Hb HPLC (Hb Variants Estimation by HPLC) near me in Dehradun
Understanding Hb HPLC (Hb Variants Estimation by HPLC) in Dehradun
What is Hb HPLC (Hb Variants Estimation by HPLC) in Dehradun?
An Hb HPLC (Hb Variants Estimation by HPLC) test is a specialized test used to identify and quantify normal and abnormal forms of hemoglobin in the blood. It is available at an affordable price in Dehradun with Tata 1mg Labs. Hemoglobin (Hb) is an iron-rich protein that carries oxygen to organs and tissues. An Hb HPLC (Hb Variants Estimation by HPLC) test helps identify hemoglobin variants, such as HbA, HbD, and HbF, crucial for diagnosing conditions marked by abnormal hemoglobin production like thalassemia and anemia. It is valuable for individuals undergoing treatments like transfusions in cases of unexplained anemia or familial blood disorder history, enabling doctors to assess treatment effectiveness.
Your doctor may suggest an Hb HPLC test when a blood disorder such as thalassemia or sickle cell disease is suspected. Fasting is not required for an Hb HPLC (Hb Variants Estimation by HPLC) test; you can eat and drink normally per your daily routine. Inform your doctor if you recently underwent a blood transfusion, which may impact the test results.
What does Hb HPLC (Hb Variants Estimation by HPLC) measure?
An Hb HPLC (Hb Variants Estimation by HPLC) test is used to identify and quantify different types of hemoglobin in the blood to diagnose and monitor specific blood disorders. Different types of hemoglobin are Adult type (HbA2), Fetal type (HbF), Hemoglobin S (HbS), Hemoglobin C (HbC), and Hemoglobin E (HbE), etc.
Normal types of hemoglobin include:
- Hemoglobin (Hgb) A: The most common type of hemoglobin in healthy adults
- Hemoglobin (Hgb) F: Fetal hemoglobin, which is found in unborn babies and newborns. HgbF is replaced by HgbA shortly after birth.
A deranged level of HgbA or HgbF might indicate certain types of anemia.
Abnormal types of hemoglobin include:
- Hemoglobin (Hgb) S: This type of hemoglobin is found in sickle cell anemia, an inherited disorder that causes the body to make stiff, sickle-shaped red blood cells. Sickle cells can get stuck in the blood vessels, causing severe pain, long-term infections, and other complications.
- Hemoglobin (Hgb) C: This type of hemoglobin is associated with hemolytic anemia that develops when your red blood cells are destroyed more easily than normal red blood cells or have a shorter life span than normal red blood cells.
- Hemoglobin (Hgb) E: This type of hemoglobin is mainly found in people of Southeast Asian descent and may be associated with mild anemia or no symptoms.
- Hemoglobin (Hgb) D: Hb D disease (HbDD) is characterized by mild hemolytic anemia and mild to moderate splenomegaly. Hb D Punjab occurs with the most significant prevalence in Gujarat and Sikhs of Punjab.