers. It also helps determine the cause of masculine physical characteristics (virilization) in girls and women or early puberty in boys. In females, a Dehydroepiandrosterone Sulphate test is done along with other hormones such as Follicle stimulating hormone (FSH), Luteinizing hormone(LH), prolactin, estrogen, and testosterone, to help diagnose polycystic ovary syndrome (PCOS) and rule out other causes of infertility, lack of menstrual period (amenorrhea), excess hair on the face and body (hirsutism) and other androgen-related disorders. Additionally, a Dehydroepiandrosterone Sulphate test can be conducted in babies with unclear genital development. 

No fasting is required for this test. You can eat and drink normally as per your routine. However, It is important to inform your doctor about any medications, supplements, or medical conditions you may have, as these factors could potentially affect the test results. 

Lab test results may vary across different laboratories. The test results may vary depending on factors like age and underlying illness, among others. Abnormal test results require an expert interpretation; therefore, never try to self-medicate at home based solely on these results, and always consult a doctor for a proper understanding of the test results. The insights from this test help the doctor tailor an appropriate treatment plan.

What is Dehydroepiandrosterone Sulphate used for?

A Dehydroepiandrosterone Sulphate test is done: 

  • To evaluate the function of adrenal glands.

  • To help diagnose congenital adrenal hyperplasia and enlargement of the adrenal glands (hyperplasia) in adults.

  • To investigate adrenal tumors, which can impact hormone production.

  • To identify hormonal imbalances, especially when there is an overproduction or underproduction of DHEAS.

  • In babies with ambiguous genitalia, to understand potential underlying conditions.

  • To assess the onset of puberty in both boys and girls.

  • As a part of investigation for hormonal disorders like Polycystic Ovarian Syndrome (PCOS) in females.

  • To investigate whether hormonal factors contribute to excessive hair growth (hirsutism) or hair loss (alopecia) in females.

  • As a part of fertility assessment to explore potential factors affecting reproductive health.

  • To identify androgen-related problems such as virilization in females. 

  • To help in the differential diagnosis of Cushing syndrome.

  • To monitor the treatment response that may affect adrenal function. 

What does Dehydroepiandrosterone Sulphate measure?

A Dehydroepiandrosterone Sulphate test measures the levels of dehydroepiandrosterone sulphate (DHEAS) in the blood. DHEAS is a steroid hormone that is present in both males and females. It is primarily produced by the adrenal glands, with smaller amounts produced by ovaries in females and testicles in males. 

DHEAS plays a role in developing male secondary sexual characteristics at puberty. The body can convert it into more potent androgens like testosterone and androstenedione. Also, it can be converted into the female hormone estrogen. 

A Dehydroepiandrosterone Sulphate test helps diagnose and differentiate certain endocrine disorders, contributing to a comprehensive understanding of hormonal balance in the body.

Interpreting Dehydroepiandrosterone Sulphate results


Interpretations

Age (Years)

Males (ug/dL)

Females (ug/dL)

11-14

16.60 - 242.70

8.60 - 169.80 

15-19

45.10 - 385.00

61.20 - 493.60

20-24

238.40 - 539.30

134.20 - 407.40

25-34

167.90 - 591.90

95.80 - 511.70

35-44

139.70 - 484.40

74.80 - 410.20

45-54

136.20 - 447.60

56.20 - 282.90

55-64

48.60 - 361.80

29.70 - 182.20

65-70

228.50 - 283.60

33.60 - 78.90

 

Age

Children (ug/dL)

< 1 week

24.60 - 302.80

1 - 4 weeks

8.50 - 317.30

1 - 12 months

31.60 - 214.10

1 - 4 years

32.70 - 276.00

5 - 10 years

24.40 - 209.70

 

Answers to Patient Concerns & Frequently Asked Questions (FAQs) about Dehydroepiandrosterone Sulphate


Frequently Asked Questions about Dehydroepiandrosterone Sulphate

Q. What is a Dehydroepiandrosterone Sulphate test used for?

A Dehydroepiandrosterone Sulphate test is used to evaluate adrenal gland function, diagnose conditions that can affect the adrenal glands, and investigate symptoms of hormone imbalances in both males and females.

Q. How is a Dehydroepiandrosterone Sulphate test performed?

A healthcare provider will draw a blood sample from a vein in your arm. The blood sample is then sent to a laboratory, where it is analyzed for DHEAS levels.

Q. Do I need to fast before taking a Dehydroepiandrosterone Sulphate test?

No fasting is required for this test. You can schedule it at your convenience without avoiding food or water beforehand.

Q. What can abnormal results of a Dehydroepiandrosterone Sulphate test indicate?

High levels of DHEAS may indicate an adrenal tumor, PCOS, or other conditions that cause hormone imbalances. Low levels of DHEAS may suggest adrenal insufficiency or hypopituitarism. Consult your doctor for clear understanding and guidance.

Q. How do age and gender affect DHEAS levels?

Usually, DHEAS levels peak in early adulthood and decline with age. Males typically have higher levels of DHEAS than females.

Q. What are the symptoms of high DHEAS in women?

Symptoms of high DHEA levels in women are amenorrhea (absence of menstrual periods), virilization, acne, fertility problems, lack of breasts, male pattern baldness, etc.

Q. Can abnormal DHEAS levels affect fertility?

Yes, high levels of DHEA-S are associated with PCOS which can affect fertility in females.

Q. What conditions can cause low DHEAS?

Low levels of DHEA may be due to adrenal insufficiency like Addison's disease, or hypopituitarism (a condition that may cause low levels of the pituitary hormones that regulate the production of adrenal hormones).

Q. What conditions can cause high DHEAS?

An inherited disorder like congenital adrenal hyperplasia, tumors of adrenal glands, PCOS, etc. can cause high DHEAS.

Q. Can DHEAS supplements be used to normalize DHEAS levels?

While some supplements claim to boost DHEAS levels, it's important to approach them with caution. The body regulates hormone levels, and altering them without medical advice may lead to unintended consequences. Before considering supplements, consult your doctor to ensure they are suitable and safe for your individual health condition.
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Dehydroepiandrosterone Sulphate test price for other cities


Price inBangaloreRs. 989
Price inMumbaiRs. 989
Price inNew DelhiRs. 989
Price inHyderabadRs. 989
Price inKolkataRs. 989
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References

  1. Dehydroepiandrosterone and Dehydroepiandrosterone Sulfate [Internet]. Rochester, NY: University of Rochester Medical Center; [Accessed 13 Feb. 2024]. Available from: https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=167&contentid=dhea External Link
  2. Neunzig J, Bernhardt R. Dehydroepiandrosterone sulfate (DHEAS) stimulates the first step in the biosynthesis of steroid hormones. PLoS One. 2014 Feb 21;9(2):e89727. [Accessed 13 Feb. 2024]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3931814/ External Link
  3. Li K, Liang S, Shi Y, Zhou Y, Xie L, Feng J, Chen Z, Li Q, Gan Z. The Relationships of Dehydroepiandrosterone Sulfate, Erectile Function and General Psychological Health. Sex Med. 2021 Aug;9(4):100386. [Accessed 13 Feb. 2024]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8360929/ External Link
  4. Tang J, Chen LR, Chen KH. The Utilization of Dehydroepiandrosterone as a Sexual Hormone Precursor in Premenopausal and Postmenopausal Women: An Overview. Pharmaceuticals (Basel). 2021 Dec 29;15(1):46. [Accessed 13 Feb. 2024]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8781653/ External Link
  5. Goldman N, Glei DA. Sex differences in the relationship between DHEAS and health. Exp Gerontol. 2007 Oct;42(10):979-87. [Accessed 13 Feb. 2024]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2968710/ External Link
  6. Iliev DI, Braun R, Sánchez-Guijo A, Hartmann M, Wudy SA, Heckmann D, Bruchelt G, Rösner A, Grosser G, Geyer J, Binder G. Very High Dehydroepiandrosterone Sulfate (DHEAS) in Serum of an Overweight Female Adolescent Without a Tumor. Front Endocrinol (Lausanne). 2020 May 6;11:240. [Accessed 13 Feb. 2024]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7218118/ External Link
  7. Leowattana W. DHEAS as a new diagnostic tool. Clin Chim Acta. 2004 Mar;341(1-2):1-15. [Accessed 13 Feb. 2024]. Available from: https://pubmed.ncbi.nlm.nih.gov/14967152/ External Link

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