Ganglioside IgM Antibody, Serum

Ganglioside IgM antibodies are autoantibodies that target gangliosides, which are complex molecules found in the cell membrane of neurons. Ganglioside IgM Antibody, Serum test detects IgM antibodies against 7 gangliosides, namely GM1, GM2, GM3, GD1a, GD1b, GT1b, and GQ1b. The antibodies can help diagnose multifocal neuropathy, Guillain-Barre syndrome, Miller-Fisher syndrome & sensory neuropathy. The test is done for patients who are likely to suffer from autoimmune central nervous system disorders. The Ganglioside IgM Antibody, Serum test is a medical test that is done for diagnosis and to monitor the progression of these neurological disorders and assess the effectiveness of treatment; evaluate the risk of developing an autoimmune neurological disorder in individuals who have a family history of the disease; to assist in the differential diagnosis of neurological disorders that have similar clinical presentations.

The Ganglioside IgM Antibody, Serum test may be ordered when a person has symptoms like progressive muscle weakness and atrophy; sensory disturbances such as numbness, tingling, or pain; difficulty with balance and coordination; impaired reflexes; vision changes, including double vision or difficulty moving the eyes; facial weakness or paralysis; difficulty speaking or swallowing, and respiratory muscle weakness. Other individuals who may be recommended for a Ganglioside IgM Antibody, Serum test include those who have a family history of autoimmune neurological disorders or have been exposed to certain environmental factors that increase the risk of developing these disorders.