Sex Hormone Binding Globulin near me in Kolkata
Understanding Sex Hormone Binding Globulin in Kolkata
What is Sex Hormone Binding Globulin in Kolkata?
The Sex Hormone Binding Globulin test is a blood test that measures the level of sex hormone binding globulin, a protein produced by the liver that binds to three sex hormones: estrogen, dihydrotestosterone (DHT), and testosterone. Available at an affordable price in Kolkata, this test is vital for understanding reproductive health, supporting fertility evaluation, and addressing hormonal imbalances.
SHBG test is generally recommended after the testosterone test results are not consistent with clinical signs and symptoms. In men, this test can help diagnose conditions such as hypogonadism (low testosterone levels) and other androgen disorders. In women, it can help evaluate conditions such as polycystic ovary syndrome (PCOS), infertility, and other menopausal symptoms. Furthermore, this test aids in monitoring hormone replacement therapy (HRT), helping doctors decide the appropriate dosage of hormones and tailor the overall treatment plan.
No special preparation is required for this test. Inform your doctor about all the medications and supplements that you may be taking, as these could potentially affect the test results.
What does Sex Hormone Binding Globulin measure?
The Sex Hormone Binding Globulin test measures the level of sex hormone binding globulin (SHBG) protein in the blood and is most often used to help evaluate you for testosterone deficiency or excess. SHBG is produced by the liver and it helps in the transport and regulation of sex hormones, primarily testosterone, dihydrotestosterone (DHT) and estrogen.
When the SHBG protein binds to sex hormones, your tissues can't use those hormones. Your tissues can only use sex hormones that are "free," which means they aren't attached to proteins, such as SHBG. Changes in SHBG levels can affect the amount of hormone used by the body’s tissues.
In men, SHBG binds to sex hormones like testosterone and regulates their levels in the blood. When SHBG levels are higher , less free testosterone is available for the body to use. However, when SHBG levels are lower, more free testosterone is available. This balance is important for maintaining overall health and hormonal function in men.
In women, SHBG plays an integral role in regulating the levels of bioavailable male sex hormones (androgens) and estrogens circulating throughout the body. SHBG has a higher affinity for the androgens testosterone and DHT, and so with the low SHBG, women may have signs and symptoms related to androgen excess.
Answers to Patient Concerns & Frequently Asked Questions (FAQs) about Sex Hormone Binding Globulin in Kolkata
Frequently Asked Questions about Sex Hormone Binding Globulin in Kolkata
Q. What is the Sex Hormone Binding Globulin test?
Q. Why do I need the Sex Hormone Binding Globulin test?
Q. How often should I book the Sex Hormone Binding Globulin test ?
Q. How is the Sex Hormone Binding Globulin test performed?
Q. What precautions should I take before and after the Sex Hormone Binding Globulin test?
Q. What additional tests can be advised along with the Sex Hormone Binding Globulin test?
Q. Can I schedule the Sex Hormone Binding Globulin test online in Kolkata near me?
Q. Is home sample collection facility available for the Sex Hormone Binding Globulin test in Kolkata with Tata 1mg Labs?
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Q. What is the price of the Sex Hormone Binding Globulin test at Tata 1mg Labs in Kolkata?
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References
- Sex Hormone Binding Globulin (Blood) [Internet] Rochester, NY: University of Rochester Medical Center; [Accessed 02 Apr. 2024]. Available from: https://www.urmc.rochester.edu/encyclopedia/content.aspx?ContentTypeID=167&ContentID=shbg_blood
- Laurent MR, Hammond GL, Blokland M, Jardí F, Antonio L, Dubois V, Khalil R, Sterk SS, Gielen E, Decallonne B, Carmeliet G, Kaufman JM, Fiers T, Huhtaniemi IT, Vanderschueren D, Claessens F. Sex hormone-binding globulin regulation of androgen bioactivity in vivo: validation of the free hormone hypothesis. Sci Rep. 2016 Oct 17;6:35539. Accessed 02 Apr. 2024]. Available from: Sex hormone-binding globulin regulation of androgen bioactivity in vivo: validation of the free hormone hypothesis - PMC
- Hammond GL. Diverse roles for sex hormone-binding globulin in reproduction. Biol Reprod. 2011 Sep;85(3):431-41. Accessed 02 Apr. 2024]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480437/
- Selby C. Sex hormone binding globulin: origin, function and clinical significance. Ann Clin Biochem. 1990 Nov;27 ( Pt 6):532-41. Accessed 02 Apr. 2024]. Available from: https://pubmed.ncbi.nlm.nih.gov/2080856/
- Qu X, Donnelly R. Sex Hormone-Binding Globulin (SHBG) as an Early Biomarker and Therapeutic Target in Polycystic Ovary Syndrome. Int J Mol Sci. 2020 Nov 1;21(21):8191. Accessed 02 Apr. 2024]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7663738/
- Pugeat M, Crave JC, Tourniaire J, Forest MG. Clinical utility of sex hormone-binding globulin measurement. Horm Res. 1996;45(3-5):148-55. Accessed 02 Apr. 2024]. Available from: https://pubmed.ncbi.nlm.nih.gov/8964574/
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