Ku

The Ku antibody test is used to detect antibodies against the Ku protein, which is involved in DNA repair and other cellular processes. These antibodies are associated with certain autoimmune diseases, particularly systemic sclerosis, polymyositis and overlap syndrome such as MIxed Connective tissues disease( MCTD). This test is not commonly prescribed as other autoimmune tests but it is useful in diagnosing and differentiating between autoimmune conditions when patients presents with overlapping symptoms like muscle weakness, joint inflammation etc. The presence of Ku antibodies, along with clinical findings and other laboratory tests, helps doctors tailor treatment plans and better understand the patient's autoimmune profile.