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Glucose-6-Phosphate Dehydrogenase (G-6-PD),Qualitative

Also known as G6PD Qualitative Reflex, G6PD deficiency test, Glucose-6-phosphate dehydrogenase test

₹889

You need to provide

Blood

This test is for

Male, Female

Test Preparation

Before a G6PD test, avoid certain medications (sulfonamides, antimalarials, aspirin) and fava beans, as they can affect results. If you've had a recent hemolytic episode or blood transfusion, consult your doctor and wait for a few weeks before testing to ensure accuracy. Fasting is not required, but follow your doctor’s instructions.

Understanding Glucose-6-Phosphate Dehydrogenase (G-6-PD),Qualitative

What is Glucose-6-Phosphate Dehydrogenase (G-6-PD),Qualitative?

The Glucose-6-Phosphate Dehydrogenase (G-6-PD),Qualitative is a qualitative blood test for detection of glucose-6-phosphate dehydrogenase (G-6-PD) enzyme deficiency, an inherited condition affecting red blood cells. It helps detect hemolytic anemia, especially after exposure to specific triggers, such as certain medications, foods, and infections.

Glucose-6-phosphate dehydrogenase (G-6-PD) is an enzyme that plays a crucial role in the proper functioning of red blood cells by protecting them from oxidative damage. A deficiency in this enzyme can lead to hemolytic anemia. In this condition, red blood cells break down faster than the body can produce them. This is particularly triggered by factors such as infections, certain medications, or the consumption of fava beans, a condition known as "favism”.

The Glucose-6-Phosphate Dehydrogenase (G-6-PD),Qualitative test identifies if an individual has enough G-6-PD enzyme activity. Knowing their deficiency status allows individuals to manage their condition by avoiding triggers known to precipitate hemolytic episodes.

The Glucose-6-Phosphate Dehydrogenase (G-6-PD),Qualitative test is recommended for individuals showing signs and symptoms of hemolytic anemia, like fatigue, jaundice, dark urine, shortness of breath, and an enlarged spleen. It is especially useful for those at higher risk, such as males, African Americans, or those with a family history of G-6-PD deficiency. Doctors may also suggest this test before giving certain medications that can cause oxidative stress, like some antibiotics, antimalarials, or sulfa drugs. Additionally, the test is used to screen newborns in areas where G-6-PD deficiency is common.

Before a G6PD test, avoid certain medications (sulfonamides, antimalarials, aspirin) and fava beans, as they can affect test results. If you've had a recent hemolytic episode or blood transfusion, consult your doctor and wait for a few weeks before testing to ensure accuracy. Fasting is not required, but follow your doctor’s instructions.

Lab test results may vary across laboratories. Do not self-medicate. Always consult the doctor to understand the test results correctly. The insights from Glucose-6-Phosphate Dehydrogenase (G-6-PD),Qualitative test will help doctors formulate the overall treatment plans.

What is Glucose-6-Phosphate Dehydrogenase (G-6-PD),Qualitative used for?

The Glucose-6-Phosphate Dehydrogenase (G-6-PD),Qualitative test is done:

To diagnose G6PD deficiency, especially in individuals with unexplained hemolytic anemia.
To evaluate if hemolytic anemia is due to G-6-PD deficiency, especially after exposure to certain drugs, infections, or foods (e.g., fava beans).
To help identify the cause of neonatal jaundice.
To monitor individuals from high-risk ethnic backgrounds who may be at risk of hemolytic episodes.
To assess G6PD enzyme activity before administering medications that may trigger hemolysis, especially antimalarials.
To assess the effectiveness of treatments for conditions related to G-6-PD deficiency, such as during or after a hemolytic episode.

What does Glucose-6-Phosphate Dehydrogenase (G-6-PD),Qualitative measure?

The Glucose-6-Phosphate Dehydrogenase (G-6-PD),Qualitative test measures the activity of the G6PD enzyme in red blood cells. This enzyme is essential for preventing RBCs from oxidative stress. It achieves this by helping to regenerate glutathione, a molecule that neutralizes harmful oxidative substances. When there is not enough G6PD, red blood cells become more vulnerable to damage. This damage can be triggered when someone gets an infection, takes certain medicines (like antibiotics or antimalarials), or eats specific foods like fava beans.

This test helps determine if someone has G6PD deficiency, which is important for managing conditions caused by oxidative stress. If the test shows low or no G6PD enzyme activity, it can explain why someone has recurring issues like hemolytic episodes (where red blood cells break down), jaundice (yellowing of the skin and eyes), and other symptoms. It also helps doctors and patients avoid things that could trigger these problems in the future.

Interpreting Glucose-6-Phosphate Dehydrogenase (G-6-PD),Qualitative results

Interpretations

The qualitative test checks for fluorescence under UV light. If no fluorescence is detected, the test is declared positive.

Answers to Patient Concerns & Frequently Asked Questions (FAQs) about Glucose-6-Phosphate Dehydrogenase (G-6-PD),Qualitative

Frequently Asked Questions about Glucose-6-Phosphate Dehydrogenase (G-6-PD),Qualitative

Q. What is the Glucose-6-Phosphate Dehydrogenase (G-6-PD),Qualitative test?

The Glucose-6-Phosphate Dehydrogenase (G-6-PD),Qualitative test measures the activity of the G6PD enzyme in red blood cells. It helps diagnose G6PD deficiency, a genetic disorder that can make red blood cells more vulnerable to oxidative stress, leading to their premature breakdown (hemolysis).

Q. Why do I need the Glucose-6-Phosphate Dehydrogenase (G-6-PD),Qualitative test?

You may need this test if you have symptoms of hemolytic anemia, such as fatigue, jaundice, dark urine, or if you've experienced episodes of anemia after taking certain medications, eating fava beans, or following an infection. It may also be recommended if there is a family history of G6PD deficiency.

Q. How is the G6PD test performed?

The test involves a simple blood draw, typically from a vein in your arm. The sample is then analyzed in a laboratory to measure the activity level of the G6PD enzyme in your red blood cells.

Q. What do the test results mean?

Normal G6PD activity indicates that you do not have G6PD deficiency. Low or absent G6PD activity may suggest G6PD deficiency, which may explain hemolytic anemia or other related symptoms. Your doctor will provide guidance on how to manage the condition.

Q. Can G6PD deficiency affect pregnancy?

G6PD deficiency can impact pregnancy, particularly if the mother experiences hemolysis or if the baby inherits the condition. Pregnant women with G6PD deficiency should consult their doctors for personalized care and monitoring during pregnancy.

Q. Can newborns be tested for G6PD deficiency?

Yes, in some regions, newborn screening includes testing for G6PD deficiency. Early detection can help prevent complications such as neonatal jaundice and hemolytic episodes.

Q. How often should this test be done?

The doctor's suggestion and the patient's medical history determine how frequently this test is performed. If you have been diagnosed with G6PD deficiency, your doctor may recommend regular testing to monitor your condition.

Q. What symptoms are associated with G6PD deficiency?

Symptoms associated with G6PD deficiency include fatigue, pale skin, shortness of breath, rapid heartbeat, jaundice (yellowing of the skin and eyes), dark urine, and an enlarged spleen. In some cases, individuals may remain asymptomatic until exposed to specific triggers.

Q. Can the Glucose-6-Phosphate Dehydrogenase (G-6-PD),Qualitative test be done at home?

Yes, you can take the Glucose-6-Phosphate Dehydrogenase (G-6-PD),Qualitative test from the comfort of your home with Tata 1mg labs.

Q. How does Tata 1mg ensure accurate lab test results?

Tata 1mg ensures accurate lab test results through certified laboratories that use advanced technology and adhere to stringent quality control measures. This commitment to high standards guarantees reliable results.

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