Multiple Myeloma Comprehensive Panel Quantitative, Serum near me in Bangalore
Understanding Multiple Myeloma Comprehensive Panel Quantitative, Serum in Bangalore
What is Multiple Myeloma Comprehensive Panel Quantitative, Serum in Bangalore?
The multiple myeloma comprehensive panel test includes several components: Serum Protein Electrophoresis (SPEP), Serum Immunofixation Electrophoresis (SIFE), Immunoglobulin Profile (IgG, IgA, and IgM), Free Light-chain assay, and Beta-2 Microglobulin. SPEP identifies abnormal protein levels in the blood, while SIFE further characterizes the specific type of abnormal proteins. Immunoglobulin Profile determines the levels of different immunoglobulins. The Free Light-chain assay quantifies light chains produced by myeloma cells. Beta-2 Microglobulin is a marker of disease burden. These tests aid in diagnosing multiple myeloma, assessing disease stage, and monitoring response to treatment, enabling personalized and effective management of patients with multiple myeloma.
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What does Multiple Myeloma Comprehensive Panel Quantitative, Serum measure?
Contains 9 testsImmunofixation Electrophoresis Serum
Immunoglobulin A
Immunoglobulin M
Beta 2 Microglobulin, Serum
Immunoglobulin G
Free Kappa
Free Lambda
Kappa/Lambda Ratio
The Kappa/Lambda Ratio test measures the balance of two types of free light chains: free kappa light chains and free lambda light chains. These light chains are components of antibodies produced by plasma cells as part of the immune response. Normally, a small amount of free light chains are present in the bloodstream, but in some conditions, such as plasma cell disorders like primary amyloidosis, multiple myeloma, Waldenström macroglobulinemia, and monoclonal gammopathies, the production of these light chains can rise significantly.
By considering the balance between kappa and lambda light chains, rather than just their individual levels, the Kappa/Lambda Ratio test provides a more comprehensive assessment of light chain production and its relevance to diagnosing plasma cell proliferation.
Know more about Kappa/Lambda Ratio
Protein Electrophoresis, Serum
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