Kidney Health Screen
Understanding Kidney Health Screen
What is Kidney Health Screen?
The Kidney Health Screen is a comprehensive assessment tailored to evaluate kidney function and detect potential issues early. It includes a range of blood and urine tests that provide a holistic view of kidney health, helping in the early detection and management of kidney-related conditions.
The Kidney Health Screen test helps assess the overall health and functionality of the kidneys. The kidneys play an important role in filtering waste products, balancing electrolytes, and maintaining fluid balance in the body. This screening package includes key tests to provide a thorough evaluation of kidney function. It includes serum calcium test which measures calcium levels in the blood to assess bone health and kidney function, serum creatinine test which evaluates kidney function by determining the amount of creatinine in the blood, uric acid test which checks for uric acid levels to detect gout and other potential kidney function issues, Blood urea nitrogen (BUN) test which measures the level of urea nitrogen in the blood to assess kidney function and protein metabolism and routine urine examination to detect urine abnormalities, providing insights into kidney and urinary tract health.
The Kidney Health Screen test is recommended for individuals with risk factors such as diabetes, hypertension, a family history of kidney disease or those experiencing symptoms like swelling, fatigue, or changes in urine output. It is also suggested for individuals taking certain medications that may affect kidney function, and as part of routine health checkup to ensure early detection and management of potential kidney issues. Early detection of kidney problems allows for timely intervention, potentially preventing the progression of chronic kidney disease and ensuring better management of overall health.
An overnight fasting is preferred before this test but is not mandatory. Inform your doctor about all the medications and supplements that you may be taking, as these may affect your test results and may require temporary discontinuation before the test. A midstream urine sample should be collected into a sterile container provided by the sample collection professional. Women are advised not to give the sample during the menstrual period unless prescribed, as that can interfere with certain test results.
Test result ranges can vary slightly between labs due to differences in testing methods and guidelines. Abnormal test results require expert interpretation; therefore, do not self-medicate at home solely based on these results and consult your doctor for proper understanding of the test results. Based on the results, your doctor will assess your medical condition, suggest lifestyle changes like diet and exercise, and decide if medication is needed to manage your condition.
What is Kidney Health Screen used for?
The Kidney Health Screen test is done:
- As part of routine health evaluations for overall well-being.
- If you have signs and symptoms that indicate kidney dysfunction such as changes in urine output, swelling, fatigue, stomach pain, muscle cramps, loss of appetite etc.
- To screen for kidney diseases if you have risk factors like obesity, diabetes, high blood pressure, or a family history of kidney disease.
- To monitor kidney function in patients undergoing treatments that can affect the health of kidneys.
- To help determine the effectiveness of dialysis or other ongoing treatments for kidney disease.
What does Kidney Health Screen measure?
Contains 23 testsThe Kidney Health Screen test is tailored to assess the overall function and health of your kidneys. This comprehensive test includes serum calcium test, which helps evaluate calcium metabolism and kidney stone risk ; serum creatinine test to assess kidney filtration efficiency and detect potential kidney dysfunction; uric acid test to identify the risk of gout and kidney stones; and blood urea nitrogen (BUN) test is to evaluate kidney function and detect any possible impairment in the kidneys' ability to remove waste from the blood. Additionally, this profile also includes urine routine & microscopy (Urine R/M) test which provides detailed information on the physical and chemical characteristics of urine, helping to identify infections, kidney disease, and other urinary tract issues. Collectively, these tests provide valuable insights into kidney health and can help detect early signs of kidney disease.
Serum Calcium
The Serum Calcium test measures the levels of calcium in the body. Calcium is the most abundant mineral in the body; most of it is present in the bones and teeth, and the remaining portion (around 1%) is found in the blood. It is usually present in two forms in blood in about equal amounts: "bound calcium," which is attached to proteins in the blood, and "free calcium or ionized calcium," which is not attached to any protein.
The Serum Calcium test cannot be used to check for lack of calcium in your diet or osteoporosis (loss of calcium from bones) as the body can have normal calcium levels even in dietary calcium deficiency. Moreover, the body can normalize mild calcium deficiency by releasing the calcium stored in bones.
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Serum Creatinine
The Serum Creatinine test measures the level of creatinine in the blood. Creatinine is a byproduct of muscles’ wear and tear during energy production. The kidneys remove it from the body by filtering it from the blood and releasing it into the urine. Therefore, blood creatinine levels indicate how well the kidneys are functioning in filtering and removing waste products from the blood. Generally, higher creatinine levels in the blood may indicate reduced kidney function, while lower levels may suggest decreased muscle mass.
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Uric Acid
An Uric Acid test determines the level of uric acid in your body. Uric acid is a nitrogenous compound produced by the metabolic breakdown of purine. Purines are present as nitrogenous bases in the DNA and are also found in food like red meat and seafood.
Most uric acid dissolves in the blood and goes into your kidneys. From there, it passes through your body via the urine. Decreased elimination of uric acid is often a result of impaired kidney function due to kidney disease. In many cases, the exact cause of excess uric acid is unknown. Doctors seldom need to test for low levels of uric acid.
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Urine R/M (Urine Routine & Microscopy)
The Urine R/M (Urine Routine & Microscopy) test involves gross, chemical, and microscopic evaluation of the urine sample.
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Gross examination: It involves visually inspecting the urine sample for color and appearance. Typically, the urine color ranges from colorless or pale yellow to deep amber, depending on the urine’s concentration. Things such as medications, supplements, and some foods such as beetroot can affect the color of your urine. However, unusual urine color can also be a sign of disease.
In appearance, the urine sample may be clear or cloudy. A clear appearance is indicative of healthy urine. However, the presence of red blood cells, white blood cells, bacteria, etc., may result in cloudy urine, indicating conditions such as dehydration, UTIs, kidney stones, etc. Some other factors, such as sperm and skin cells, may also result in a cloudy appearance but are harmless.
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Chemical examination: It examines the chemical nature of the urine sample using special test strips called dipsticks. These test strips are dipped into the urine sample and change color when they come in contact with specific substances. The degree of color change estimates the amount of the substance present. Some common things detected include protein, urine pH, ketones, glucose, specific gravity, blood, bilirubin, nitrites, and urobilinogen.
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Microscopic examination: This involves the analysis of the urine sample under the microscope for pus cells, red blood cells, casts, crystals, bacteria, yeast. and other constituents.
Know more about Urine R/M (Urine Routine & Microscopy)
This further contains
- Urobilinogen
- Ketone
- Nitrite
- Colour
- Appearance
- Specific Gravity
- Pus Cell
- Epithelial Cell
- Casts
- Crystals
- Protein Urine
- Ph for Urine
- Urine Glucose
- Yeast
- Red Blood Cells
- Leucocyte Esterase
- Blood
- Bacteria
- Bilirubin
Blood Urea Nitrogen (BUN)
A Blood Urea Nitrogen (BUN) test measures the levels of urea nitrogen in the blood. Blood urea is a waste product that is formed in the liver when you eat food and the protein is metabolized into amino acids. This process leads to the production of ammonia that is further converted into urea. Both ammonia and urea are nitrogenous compounds. Your liver releases urea into the blood which is then carried out to the kidneys. In the kidneys, urea is filtered from the blood and flushed out of the body via urine. This is a continuous process, so a small amount of urea nitrogen always remains in the blood.
In the case of a kidney or liver disease, there is a change in the amount of urea present in the blood. If your liver produces urea in an increased amount or if there is any problem in kidney functioning, there might be difficulty in filtering out the waste products from the blood, which can result in increased urea levels in the blood.
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Interpreting Kidney Health Screen results
Interpretations
- Urea/ BUN - High levels suggest impaired kidney function caused by acute or chronic kidney disease or rarely due to some other conditions like congestive heart failure or dehydration
- Creatinine - High levels suggest impaired kidney function
- Calcium - Low levels may be seen with kidney failure
- Albumin - Low blood level may indicate that the kidneys cannot prevent albumin from leaking out
- Glucose - High blood level indicate diabetes, which is an important cause of kidney disease
- Uric acid: Higher than normal levels of uric acid in the blood is called Hyperuricemia and may be caused due to kidney diseases, gout, chemotherapy or radiotherapy treatment.
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Urine Routine & MIcroscopy: It includes various tests that detect cells, cell fragments and substances such as crystals or casts in the urine associated with the various conditions