RB1 GENE Sequencing With Deletion/Duplication Analysis (MLPA) near me in Howrah

Retinoblastoma (RB) is a childhood eye cancer originating from immature retinal cells. It's the most common eye tumor in kids, with about 1 case per 18,000 to 30,000 births worldwide. RB is linked to changes in the RB1 gene, which normally controls cell growth. Detecting RB1 gene mutations and deletions or duplications is crucial for patient care and family planning.

This test utilizes next-generation sequencing to detect mutations in the RB1 gene, and Multiplex Ligation dependent Probe Amplification (MLPA) to identify any clinically relevant deletion duplications or aberrant methylation in the RB1 gene promoter region.