HLA B-27, Flowcytometry near me in Chennai
Understanding HLA B-27, Flowcytometry in Chennai
What is HLA B-27, Flowcytometry in Chennai?
An HLA B-27, Flowcytometry is a blood test that helps to identify the presence of Human Leukocyte Antigen B27(HLA B-27), a specific type of protein present on the surface of white blood cells (WBCs) that helps the body's immune system tell the difference between its own cells and foreign/harmful substances and helps diagnose autoimmune disorders. This test is widely available at an affordable price in Chennai.
Your doctor may suggest an HLA B-27 test if you experience signs and symptoms such as stiffness and chronic pain in the back, neck, or chest, inflammation in eyes, urethra, and joints, the appearance of skin lesions, recurring fever, abdominal pain, or digestive problems indicative of an autoimmune disorder. Additionally, this test is also used during an organ transplant to match donated tissue with the recipient to minimize the risk of organ rejection and improve the success of the transplantation.
No special preparation is needed for this test. You may eat and drink as per your daily routine.
What does HLA B-27, Flowcytometry measure?
An HLA B-27, Flowcytometry test evaluates the presence or absence of HLA B27 antigen to rule out the possibility of any autoimmune disorder. Once recognizing any cell as foreign and dangerous, the human leukocyte antigens (HLA) set out to destroy those cells to protect the body from any harm. The majority of the HLAs protect the body from damage, however, HLA-B27 is a specific type of protein that contributes to the dysfunction of the body’s immune system. The presence of HLA-B27 on the white blood cells can cause the immune system to attack those otherwise healthy cells. When this occurs, it can result in an autoimmune disease.
Answers to Patient Concerns & Frequently Asked Questions (FAQs) about HLA B-27, Flowcytometry in Chennai
Frequently Asked Questions about HLA B-27, Flowcytometry in Chennai
Q. When is an HLA B-27, Flowcytometry test performed?
Q. Is there any risk associated with an HLA B-27, Flowcytometry test?
Q. Does Tata 1mg Labs offer an HLA B-27, Flowcytometry test in Chennai near me?
Q. Is home sample collection facility available for an HLA B-27, Flowcytometry test in Chennai with Tata 1mg Labs?
Q. How can I schedule an HLA B-27, Flowcytometry test with Tata 1mg Labs in Chennai?
Q. What is the cost of an HLA B-27, Flowcytometry test at Tata 1mg Labs in Chennai?
Q. How long does Tata 1mg Labs take to give the reports of an HLA B-27, Flowcytometry test in Chennai?
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References
- Parameswaran P, Lucke M. HLA-B27 Syndromes. [Updated 2023 Jul 4]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK551523/
- Zochling J, Bohl-Bühler MH, Baraliakos X, Feldtkeller E, Braun J. Infection and work stress are potential triggers of ankylosing spondylitis. Clin Rheumatol. 2006 Sep;25(5):660-6.[Accessed 06 Nov. 2023]. Available from: https://pubmed.ncbi.nlm.nih.gov/16633712/
- HLA- B27 Antigen [Internet]. Rochester, NY: University of Rochester Medical Center; [Accessed 28 Nov. 2023]. Available from: https://www.urmc.rochester.edu/encyclopedia/content.aspx?ContentTypeID=167&ContentID=hla_b27_antigen
- N P, Shanmugam SG, Devi SS, Chinambedu Dandapani MP, S R, D'Cruze L. Detection of Human Leukocyte Antigen B27 by Flowcytometry in Patients With Suspected Ankylosing Spondylitis in a Tertiary Care Centre. Cureus. 2021 Feb 25;13(2):e13560. [Accessed 28 Nov. 2023]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8004549/#:~:text=HLA%2DB27%20testing%20is%20routinely%20used%20to%20diagnose%20AS%20since,%2Dpositive%20cases%20%5B12%5D.
- McMichael A, Bowness P. HLA-B27: natural function and pathogenic role in spondyloarthritis. Arthritis Res. 2002;4 Suppl 3(Suppl 3):S153-8. [Accessed 28 Nov. 2023]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3240147/
- Ankylosing Spondylitis. [Internet]. NIH; May. 2023. [Accessed 28 Nov. 2023]. Available from: https://www.niams.nih.gov/health-topics/ankylosing-spondylitis#:~:text=Ankylosing%20spondylitis%20is%20a%20type,help%20us%20move%20and%20bend.
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