MEDICINES
LAB TESTS
CONSULT DOCTORS
CANCER CARE
AYURVEDA
PARTNERSHIPS
CARE PLAN
Login
|
Signup
Order Summary
0 Test
PROCEED TO CART
Need Help?
MEDICINES
LAB TESTS
DOCTORS
CANCER CARE
How can we help?
Home
MPN Panel 3

MPN Panel 3

Also referred as
Diagnostics and Prognostic panel for subtyping of Myeloproliferative Neoplasm
Myeloproliferative Neoplasm Panel
For men & women
Earliest reports in
336 hours
Contains
4 tests
Know more about this test

The MPN Panel 3 is a genetic test that detects vital mutations associated with myeloproliferative neoplasms (MPNs), a type of blood cancer. It helps doctors diagnose and classify MPNs, plan treatment, and monitor disease progression.

 

 

Samples required
Blood
Find out
Why is this test booked?
Preparation for this test
Sample Collection
Who will collect your samples?

Understanding MPN Panel 3

Chronic myeloproliferative neoplasms (MPNs) are blood disorders in which the bone marrow produces too many red blood cells, white blood cells, or platelets. The {tet_name} is a comprehensive blood test used to evaluate genetic changes in blood cells that are characteristic of MPNs.

The MPN Panel Advanced detects key genetic mutations and fusions, including CALR, JAK2 (exons 12–15), MPL, and the BCR-ABL fusion. This helps doctors identify and classify different types of myeloproliferative neoplasms (MPNs), including both BCR-ABL1–positive and BCR-ABL1–negative conditions such as chronic myeloid leukemia (CML), polycythemia vera (PV), essential thrombocythemia (ET), and primary myelofibrosis (PMF).

Doctors may recommend this panel if you experience symptoms such as fatigue, weakness, night sweats, or an enlarged spleen, or if you have abnormal blood counts. It is also advised for individuals with a family history of MPNs or known genetic risk factors. This test helps diagnose specific MPNs, differentiate between subtypes for appropriate treatment, monitor therapy response, and assess complication risks.

For this test, it is important to submit the clinical history, histopathology report, previous test results, and a doctor’s prescription at the time of sample collection. The Tata 1mg consolidated Test Requisition Form (TRF) must also be duly filled and submitted.

Lab test results may vary across different laboratories. Abnormal test results require an expert interpretation. Therefore, never try to self-medicate at home based solely on these results, and always consult a doctor for proper understanding of the test results.

See more

What does MPN Panel 3 measure?

Contains 4 tests

The MPN Panel 3 detects important genetic mutations and gene fusions that help diagnose and classify myeloproliferative neoplasms (MPNs). This includes CALR mutations, JAK2 mutations (exons 12–15), MPL mutations, and the BCR-ABL1 fusion, which is essential for identifying chronic myeloid leukemia (CML). By analyzing these mutations and fusions, the test provides a comprehensive genetic profile, enabling doctors to accurately diagnose, classify, and manage both BCR-ABL1–positive and BCR-ABL1–negative MPNs. 

Abnormal results may indicate the presence of specific MPNs: BCR-ABL1 fusion may suggest CML, JAK2 mutations may indicate polycythemia vera (PV) or essential thrombocythemia (ET), and CALR or MPL mutations may point to primary myelofibrosis (PMF). Further evaluation and consultation with a hematologist are necessary for accurate diagnosis and appropriate treatment.

CALR
JAK2 (12-15)
MPL

The BCR-ABL Qualitative PCR test checks a blood or bone marrow sample for the presence or absence of BCR-ABL mRNA transcripts, which are produced due to a chromosomal change called t(9;22), also known as the Philadelphia chromosome. If the test is positive, it can identify the specific transcript type, such as p210 (e13a2/e14a2) or p190 (e1a2), which helps doctors understand the type of leukemia and plan treatment accordingly.

Know more about BCR-ABL Qualitative PCR

FAQs related to MPN Panel 3

This is a genetic test that detects key mutations and gene fusions associated with myeloproliferative neoplasms (MPNs), helping doctors diagnose, classify, and manage these blood disorders.
The panel is recommended for individuals with persistently abnormal blood counts, symptoms like fatigue, weakness, night sweats, or an enlarged spleen, or those suspected of having MPNs such as CML, PV, ET, or PMF. It may also be advised for patients with a family history of MPNs.
The test detects mutations in CALR, JAK2 (exons 12–15), MPL, and the BCR-ABL1 fusion, which together help identify both BCR-ABL1–positive and BCR-ABL1–negative MPNs.
Yes, MPNs are blood cancers originating in the bone marrow, where excessive production of red cells, white cells, or platelets occurs.
A phlebotomist will clean your skin using an antiseptic alcohol cotton swab or wipe and take blood samples from your vein using a needle. The blood sample will be stored safely and transported to the laboratory for analysis.
No fasting is required for this test. You can schedule it at your convenience without avoiding food or water beforehand.
No, the MPN Panel 3 is generally safe with minimal risks. However, you may feel slight discomfort during blood sample collection but chances of serious complications are extremely rare.
Symptoms may include fatigue, weakness, night sweats, headaches, weight loss, enlarged spleen, or blood clotting problems. Early stages may be asymptomatic and detected during routine blood tests.
There is currently no complete cure for most MPNs. Early diagnosis and treatment can control symptoms, prevent complications, and improve quality of life. Targeted therapies or bone marrow transplantation may be options depending on disease type and stage.
Content created by
Written by:
Dr. Lipika Khurana
BDS, PGDHHM
Reviewed by:
Dr. Swati Gupta (Anand)
MBBS, MD Lab Medicine
Want to know moreRead our editorial policy
Last Updated21st Dec 2025

MPN Panel 3 test price for other cities

Price inBangaloreRs. 14250
Price inWarangalRs. 14250
Price inHyderabadRs. 14250
Price inAllahabadRs. 14250
Price inBhopalRs. 14250

How does home sample collection work?

Easy online booking

Search for tests and packages, book your preferred time slot and enter your address for seamless at-home lab tests.

Live tracking of phlebotomist

Track our trained phlebotomist's real time location for seamless sample collection.

Safe Sample Collection

Our phlebotomists follow strict safety protocols to collect samples safely at home and on time.

Sample received at lab

Samples are transported securely to our accredited labs with world-class machines for testing by qualified experts.

Quick, Doctor-Verified Reports

Get doctor-approved reports via email and WhatsApp, with options for doctor follow-ups and AI insights.

Download the Tata 1mg app. Trusted healthcare, at your fingertips.

Book tests, track reports, and get AI-powered health insights.

or
Test conducted by
Core Diagnostics Private Limited
ISO, CAP, NABL certified
Know More
Contains 4 tests
CALR
JAK2 (12-15)
MPL
BCR-ABL Qualitative PCR