Follicle Stimulating Hormone
Understanding Follicle Stimulating Hormone
What is Follicle Stimulating Hormone?
The Follicle Stimulating Hormone test measures the level of follicle-stimulating hormone (FSH). FSH is a hormone that plays a significant role in sexual development and reproduction in men and women. This test is performed to detect and monitor hormonal imbalance, fertility issues and early or delayed puberty.
Follicle-stimulating hormone, or FSH, plays an important role in sexual development and reproduction as it affects the function of ovaries in women and testicles in men. Evaluating the level of FSH is a crucial step in determining reproductive health in both men and women. FSH helps control the menstrual cycles and the production of eggs by the ovaries and facilitates the release of healthy eggs, a process called ovulation. In men, FSH helps control the sperm count and health of the sperm produced by the testicles (testes). FSH levels fluctuate constantly in women, with the highest volumes occurring prior to ovulation. While FSH levels in men normally remain stable after puberty.
The Follicle Stimulating Hormone test can be ordered when a woman is experiencing symptoms of irregular or heavy menstrual periods, has polycystic ovarian syndrome (PCOS), she is facing difficulty in getting pregnant, and/or if problems with the pituitary gland or hypothalamus (an important part of the brain) are suspected. In men, this test can be performed when fertility issues and signs of low testosterone levels, such as decreased sex drive and low muscle mass, are observed. In children, especially teenagers, the Follicle Stimulating Hormone test is done if the doctor suspects a delayed or early puberty. This test may also be performed with other hormone tests such as prolactin, luteinizing hormone (LH), estrogen, and testosterone to give a more comprehensive overview of your sexual and reproductive health.
In women, the preferred time to collect the sample is the second or third day of the menstrual cycle. For men, the test can be done at any time. Before getting tested with the Follicle Stimulating Hormone test let your doctor know about all the medicines that you are taking. Your doctor may ask you to temporarily stop taking certain medications, such as birth control pills to get accurate test results.
Test result ranges are approximate and may differ slightly between labs depending on the methodology and laboratory guidelines. Talk to your doctor about your specific test results. The results will help them determine your medical condition and formulate your overall treatment plan.
What is Follicle Stimulating Hormone used for?
The Follicle Stimulating Hormone test is done to:
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Evaluate the function of reproductive organs (ovaries or testicles).
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Assess menstrual irregularities and conditions such as amenorrhea or oligomenorrhea.
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Detects disorders of the pituitary gland or diseases involving the ovaries.
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Evaluate infertility issues in men and women.
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Evaluate low sperm count in men.
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Assess hypogonadism or gonadal failure in men.
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Assess testicular dysfunction in men.
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Evaluate early or delayed sexual maturation (puberty) in children.
What does Follicle Stimulating Hormone measure?
The Follicle Stimulating Hormone test measures the level of FSH in your body. FSH is produced and subsequently released into the blood by the pituitary gland. Its production is controlled by a feedback mechanism involving a hormone situated in the hypothalamus in the brain. The released FSH travels through your blood and then attaches to receptors in the ovaries and testes. It exerts functional effects on the reproductive organs, such as sexual development, puberty, and maturation. FSH levels vary throughout the menstrual cycle in response to estradiol and progesterone. Any disruption or issue in this feedback mechanism can prevent the normal function of the testicles or ovaries. Thus, determining its level provides crucial information regarding your health.
Interpreting Follicle Stimulating Hormone results
Interpretations
Reference range of FSH is age- and gender-specific. As for women, the reference range is menstrual cycle phase-specific.
The reference range for follicle-stimulating hormone (FSH) is as follows (3rd generation immunochemiluminescence assay):
Females reference range:
· Age 0-7 years: <6.7 mIU/mL
· Age 8 years to adult:
· Follicular phase: 3.1-7.9 mIU/mL
· Ovulation peak: 2.3-18.5 mIU/mL
· Luteal phase: 1.4-5.5 mIU/mL
· Postmenopausal: 30.6-106.3 mIU/mL
Males
· Age 0-7 years: <6.7 mIU/mL
· Age 8 years-adult:1.3-19.3 mIU/mL
The reference range may vary from lab to lab*