SGPT & SGOT
Understanding SGPT & SGOT
What is SGPT & SGOT?
The SGPT & SGOT measures the levels of two important liver enzymes: serum glutamic-oxaloacetic transaminase (SGOT) and serum glutamic-pyruvic transaminase (SGPT) in the blood. These tests are commonly done to assess liver function, diagnose liver disorders, and monitor liver health.
SGOT (Aspartate Aminotransferase) and SGPT (Alanine Aminotransferase) are the two enzymes predominantly found in the liver and play key roles in amino acid metabolism. SGOT is involved in the conversion of aspartate and alpha-ketoglutarate to oxaloacetate and glutamate, while SGPT facilitates the conversion of alanine and alpha-ketoglutarate to pyruvate and glutamate. Both enzymes are crucial for various metabolic processes, including the synthesis and breakdown of proteins. These enzymes are released into the bloodstream when liver cells are injured or destroyed.
Doctors may advise the SGOT and SGPT test when an individual exhibits symptoms suggestive of liver dysfunction, including jaundice (yellowing of the skin or eyes), abdominal pain, dark urine, pale stool, fatigue, and unexplained weight loss. These tests are also done as a part of a standard liver function test (LFT), especially in individuals with risk factors such as excessive alcohol consumption, obesity, diabetes, or a history of liver disease. Additionally, these tests can be used to assess the effectiveness of treatments for liver-related conditions.
No special preparation is required before undergoing SGOT and SGPT tests. However, it is advisable to follow your doctor’s instructions and inform them of any medications or supplements you are taking, as these can impact test results.
Lab test results may vary across laboratories. Abnormal test results require expert interpretation; therefore, do not self-medicate at home solely based on these results and consult your doctor for proper understanding of the test results. Based on the results, your doctor will assess your medical condition, suggest lifestyle changes like diet and exercise, and decide if medication is needed to manage your condition.
What is SGPT & SGOT used for?
The SGPT & SGOT test is done:
- As part of a liver function test (LFT).
- To assess liver function and identify potential liver damage or inflammation.
- If you have symptoms indicating potential liver problems such as jaundice, abdominal pain, or changes in the color of urine and stool.
- To help diagnose liver conditions such as hepatitis, cirrhosis, or fatty liver disease.
- To screen for liver diseases, especially if you have risk factors such as excessive alcohol use, obesity, or a family history of liver disorders.
- To monitor liver function in patients undergoing treatments that might affect the liver.
What does SGPT & SGOT measure?
Contains 2 testsThe SGPT & SGOT test measures the levels of two key liver enzymes in the blood: SGOT (Aspartate Aminotransferase) and SGPT (Alanine Aminotransferase). These enzymes are produced in the liver and are essential for metabolic processes involving amino acids. Elevated levels of SGOT and SGPT can indicate liver damage or inflammation, providing valuable information for diagnosing liver conditions and monitoring liver health. By assessing these enzyme levels, doctors can gain insights into liver function and guide appropriate treatment or management strategies.
SGPT
An SGPT test measures the amount of ALT or SGPT enzyme in your blood. ALT is most abundantly found in the liver but is also present in smaller amounts in other organs like the kidneys, heart, and muscles. Its primary function is to convert food into energy. It also speeds up chemical reactions in the body. These chemical reactions include the production of bile and substances that help your blood clot, break down food and toxins, and fight off an infection.
Elevated levels of ALT in the blood may indicate liver damage or injury. When the liver cells are damaged, they release ALT into the bloodstream, causing an increase in ALT levels. Therefore, the SGPT/ALT test is primarily used to assess the liver's health and to detect liver-related problems such as hepatitis, fatty liver disease, cirrhosis, or other liver disorders.
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SGOT
An SGOT test measures the levels of serum glutamic-oxaloacetic transaminase (SGOT), also known as aspartate aminotransferase (AST), an enzyme produced by the liver. SGOT is present in most body cells, most abundantly in the liver and heart. The primary function of this enzyme is to convert food into glycogen (a form of glucose), which is stored in the cells, primarily the liver. The body uses this glycogen to generate energy for various body functions.
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