PLA2 Receptor Antibody Quantitative, Serum near me in Mumbai
Understanding PLA2 Receptor Antibody Quantitative, Serum in Mumbai
What is PLA2 Receptor Antibody Quantitative, Serum in Mumbai?
PLA2 receptor antibody Quantitative, Serum test detects autoantibodies (specific proteins) against phospholipase A2 receptors (PLA2R) which is useful in the diagnosis of primary membranous glomerulonephritis (PMGN), an autoimmune kidney disease wherein antibodies target glomeruli thus leading to progressive reduction in kidney function. PMGN is the most common cause of nephrotic syndrome. Autoantibodies of class IgG against PLA2R are highly specific for the diagnosis of primary MGN and can be detected in the serum of up to 70-80% of patients. It can be done in people who have persistent proteinuria, even after the exclusion of other causes such as kidney stones, urinary tract infections, and other kidney diseases. This test also helps to monitor treatment response and to check for recurrence of the disease.