DPYD Mutation Analysis near me in Bangalore
Understanding DPYD Mutation Analysis in Bangalore
What is DPYD Mutation Analysis in Bangalore?
DPYD mutation analysis is a genetic test that helps detect specific genetic changes (mutations) in the DPYD gene. DPYD gene encodes Dihydropyrimidine dehydrogenase (DPD), an enzyme crucial for pyrimidine catabolism. In the liver, DPD plays a vital role in breaking down most of the commonly prescribed anticancer drugs like 5-FU, thereby regulating the availability of active metabolites. Extensive clinical studies conducted worldwide have demonstrated that approximately 40-60% of cancer patients with DPD deficiency experience severe, life-threatening toxicities when treated with 5-FU. These findings highlight the importance of identifying DPD deficiency through targeted gene sequencing, as it can aid in predicting and managing potential toxicities associated with 5-FU treatment in cancer patients.
Note: Genetic counseling can be provided. If interested, please send the request to this email id: [email protected]
Book a DPYD Mutation Analysis test at home near me
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