HE4 With ROMA Index near me in Pune
Understanding HE4 With ROMA Index in Pune
What is HE4 With ROMA Index in Pune?
The HE4 With ROMA Index is a diagnostic test to assess the risk of epithelial ovarian cancer in women and is available with Tata 1mg in Pune. This test combines the measurement of HE4 (Human epididymis protein 4), a protein produced by cells in the ovaries and the lining of the respiratory tract; CA-125 (cancer antigen-125), a tumor marker that is often elevated in women with ovarian cancer; and the Risk of Ovarian Malignancy Algorithm (ROMA) index along with other factors like the woman’s age and menopausal status for calculation of a numerical score. This combination of biomarkers provides valuable information for the early detection and management of ovarian cancer.
The HE4 With ROMA Index test is available in Pune at an affordable price with Tata 1mg labs. It is recommended for women who are above 18 years of age, have an adnexal mass for which surgery is planned, and have not yet been referred to a doctor who specializes in diagnosing and treating cancer (oncologist).
No special preparation is required for this test. You can eat and drink as per your routine. However, providing a brief clinical history or doctor's prescription during sample collection is important. Additionally, indicate the date of your last menstrual period (LMP) or menopausal status.
What does HE4 With ROMA Index measure?
Contains 3 testsThe HE4 With ROMA Index test measures key biomarkers to assess the risk of epithelial ovarian cancer. It includes Human Epididymis Protein 4 (HE4), CA 125, and the Risk of Ovarian Malignancy Algorithm (ROMA) index evaluation. In cases of ovarian cancer, the levels of HE4 and CA 125 are often elevated. The ROMA index combines HE4 levels with CA 125 along with other factors like the woman’s age and menopausal status for the calculation of a numerical score. This combination of biomarkers and clinical history enhances the accuracy of the HE4 With ROMA Index test in predicting the presence of epithelial ovarian cancer, particularly in its early stages. This test is instrumental in women with pelvic masses who have not yet undergone surgery.
What sets the HE4 With ROMA Index test apart is its ability to provide a nuanced assessment of epithelial ovarian cancer risk. While CA 125 alone can sometimes yield false positive results due to its elevation in other conditions like endometriosis, HE4 offers added specificity and precision. Moreover, the ROMA index considers factors like age and menopausal status, further refining the risk assessment. This comprehensive approach not only helps in the early detection of epithelial ovarian cancer but also helps differentiate between malignant (cancerous) and benign (non-cancerous) ovarian masses, guiding doctors in making informed decisions regarding further diagnostic workup and determining whether a woman with a pelvic mass is at high or low risk for ovarian cancer before surgery, which can guide treatment decisions and help in planning surgery.
HE4 - Human Epididymis Protein 4
ROMA Value
CA125 (Cancer Antigen 125)
CA125 is a protein found in most ovarian cancer cells and some normal tissues. A CA125 (Cancer Antigen 125) test is commonly advised to detect ovarian cancer by measuring the amount of CA125 protein in the blood. A deranged level of CA125 antigen may indicate the presence of certain cancers, primarily ovarian cancer or other non-cancerous conditions, including endometriosis, pelvic inflammatory disease, ovarian cysts, etc.
Know more about CA125 (Cancer Antigen 125)