Gastrin near me in Chennai

The Gastrin test measures the concentration of gastrin in the bloodstream. Gastrin is a peptide hormone generated by gastric antrum mucosal G cells. It is involved in regulating gastric acid secretion and gastric motility. Gastrin plays a role in the development and maintenance of the digestive system and other processes.

This test is typically conducted to determine abnormal gastrin production and diagnose disorders related to gastric acid hypersecretion such as Zollinger-Ellison (ZE) syndrome (Zollinger-Ellison (ZE) syndrome is a rare condition characterized by abnormally high levels of stomach acid, leading to peptic ulcers and other related complications), hyperplasia of G-cells, and gastrinomas, which are gastrin-producing tumors. It helps identify pernicious anemia, a condition characterized by the destruction of acid-secreting (parietal) cells of the stomach. Gastrin can serve as an adjunct to clinical assessment, imaging studies, and other tests in the evaluation of patients with recurrent peptic ulcers or chronic gastritis.

This test may be recommended when a patient presents with symptoms of gastric acid hypersecretion, such as abdominal pain, diarrhea, heartburn, or nausea, to investigate possible causes of elevated gastrin levels, such as gastrinoma, ZE syndrome, or pernicious anemia, and to monitor the effectiveness and safety of treatments that affect gastrin levels, such as proton pump inhibitors (PPIs), histamine-2 receptor blockers (H2 blockers), or somatostatin analogs.